encyclopedia of medical concepts
ψ
ψ
ψ
ψ
ψ
ψ
Heparin Cofactor II
More information
in Books
or on
Definition
: A sulfated plasma protein with a MW of approximately 66kDa that resembles ANTITHROMBIN III. The protein is an inhibitor of thrombin in plasma and is activated by dermatan sulfate or heparin. It is a member of the serpin superfamily.
Pharmacological Action
Antithrombins
;
Serine Proteinase Inhibitors
Other names
Serpin D1; Heparin Co Factor II; Protease Inhibitor Leuserpin 2; Heparin Cofactor 2; Heparin Co-
Factor II; Leuserpin 2
Substance
CAS Registry & name
Categories
Source
Drugs
*
Serpind1 protein, rat
0
*Heparin Cofactor II.
Serpind1 protein, mouse
0
*Heparin Cofactor II.
intimatan
0
Dermatan Sulfate/*analogs & derivatives
Thrombin/antagonists & inhibitors
Heparin Cofactor II/agonists.
Thromb Res 2000 Sep 15;99(6):603-12
SERPIND1 protein, human
0
*Heparin Cofactor II.
Nucleic Acids Res 1986;14(2):1073