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Uridine Phosphorylase

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Definition: An enzyme that catalyzes the transfer of ribose from uridine to orthophosphate, forming uracil and ribose 1-phosphate.      Other names Phosphorylase, Uridine; Phosphorylase, 5-Fluoro-2'-deoxyuridine; 5 Fluoro 2' deoxyuridine Phosphorylase; 5-Fluoro-2'-deoxyuridine Phosphorylase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
uridine phosphorylase-2, human  EC 2.4.2.3   *Uridine Phosphorylase. Biochem Biophys Res Commun 2003 Jul 18;307(1);41-6
5-(phenylselenenyl)acyclouridine  0   *Organoselenium Compounds Uracil/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. Cancer Chemother Pharmacol 2000 ;45(5):351-61
5-benzyluracil  0   Uracil/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. Nucleosides Nucleotides 1999 Nov-Dec;18(11-12):2551-64
5-phenylpyrimidine-2-one  0   *Nucleosides Uridine Phosphorylase/antagonists & inhibitors. Nucleosides Nucleotides 1999 Nov-Dec;18(11-12):2551-64
5-pheylcytosine  0   Cytosine/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. Nucleosides Nucleotides 1999 Nov-Dec;18(11-12):2551-64
1-((2-hydroxyethoxy)methyl)-5-(phenylselenenyl)uracil  153081-01-7   *Organoselenium Compounds Uracil/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. J Med Chem 1993 Dec 24;36(26):4250-4
5-benzyloxybenzylbarbituric acid  138660-08-9   Uracil/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. Biochem Pharmacol 1993 Nov 17;46(10):1849-58
5-(3-benzyloxy)benzyl-1-((2-hydroxyethoxy)methyl)barbituric acid  138660-09-0   *Barbiturates Uridine Phosphorylase/antagonists & inhibitors. Biochem Pharmacol 1993 Oct 5;46(7):1273-83
5-(benzyloxybenzyloxybenzyl)acyclouridine  105847-66-3   Uracil/*analogs & derivatives Schistosoma mansoni Uridine Phosphorylase/antagonists & inhibitors. J Biol Chem 1988;263(13):6081
5-ethyl-2,2'-anhydrouridine  0   Uridine/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. Drugs Exp Clin Res 1987;13(10):615
1-((2-hydroxy-1-(aminomethyl)ethoxy)methyl)-5-benzyluracil  96328-45-9   Uracil/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. Biochem Pharmacol 1985;34(7):1121
1-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-5-benzyluracil  96328-44-8   Uracil/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. Biochem Pharmacol 1985;34(7):1121
5-benzyloxybenzylacyclouridine  82857-75-8 2,4(1H,3H)-Pyrimidinedione, 1-((2-hydroxyethoxy)methyl)-5-((3-(phenylmethoxy)phenyl)methyl)  Uracil/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. Biochem Pharmacol 1982;31(10):1857
5-benzylacyclouridine  82857-69-0 2,4(1H,3H)-Pyrimidinedione, 1-((2-hydroxyethoxy)methyl)-5-(phenylmethyl)  Uracil/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors 		Biochem Pharmacol 1982;31(10):1857
1-(2'-deoxy-beta-D-glucopyranosyl)thymine  5116-45-0 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-arabino-hexopyranosyl)-5-methyl  Thymidine/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. Cancer Res 1981; 40(3):507
benzylthiouracil  6336-50-1   Thiouracil/*analogs & derivatives Uridine Phosphorylase/antagonists & inhibitors. C R Soc Biol (Paris) 172(4):691;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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