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Gangliosides

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Definition: A subclass of ACIDIC GLYCOSPHINGOLIPIDS. They contain one or more sialic acid (N-ACETYLNEURAMINIC ACID) residues. Using the Svennerholm system of abbrevations, gangliosides are designated G for ganglioside, plus subscript M, D, or T for mono-, di-, or trisialo, respectively, the subscript letter being followed by a subscript arabic numeral to indicated sequence of migration in thin-layer chromatograms. (From Oxford Dictionary of Biochemistry and Molecular Biology, 1997)     
Examples G(M1) Ganglioside; G(M2) Ganglioside; G(M3) Ganglioside 		Other names Sialoglycosphingolipids
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2,3-sialylparagloboside  0   *Gangliosides. J Biochem 2010 Apr;147(4):459-62
1-O-(9-O-methyl-(N-acetyl-alpha-D-neuraminosyl)-(2-6)-beta-D-glucopyranosyl)ceramide  0   *Gangliosides. Chem Pharm Bull (Tokyo) 2008 May;56(5):734-7
ganglioside GP-3, Asterina pectinifera  0   *Gangliosides. Chem Pharm Bull (Tokyo) 2006 Mar;54(3):287-91
N-deacetylsialyl Lewis X ganglioside  0   *Gangliosides Lewis Blood-Group System. Carbohydr Res. 2002 Nov 19;337(21-23):2111-7
1-O-((fucopyranosyl-(1-11)-(N-glycolylneuraminosyl)neuraminosyl)-(2-4)-(N-aetylneuraminosyl)-(2-6)-glucopyranosyl)ceramide  0   *Gangliosides. Chem Pharm Bull (Tokyo) 2001 Apr;49(4):447-52
1-O-((N-glycolylneuraminosyl)-(2-4)-(N-acetylneuraminosyl)-(2-6)glucopyranosyl)ceramide  0   *Gangliosides. Chem Pharm Bull (Tokyo) 2001 Apr;49(4):447-52
1-O-((N-glycolylneuraminosyl)-(2-6)-glucopyranosyl)ceramide  0   *Gangliosides. Chem Pharm Bull (Tokyo) 2001 Apr;49(4):447-52
N-acetylneuraminic acid-(2,3)-Gal C-disaccharide  0   *Alkenes *Disaccharides Gangliosides. J Org Chem 2001 Jun 15;66(12):4250-60
CI 22  0   *Gangliosides. Biochem Biophys Res Commun. 2000 Oct 5;276(3):1210-6
TMS 42  0   *Gangliosides. Biochem Biophys Res Commun. 2000 Oct 5;276(3):1210-6
HPG-7 ganglioside  0   *Gangliosides. Chem Pharm Bull (Tokyo) 2000 Jan;48(1):157-9
GD3-lactone-KLH  0   *Gangliosides Vaccines, Conjugate. Int J Cancer 2000 Mar 1;85(5):659-66
IV(4)GalNAcGgOse(4)Cer  0   *Gangliosides. Glycobiology 2000 Jan;10(1):1-9
9-O-acetyl-GD1b ganglioside  0   *Gangliosides Polyradiculoneuropathy. J Neuroimmunol 1996 May;66(1-2):95-101
sialyl dimeric Le(X) glycononaosyl ceramide  0   *Gangliosides. Glycoconj J 1996 Apr;13(2):203-11
V(6)Neu5AciGb(5)Cer  0   *Gangliosides. Carbohydr Res 1996 Apr 30;284(2):179-90
V(3)Neu5AciGb(5)Cer  0   *Gangliosides. Carbohydr Res 1996 Apr 30;284(2):179-90
GM2-1 ganglioside  0   *Gangliosides Autoantigens. Diabetologia 1995 Sep;38(9):1117-21
GalNAc-G(D1a)(Neu5Gc-Neu5Ac)  0   *Gangliosides. Eur J Biochem 1995 Dec 15;234(3):786-93
GalNAc-G(D1a)(Neu5Ac-Neu5Gc)  0   *Gangliosides. Eur J Biochem 1995 Dec 15;234(3):786-93
7-O-acetyl-GD3 ganglioside  0   *Gangliosides. J Biol Chem 1995 Dec 15;270(50):30173-80
pyrenyldodecanoyl-GM3  0   *Gangliosides. Chem Phys Lipids 1995 Aug 25;77(2):253-60
sialyl Lewis(x) ganglioside  0   *Gangliosides Lewis Blood-Group System. Biosci Biotechnol Biochem 1995 Jun;59(6):1091-4
di-sialyl Le(a)  0   *Gangliosides Lewis Blood-Group System. Cancer Res 1995 May 1;55(9):1869-74
KDN-Lewis X ganglioside  0   *Gangliosides. Carbohydr Res 1994 Jun 17;259(2):201-18
N-glycolylneuraminic acid-isooctaosylceramide  0   *Gangliosides. Arch Biochem Biophys 1994 May 1;310(2):373-84
disialosyl galactosyl globoside  71764-07-3   *Gangliosides. J Biol Chem 1994 Feb 25;269(8):5644-52
9-O-acetyl GT2  152443-13-5   *Gangliosides. J Biochem (Tokyo) 1993 Oct;114(4):459-62
WILD 20  152784-11-7 beta-D-Glucopyranoside, 2--amino-3-hydroxy-4-eicosenyl O-beta-D-galactopyranosyl-(1-3)-O-2-amino-2-deoxy-beta-D-galactopyranosyl-(1-4)-O-(alpha-neuraminosyl-(2-3))-O-beta-D-galactopyranosyl-(1-4)-, (R-(R*,S*-(E)))  *Gangliosides. Eur J Pharmacol 1993 Aug 2;248(2):175-83
GT1aalpha ganglioside  141255-28-9   *Gangliosides Antigens, Surface. Brain Res 1993 Sep 24;623(1):83-8
GQ1balpha ganglioside  143476-26-0   *Gangliosides Antigens, Surface. Brain Res 1993 Sep 24;623(1):83-8
dimeric Le(a) antigen, human  0   *Gangliosides Tumor Markers, Biological Antigens, Tumor-Associated, Carbohydrate. Cancer Immunol Immunother 1993 Sep;37(4):245-50
tetrasialoganglioside GQ1c  0   *Gangliosides. Brain Res 1983 Oct 24;277(1):155-8
tetrasialoganglioside GQ1b  0   *Gangliosides. Eur J Immunol 1981 Apr;11(4):347-9
IV(3)-NeuAc-LcOse4Cer  103842-51-9   *Gangliosides Epitopes. Cancer Res 1993 Jan 1;53(1):120-6
IV(3)-NeuAc-III(6)-NeuAc-LcOse4Cer  146358-72-7   *Gangliosides Epitopes. Cancer Res 1993 Jan 1;53(1):120-6
ganglioside, GD1c  104137-85-1 Ganglioside GD1c  *Gangliosides. J Biochem (Tokyo) 1991;110(2):274
sperm ganglioside 2  0   *Gangliosides. J Biol Chem 1991; 266(32):21929
sperm ganglioside 1  0   *Gangliosides. J Biol Chem 1991;266(32):21929
ganglioside GD3 gangliosidol congener  0   *Gangliosides. Int J Cancer 1991;48(3):379
ganglioside GD3 amide congener  0   *Amides *Gangliosides. Int J Cancer 1991;48(3):379
ganglioside T1  76688-83-0   *Gangliosides. J Biochem 1990;108(2):185
ganglioside M5  77322-99-7   *Gangliosides. J Biochem 1990;108(2):185
ganglioside GM4-2  129069-15-4   *Gangliosides. J Biochem (Tokyo) 1990;107(6):868
ganglioside GM4-1  129069-16-5   *Gangliosides. J Biochem (Tokyo) 1990;107(6):868
sialyl Le(a) ganglioside  91847-18-6   *Gangliosides Lewis Blood-Group System Tumor Markers, Biological Antigens, Tumor-Associated, Carbohydrate. Int J Cancer 1990;45(6):1204
gangliosidepentaosylceramide  106828-81-3   *Gangliosides. Biomed Chromatogr 1990;4(2):70
ganglioside GD1b dilactone  128907-30-2   *Gangliosides *Lactones. Carbohydr Res 1989;195(1):51
ganglioside A2B5  0   *Gangliosides. Neurosci Lett 1989;107(1-3):245
GQ1 ganglioside  62010-39-3   *Gangliosides. Comp Biochem Physiol (B) 1979;63(4):527
GalNAc-3'-isoL(M1) ganglioside  122932-83-6   *Gangliosides. J Biol Chem 1989;264(21):12122
(N-acetylneuraminosyl-(2--8)-N-glycolylneuraminic acid)gangliotetraosylceramide  121382-26-1   *Gangliosides. Acta Biochim Pol 1988;35(3):387
ganglioside, GD1b-lactone  84861-74-5 Ganglioside GD1b, lactone  *Gangliosides *Lactones. J Neurochem 1989;52(5):1401
ganglioside GD1a dilactone  120112-40-5   *Gangliosides *Lactones. Carbohydr Res 1988;182(1):31
GD3 lactone II  119912-76-4   *Gangliosides. J Biol Chem 1989;264(6):3478
GD3 lactone I  119912-77-5   *Gangliosides. J Biol Chem 1989;264(6):3478
ganglioside GT1b-bovine serum albumin complex  0   *Gangliosides *Serum Albumin, Bovine. J Biol Chem 1989;264(3):1671
2-6-N-acetylneuraminyl-1-4-galactosyl-1-3-N-acetylglucosyl-1-4-galactosyl-1-glucosylceramide  71833-54-0   *Gangliosides. FEBS Lett 1988;233(1):134
2-3-N-acetylneuraminyl-1-3-galactosyl-1-3-N-acetylglucosyl-1-4-galactosyl-1-glucosylceramide  97047-95-5   *Gangliosides. FEBS Lett 1988;233(1):134
disialosyl Le(a)  104220-70-4   *Gangliosides. Nippon Hinyokika Gakkai Zasshi 1987;78(11):1878
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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