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HIV Protease Inhibitors

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Definition: Inhibitors of HIV PROTEASE, an enzyme required for production of proteins needed for viral assembly.  DF: HIV PROTEASE INHIB    Other names Protease Inhibitors, HIV; Inhibitors, HIV Protease
Substances having this pharmacologic action: Nelfinavir; Lopinavir; Saquinavir; Ritonavir; Indinavir; atazanavir; fosamprenavir; darunavir; amprenavir; kynostatin 272; Abbott 77003; DMP 323
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
KNI 10033  0   *Isoquinolines *Thiazoles HIV Protease Inhibitors/antagonists & inhibitors. Chem Biol Drug Des 2007 Jun;69(6):413-22
PNU 96988  0   *Pyrones HIV Protease Inhibitors. J Pharm Biomed Anal 1999 Mar;19(3-4):399-411
JE 2147  0   *Dipeptides *Phenylbutyrates HIV Protease Inhibitors. Proc Natl Acad Sci USA 1999 Jul 20;96(15):8675-80
AG 1284  0   Organic Chemicals HIV Protease Inhibitors. AIDS Patient Care 1994 Feb;8(1):42
pepstatin  39324-30-6   *Pepstatins HIV Protease Inhibitors.
Pharma Action Antimalarials ; Protease Inhibitors
FEBS Lett 1981;128(1):63

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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