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Tylosin

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Definition: Macrolide antibiotic obtained from cultures of Streptomyces fradiae. The drug is effective against many microorganisms in animals but not in humans.  do not use /biosyn unless by living matter   
Pharmacological Action Anti-Bacterial Agents 		Other names Hydrochloride, Tylosin; Tylosine; Tylosin Tartrate (Salt); Tylosin Hydrochloride; Tylan; Fradizine
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tylvalosin  0   Tylosin/*analogs & derivatives. Vet Rec 2009 Sep 19;165(12):342-5
aivlosin  0   Tylosin/*analogs & derivatives. Avian Dis 2002 Jan-Mar;46(1):215-8
10,11-dihydrodesmycosin  0   Tylosin/*analogs & derivatives. Eur J Pharm Sci. 2003 Apr;18(5):323-8
13-hydroxy-3-dehydroxy-3,12-oxa-desmycosin  0   Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 2002 Sep;55(9):803-13
2,3-didehydrodesmycosin  0   Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 2002 Apr;55(4):427-36
4-'demycarosyl-20-deoxo-20-(di-N-benzylamino)-8a-aza-8a-homotylosin  0   Tylosin/*analogs & derivatives. Chemotherapy 1998 Sep-Oct;44(5):331-6
12,13-epoxydesmycosin  0   Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1997 Oct;50(10):860-5
hexafluorotilmicosin  0   Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1995 Jul;48(7):671-5
4'-deoxy-10,11,12,13-tetrahydrodesmycosin  0   Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1995 Mar;48(3):248-53
para-nitrobenzyl-oxime-tylosine  145144-30-5   Tylosin/*analogs & derivatives Macrolides. J Antimicrob Chemother 1992 Sep;30(3):327-37
23-O-benzyl-5-mycaminosyl-tylonolide  89109-82-0   Tylosin/*analogs & derivatives. J Pharmacobiodyn 1991 Jul;14(7):377-83
3,4'-dideoxy-5O-mycaminosyltylonolide  127521-69-1   Tylosin/*analogs & derivatives Macrolides. J Antibiot (Tokyo) 1992 Jan;45(1):144-6
Sch 37644  122825-61-0 Tylosin, 23-O-acetyl-23-O-de(6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)-, 2A,3-diacetate 4B-(3-methylbutanoate)  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1990;43(9):1131
Sch 38646  122076-87-3 Tylosin, 23-O-acetyl-23-O-de(6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)-12,13-epoxy-12,13-dihydro-, 2A,3-diacetate 4B-(3-methylbutanoate), (12S,13S)  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1990;43(9):1131
19-deformyl-5-O-desosaminyl tylonide  86131-94-4   Tylosin/*analogs & derivatives. FEMS Microbiol Lett 1990;57(1-2):101
TMC 015  85382-81-6   Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1990;43(3):327
19-deformyldesmycosin  78740-70-2 Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-6-de(2-oxoethyl)-6-methyl  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1990;43(3):327
23-amino-O-mycaminosyltylonolide  90494-31-8   Tylosin/*analogs & derivatives. Appl Environ Microbiol 1989;55(6):1507
TMC 016  85382-79-2   Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1989;42(6):903
4''-O-(4-methoxyphenyl)acetyltylosin  103360-00-5   Tylosin/*analogs & derivatives Macrolides. J Antibiot (Tokyo) 1987;40(9):1358
tilmicosin  108050-54-0   Tylosin/*analogs & derivatives.
Pharma Action Anti-Bacterial Agents 		J Antibiot (Tokyo) 1987;40(2):190
tylosin B  11032-98-7   Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1987;40(2):190
tylosin phosphate and bentonite drug combination  1405-53-4   *Bentonite Drug Combinations Tylosin/*analogs & derivatives. Vet Med Nauki 1983;20(5-6):80
FV 82  88154-94-3   *Tylosin *Iron-Dextran Complex *Pyridoxine *Vitamin B 12 Drug Combinations. Vet Med Nauki 1983;20(3-4):40
chimeramycin B  87092-83-9 Tylosin, 23-de((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxy)-9-deoxo-9-((5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-, (9R(2R,5S,6R))  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1983;36(7):927
chimeramycin A  87084-47-7 Tylosin, 23-de((6-deoxy-2,3-di-O-methyl-beta-D-allopyranosyl)oxy)-9-deoxo-9-((5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl)oxy)-, 3-acetate, (9R(2R,5S,6R))  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1983;36(7):927
neotil  85883-86-9 Tylosin, mixt. with neomycin sulfate (salt)  Neomycin Tylosin. Vet Med Nauki 1982;19(6):84
5-O-mycaminosylprotylonolide  81661-90-7 Tylonolide, 20-deoxo-23-deoxy-5-O-(3,6-dideoxy-3-(dimethylamino)-beta-D-glucopyranosyl)  Tylosin/*analogs & derivatives. Biochem Biophys Res Commun 1982;107(2):554
20-deoxorosaranolide  81560-70-5 Tylonolide, 20-deoxo-23-deoxy-12,13-epoxy-12,13-dihydro  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1982;35(2):251
4'-dexydemycarosyltylosin  80241-24-3 Tylosin, 4A-de((2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)oxy)  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1981;34(10):1381
4'-deoxymycaminosyltylonolide  80240-61-5 Tylonolide, 5-O-(3,4,6-trideoxy-3-(dimethylamino)-beta-D-glucopyranosyl)  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1981;34(10):1374
3-acetyl-4''-isovaleryltylosin  63409-12-1   Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1981;34(3):305
protylonolide  74758-60-4 Tylonolide, 20-deoxo-23-deoxy  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1980;33(8):915; J Antibiot (Tokyo) 1982;35(2):251
micarosyl protylonolide  75399-55-2 Tylonolide, 20-deoxo-23-deoxy-5-O-(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1980;33(8):913
9-acetylmidecamycin  35457-78-4 leucomycin V, 9-acetate 3,4(B)-dipropanoate  Tylosin/*analogs & derivatives. J Antibiot (Tokyo) 1980;33(1):61
staphcoccomycin  73047-31-1 Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-2A-deoxy-12,13-epoxy-12,13-dihydro  Tylosin/*analogs & derivatives Macrolides. J Antibiot (Tokyo) 1979;32(12):1248
Tylavit-sulfa  65702-93-4 tylosin, mixt. with 4-amino-N-(4,6-dimethyl-2- pyrimidinyl)benzenesulfonamide & retinol  *Sulfamethazine *Vitamin A *Tylosin Drug Combinations. Med Weteryn 32(11):684;1976
tylonolide hemiacetal  61219-81-6 (4R-(4R*,5S*,6S*,7R*,9R*,11E,13E,15S*,16R*))- 16-ethyl-4,6-dihydroxy-15-(hydroxymethyl)-5,9,13- trimethyl-2,10-dioxooxacyclohexadeca-11,13-diene-7- acetaldehyde, cyclic 5,20-hemiacetal  Tylosin/*analogs & derivatives. J Am Chem Soc 98(24):7874;1976
angolamycin  1402-83-1   Tylosin/*analogs & derivatives. J Antibiotics 25(8):480;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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