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Thyrotropin

More information in Books or onNLM PubMed
Definition: A glycoprotein hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Thyrotropin stimulates THYROID GLAND by increasing the iodide transport, synthesis and release of thyroid hormones (THYROXINE and TRIIODOTHYRONINE). Thyrotropin consists of two noncovalently linked subunits, alpha and beta. Within a species, the alpha subunit is common in the pituitary glycoprotein hormones (TSH; LUTEINIZING HORMONE and FSH), but the beta subunit is unique and confers its biological specificity.  for alpha subunit, coord with GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; THYROTROPIN, BETA SUBUNIT is also available   
See Also Receptors, Thyrotropin
Examples Glycoprotein Hormones, alpha Subunit; Thyrotropin Alfa; Thyrotropin, beta Subunit 		Other names Thyroid-Stimulating Hormone; Thyroid Stimulating Hormone; Hormone, Thyroid-Stimulating; Thyrotrophin; Thyreotropin; TSH (Thyroid Stimulating Hormone)Drugs* : THYTROPAR
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TR1402 peptide  0   Thyrotropin/*analogs & derivatives Receptors, Thyrotropin/agonists. Thyroid 2011 Jul;21(7):783-92
TR1401 peptide  0   Thyrotropin/*analogs & derivatives Receptors, Thyrotropin/agonists. Thyroid 2011 Jul;21(7):783-92
Thyrotropin deficiency, isolated  0   *Hypothyroidism Thyrotropin/deficiency.
thyrostimulin  0   *Glycoproteins Follicle Stimulating Hormone Prolactin Thyrotropin. J Clin Invest 2002 Jun;109(11):1445-52
hTSHbeta.CTPalpha protein, recombinant  0   *Chorionic Gonadotropin *Recombinant Fusion Proteins *Thyrotropin. J Biol Chem 2001 Feb 16;276(7):4543-8
exophthalmos producing substance  9013-46-1   *Thyrotropin.
deglycosylated thyrotropin  0   Thyrotropin/*analogs & derivatives. Endocrinology 1987;121(4):1278
thyrotropin-alpha-lactalbumin-daunomycin conjugate  0   Daunorubicin/*analogs & derivatives Thyrotropin/*analogs & derivatives. Horm Metab Res 1981;13(2):110
thyrotropin-daunomycin conjugate  0   Daunorubicin/*analogs & derivatives Thyrotropin/*analogs & derivatives. Horm Metab Res 1981;13(2):110
dansyl thyrotropin  0   Thyrotropin/*analogs & derivatives. J Biol Chem 254(18):9030;1979
chorionic thyrotropin protein, human  39316-88-6   *Placental Hormones *Pregnancy Proteins *Thyrotropin Placental Hormones. Acta Ob Gyn Scand 55(4):345;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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