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Vaccines, Conjugate

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Definition: Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.  "induce antibody formation in people not responsive to polysaccharide alone"; semisynthetic vaccines; coord NIM with specific vaccine (IM)    Other names Conjugate Vaccines
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Act-Hib vaccine  0   *Haemophilus Vaccines Vaccines, Conjugate. Br J Haematol. 2012 Feb;156(3):407-9
HibMenCY-TT vaccine  0   *Polysaccharides, Bacterial *Tetanus Toxoid *Haemophilus Vaccines Vaccines, Conjugate. Expert Rev Vaccines. 2011 Jul;10(7):941-50.
prevenar13  0   *Pneumococcal Vaccines Vaccines, Conjugate. MMWR Morb Mortal Wkly Rep. 2010 Mar 12;59(9):258-61.
synflorix  0   *Pneumococcal Vaccines Vaccines, Conjugate. Vaccine. 2009 Sep 25;27(42):5748-54.
MenACWY-D vaccine  0   *Meningococcal Vaccines Vaccines, Conjugate. Int J Infect Dis. 2010 Oct;14(10):e868-75.
MenACWY-CRM vaccine  0   *Meningococcal Vaccines Vaccines, Conjugate. Int J Infect Sci 2010 Oct;14(10):e868-75
PHiD-CV vaccine  0   *Pneumococcal Vaccines Vaccines, Conjugate. Pediatr Infect Dis J 2009 Apr;28(4 Suppl):S109-1
diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine  0   *Poliovirus Vaccine, Inactivated *Diphtheria-Tetanus-Pertussis Vaccine *Hepatitis B Vaccines *Haemophilus Vaccines Vaccines, Conjugate. Vaccine 2009 Apr 28;27(19):2540-7
diphtheria-tetanus-five component acellular pertussis-inactivated poliomyelitis -Haemophilus influenzae type b conjugate vaccine  0   *Poliovirus Vaccine, Inactivated *Diphtheria-Tetanus-Pertussis Vaccine *Haemophilus Vaccines Vaccines, Conjugate. Int J Infect Dis 2007 Mar;11(2):129-36
10-valent pneumococcal vaccine  0   *Pneumococcal Vaccines Vaccines, Conjugate. Salud Publica Mex 2009 Jan-Feb;51(1):4
13-valent pneumococcal vaccine  0   *Pneumococcal Vaccines Vaccines, Conjugate. Salud Publica Mex 2009 Jan-Feb;51(1):4
Hib-MenCY-TT vaccine  0   *Tetanus Toxoid *Haemophilus Vaccines Vaccines, Conjugate. Vaccine 2007 Dec 12;25(21):8487-99
MenACWY  0   *Meningococcal Vaccines Vaccines, Conjugate. JAMA 2008 Jan 9;299(2):173-84
Hiberix  0   *Haemophilus Vaccines Vaccines, Conjugate. Med Dosw Mikrobiol 1998;50(3-4):223-8
MCP-CRM197 conjugate vaccine  0   *Meningococcal Vaccines Vaccines, Conjugate. Infect Immun 2005 Dec;73(12):8256-65
shiga toxin 2 B-subunit-keyhole limpet hemocyainin conjugate vaccine  0   *Bacterial Vaccines Vaccines, Conjugate. Infect Immun 2005 Oct;73(10):6523-9
globo H-KLH vaccine  0   *Cancer Vaccines Vaccines, Conjugate. Vaccine 2005 May 2;23(24):3114-22
MUC-2-KLH vaccine  0   *Cancer Vaccines Vaccines, Conjugate. Vaccine 2005 May 2;23(24):3114-22
MC-4 vaccine  0   *Meningococcal Vaccines Vaccines, Conjugate. Pediatr Infect Dis J 2005 Feb;24(2):132-6
Menactra  0   *Meningococcal Vaccines Vaccines, Conjugate. JAMA 2005 Mar 23;293(12):1433-4
meningococcal type B conjugate vaccine  0   *Meningococcal Vaccines Vaccines, Conjugate. Anal Biochem 2004 Apr 15;327(2):261-70
streptococcal polysaccharide type II-tetanus toxoid conjugate vaccine  0   *Polysaccharides, Bacterial *Tetanus Toxoid Vaccines, Synthetic Vaccines, Conjugate. J Infect Dis 2000 Oct;182(4):1129-38
serogroup C meningococcal conjugate vaccine  0   *Meningococcal Vaccines Neisseria meningitidis Vaccines, Conjugate. JAMA 2000 Jun 7;283(21):2795-801
GD3-lactone-KLH  0   *Gangliosides Vaccines, Conjugate. Int J Cancer 2000 Mar 1;85(5):659-66
morphine-6-succinyl-bovine serum albumin  0   *Morphine *Serum Albumin, Bovine Morphine Dependence Vaccines, Conjugate. Biotechnol Appl Biochem 1999 Oct;30 ( Pt 2):139-46
cholera toxin B-insulin conjugate  0   *Cholera Toxin *Insulin Vaccines, Conjugate. Diabetes 1999 Nov;48(11):2150-6
globo H-keyhole limpet hemocyanin QS-21 vaccine  0   *Cancer Vaccines Vaccines, Conjugate. Proc Natl Acad Sci U S A 1999 May 11;96(10):5710-5
group B streptococcal type III capsular polysaccharide-tetanus toxoid vaccine  0   *Bacterial Capsules *Streptococcal Vaccines Vaccines, Synthetic Vaccines, Conjugate. J Infect Dis 1997 May;175(5):1237-9
five-valent pneumococcal conjugate vaccine  0   *Pneumococcal Vaccines Vaccines, Conjugate. Pediatrics 1997 Apr;99(4):575-80
COMVAX  0   *Hepatitis B Vaccines *Haemophilus Vaccines Vaccines, Synthetic Vaccines, Conjugate. MMWR Morb Mortal Wkly Rep 1997 Feb 7;46(5):107-9
Tetracel  0   *Diphtheria-Tetanus-Pertussis Vaccine *Haemophilus Vaccines Vaccines, Conjugate. Dev Biol Stand 1996;87:269-75
heptavalent pneumococcal conjugate vaccine  0   *Pneumococcal Vaccines Vaccines, Conjugate. J Pediatr 1996 May;128(5 Pt 1):649-53
sialyl-Tn antigen-keyhole-limpet hemocyanin conjugate  0   *Cancer Vaccines Glycoconjugates Hemocyanin Antigens, Tumor-Associated, Carbohydrate Vaccines, Conjugate. Glycobiology 1995 Dec;5(8):759-64
PncOMPC vaccine  0   *Pneumococcal Vaccines *Meningococcal Vaccines Vaccines, Conjugate. J Infect Dis 1995 Nov;172(5):1273-8
streptococcal polysaccharide-tetanus toxoid conjugate vaccine  0   *Polysaccharides, Bacterial *Tetanus Toxoid Vaccines, Conjugate. J Infect Dis 1995 Apr;171(4):879-84
diphtheria-tetanus-pertussis-haemophilus b conjugate vaccine  0   *Diphtheria-Tetanus-Pertussis Vaccine *Haemophilus Vaccines Vaccines, Conjugate. MMWR Morb Mortal Wkly Rep 1993 Apr 23;42(15):296-8
Brucella melitensis 16M conjugate vaccine  0   *Brucella Vaccine *Serum Albumin, Bovine Brucella Vaccines, Conjugate. Vaccine 1991 Dec;9(12):896-900
IgG hinge protein-gastrin 17 (2-17)  0   *Gastrins *Immunoglobulin G *Peptide Fragments Vaccines, Conjugate. Int J Pept Protein Res 1991;37(2):90
gastrin 34 (1-14)-IgG hinge protein-gastrin 17 (2-17)  133515-75-0   *Gastrins *Immunoglobulin G *Peptide Fragments Vaccines, Conjugate. Int J Pept Protein Res 1991;37(2):90
Vaxstrate  0   *Gonadotropin-Releasing Hormone *Ovalbumin Vaccines, Conjugate. Aust J Biotechnol 1990;4(3):166
Haemophilus influenzae-type b polysaccharide-Neisseria meningitidis outer membrane protein conjugate vaccine  0   *Bacterial Outer Membrane Proteins *Polysaccharides, Bacterial *Haemophilus Vaccines Vaccines, Conjugate. Contrib Microbiol Immunol 1989;10:125
human chorionic gonadotropin-cholera toxoid conjugate  0   *Cholera Toxin *Chorionic Gonadotropin *Luteinizing Hormone Vaccines, Conjugate. Vaccine 1989;7(2):129
Pseudomonas aeruginosa O polysaccharide-toxin A conjugate vaccine  0   *Bacterial Toxins *Pseudomonas Vaccines Polysaccharides, Bacterial Pseudomonas aeruginosa Vaccines, Conjugate O Antigens. Microb Pathog 1989;6(1):75
Haemophilus influenza type b polysaccharide vaccine-tetanus toxin conjugate  0   *Tetanus Toxoid *Haemophilus Vaccines Vaccines, Conjugate. J Pediatr 1988;112(5):695
Streptococcus mutans polysaccharide-saliva receptor protein conjugate  0   *Bacterial Proteins *Bacterial Vaccines Polysaccharides, Bacterial Streptococcus mutans Vaccines, Conjugate. Vaccine 1987;5(1):39
Pseudomonas aeruginosa O-polysaccharide-tetanus toxoid conjugate  0   *Tetanus Toxoid *Pseudomonas Vaccines Vaccines, Conjugate O Antigens. Vaccine 1987;5(1):33
Haemophilus influenzae type b-polysaccharide vaccine-diphtheria toxoid conjugate  0   *Diphtheria Toxoid *Haemophilus Vaccines Vaccines, Conjugate. Dev Biol Stand 1986;65:113
human chorionic gonadotropin-tetanus toxoid  0   *Tetanus Toxoid *Glycoprotein Hormones, alpha Subunit *Chorionic Gonadotropin, beta Subunit, Human Vaccines, Conjugate. Contraception 1982;25(4):421

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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