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Serine Proteinase Inhibitors
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Definition
: Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES.
DF: SERINE PROTEINASE INHIB
See Also
Serpins
Examples
Antithrombins
;
Trypsin Inhibitors
Other names
Serine Proteinase Inhibitors, Exogenous; Serine Proteinase Inhibitors, Endogenous; Serine Proteinase Antagonists; Serine Protease Inhibitors; Serine Endopeptidase Inhibitors; Serine Protease Inhibitors, Exogenous; Serine Protease Inhibitors, Endogenous
Substances having this pharmacologic action:
subtilisin inhibitor protein, Streptomyces
;
tissue-factor-pathway inhibitor 2
;
purpurogallin
;
methoxysuccinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone
;
eglin proteinase inhibitors
;
urokinase inhibitor
;
benzamidine
;
nafamostat
;
Eco protein, E coli
;
phenylalanyl-prolyl-arginine-chloromethyl ketone
;
rosmarinic acid
;
cholesteryl sulfate
;
DAPI
;
4-(2-aminoethyl)benzenesulfonylfluoride
;
chymostatin
;
Secretory Leukocyte Peptidase Inhibitor
;
Serpin E2
;
ITIH4 protein, human
;
4-aminobenzamidine
;
Angiotensinogen
;
alpha-2-Antiplasmin
;
Gabexate
;
Plasminogen Activator Inhibitor 1
;
Plasminogen Activator Inhibitor 2
;
Protein C Inhibitor
;
Tosyllysine Chloromethyl Ketone
;
Tosylphenylalanyl Chloromethyl Ketone
;
Serpins
;
Heparin Cofactor II
;
Plasminogen Inactivators
;
alpha 1-Antichymotrypsin
;
alpha 1-Antitrypsin
;
Aprotinin
;
Amino Acid Chloromethyl Ketones
;
inter-alpha-inhibitor
;
SPINT2 protein, human
;
SPINK7 protein, human
;
chymotrypsin inhibitor 2
;
neuroserpin
;
SERPIN-B5
;
DX 9065a
;
ONO 5046
;
ICI 200355
;
tick anticoagulant peptide
;
L 658758
;
4-(2-succinimidoethylthio)phenyl 4-guanidinobenzoate
;
lipoprotein-associated coagulation inhibitor
;
3,4-dichloroisocoumarin
Substance
CAS Registry & name
Categories
Source
Drugs
*
TIL-
1 protein, Ancylostoma duodenale
0
*Helminth Proteins
Serine Proteinase Inhibitors.
Parasitol Res 2011 Feb;108(2):287-95
Spink9 protein, human
0
*Proteinase Inhibitory Proteins, Secretory
Serine Proteinase Inhibitors.
PLoS One 2009;4(2):e4372
KAZ1 protein, Drosophila
0
*Drosophila Proteins
Serine Proteinase Inhibitors.
Eur J Biochem 1999 Nov;266(1):282-92
ASPI-
2 protein, Ascaris suum
0
*Insect Proteins
Pancreatic Elastase
Serine Proteinase Inhibitors.
Mol Biochem Parasitol 1999 Jul 30;102(1):79-89
bdellastasin
0
*Insect Proteins
Fibrinolysin/antagonists & inhibitors
Serine Proteinase Inhibitors.
J Mol Biol 1999 Oct 15;293(1):93-106
SPINK5 protein, human
0
*Proteinase Inhibitory Proteins, Secretory
Serine Proteinase Inhibitors.
J Biol Chem 1999 Jul 30;274(31):21499-502
allyl-
6-
(acetoxyethyl)-
penem-
3-
carboxylate
0
*Carboxylic Acids
*Lactams
Serine Proteinase Inhibitors.
Nature 1998 Nov 12;396(6707):186-90
tPA stop
0 2,7-
bis-
(4-
amidino-
benzylidene)-
cycloheptan-
1-
one dihydrochloride
*Cycloheptanes
Tissue Plasminogen Activator/antagonists & inhibitors
Serine Proteinase Inhibitors.
J Cereb Blood Flow Metab. 2004 Oct;24(10):1153-9; Neuron 1998 Oct;21(4):813-25
Pcsk1n protein, mouse
0
*Nerve Tissue Proteins
Serine Proteinase Inhibitors.
Neuroendocrinology 1998 Mar;67(3):190-6
GR 133687
0
*Lactones
*Triterpenes
Thrombin/antagonists & inhibitors
Serine Proteinase Inhibitors.
Biochemistry 1998 May 12;37(19):6645-57
GR 133686
0
*Lactones
*Triterpenes
Thrombin/antagonists & inhibitors
Serine Proteinase Inhibitors.
Biochemistry 1998 May 12;37(19):6645-57
Spin2b protein, rat
0
*Serpins
*Nuclear Proteins
Serine Proteinase Inhibitors.
Eur J Biochem 1995 Aug 1;231(3):620-7
anticoagulant protein, Ancylostoma caninum
0
*Helminth Proteins
Serine Proteinase Inhibitors.
Proc Natl Acad Sci U S A 1995 Jun 20;92(13):6152-6
SIL8 protein, Streptomyces virginiae
0
*Bacterial Proteins
Serine Endopeptidases
Serine Proteinase Inhibitors.
Eur J Biochem 1994 Dec 1;226(2):627-32