Gabexate (definition)

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Gabexate

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Definition: A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.

Pharmacological Action Anticoagulants; Serine Proteinase Inhibitors

Other names Monomethanesulfonate, Gabexate; Methanesulfonate, Gabexate; Mesylate, Gabexate; Mesilate, Gabexate; Gabexate Monomethanesulfonate, 14C Labeled Cpd; Gabexate Monomethanesulfonate, 14C-Labeled Cpd; Gabexate Monomethanesulfonate; Gabexate Methanesulfonate; Gabexate Mesylate; Gabexate Mesilate; Foy

Substance	CAS Registry & name	Categories	Source	Drugs*
FOY 305	59721-28-7	Gabexate/analogs & derivatives. Pharma Action* Protease Inhibitors ; Trypsin Inhibitors	Gan 1981;72(6):959

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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