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Phosphotransferases (Phosphomutases)

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Definition: A group of enzymes that catalyze an intramolecular transfer of a phosphate group. It has been shown in some cases that the enzyme has a functional phosphate group, which can act as the donor. These were previously listed under PHOSPHOTRANSFERASES (EC 2.7.-). (From Enzyme Nomenclature, 1992) EC 5.4.2.  DF: note short X ref   
Examples Bisphosphoglycerate Mutase; Phosphoglucomutase; Phosphoglycerate Mutase 		Other names Phosphomutases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
phosphomannomutase 2, human  EC 5.4.2.8   *Phosphotransferases (Phosphomutases). Nat Genet 1997 May;16(1):88-92
Pmm2 protein, mouse  EC 5.4.2.8   *Phosphotransferases (Phosphomutases). Gene 2001 May 30;270(1-2):53-9
beta-phosphoglucomutase, Lactococcus lactis  EC 5.4.2.6   *Phosphotransferases (Phosphomutases). Biochemistry 2006 Jun 27;45(25):7818-24
PgmG protein, Sphingomonas paucimobilis  EC 5.4.2.-   *Bacterial Proteins *Multienzyme Complexes *Phosphotransferases (Phosphomutases). Appl Environ Microbiol 2000 May;66(5):2252-8
carboxyphosphonoenolpyruvate phosphonomutase  EC 5.4.2.-   *Phosphotransferases (Phosphomutases). J Bacteriol 1990;172(6):3066
phosphoenolpyruvate mutase  EC 5.4.2.9   *Phosphotransferases (Phosphomutases). Nature 1988;335(29):457
phosphomannomutase  EC 5.4.2.8   *Phosphotransferases (Phosphomutases) Acyl Carrier Protein. J Bacteriol 1987;169(7):3224
dTDPglucose 4,6-dehydratase  EC 4.2.1.46   *Hydro-Lyases Phosphotransferases (Phosphomutases) ATP-Binding Cassette Transporters. J Biol Chem 245(1):8;1970; J Biol Chem 252(22):8113;1977
phosphoacetylglucosamine mutase  EC 5.4.2.3   *Phosphotransferases (Phosphomutases). Anal Biochem 85:533;1978; Biochim Biophys Acta 451:408;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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