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Receptors, Very Late Antigen

More information in Books or onNLM PubMed
Definition: Members of the integrin family appearing late after T-cell activation. They are a family of proteins initially identified at the surface of stimulated T-cells, but now identified on a variety of cell types. At least six VLA antigens have been identified as heterodimeric adhesion receptors consisting of a single common beta-subunit and different alpha-subunits.  DF: RECEPT VLA   
Examples Integrin alpha1beta1; Integrin alpha2beta1; Integrin alpha3beta1; Integrin alpha4beta1; Integrin alpha5beta1; Integrin alpha6beta1
Other names VLA Protein Complex; Receptors, VLA; Protein Complex, VLA; Differentiation Antigens, VLA; Antigens, VLA Differentiation; Antigens, VLA Activation; Activation Antigens, VLA; Very Late Antigen Receptors; Very Late Activation Antigen Receptors; VLA Receptors; VLA Differentiation Antigens; VLA Activation Antigens; Receptors, Very Late Activation Antigen; Receptor, Very Late Antigen
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CDw49d  0   *Integrin alpha Chains Receptors, Very Late Antigen. J Immunol 1990;144(3):777

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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