encyclopedia of medical concepts
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Isotretinoin
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Definition
: A topical dermatologic agent that is used in the treatment of ACNE VULGARIS and several other skin diseases. The drug has teratogenic and other adverse effects.
Pharmacological Action
Dermatologic Agents
;
Teratogens
Other names
13-
cis-
Retinoic Acid; Ro 43780; Ro 4 3780; Isotretinoin Zinc Salt, 13 cis Isomer; 13 cis Retinoic Acid; Isotretinoin Zinc Salt, 13-
cis-
Isomer; Roaccutane; Ro 4-
3780; Accutane
Drugs
*
:
ACCUTANE
;
SOTRET
;
MYORISAN
;
AMNESTEEM
;
CLARAVIS
Substance
CAS Registry & name
Categories
Source
Drugs
*
Accutane embryopathy
0
*Abnormalities, Drug-Induced
Isotretinoin/adverse effects.
16-
hydroxyisotretinoin
126532-33-0
Isotretinoin/*analogs & derivatives.
Xenobiotica 1990;20(2):193
13-
(4-
oxoretinoyl)-
beta-
glucuronide
0
Isotretinoin/*analogs & derivatives.
Arch Biochem Biophys 1981;208(2):344