encyclopedia of medical concepts
ψ 
ψ 
ψ 

Receptors, Mineralocorticoid

More information in Books or onNLM PubMed
Definition: Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone.  coord IM with specific mineralocorticoid (IM); DF: RECEPT MINERALOCORTICOID   
Examples Receptors, Aldosterone 		Other names Receptors, Mineralocorticoids; Receptors, Corticoid Type I; Receptors, Corticoid I; Mineralocorticoid Receptor; Corticoid Type I Receptors; Corticoid I Receptor; Mineralocorticoid Receptors; Receptor, Mineralocorticoid; Receptor, Corticoid I; Mineralocorticoids Receptors; Corticoid I Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
6-(1-(4-fluoro-2-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)-2H-1,4-benzoxazin-3(4H)-one  0   *Pyrazoles *Benzoxazines Receptors, Mineralocorticoid/antagonists & inhibitors. J Med Chem. 2011 Dec 22;54(24):8616-31.
N-4,4-dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-ylthiophene-2-sulfonamide  0   *Sulfonamides *Benzoxazines Receptors, Mineralocorticoid/antagonists & inhibitors. J Pharmacol Sci 2011;115(3):346-53
NR3C2 protein, human  0   *Receptors, Mineralocorticoid. J Pediatr Endocrinol Metab. 2011;24(7-8):555-9
de-O-methyllasiodiplodin  0   *Macrolides Lipase/antagonists & inhibitors Receptors, Mineralocorticoid/antagonists & inhibitors. Bioorg Med Chem Lett 2006 Aug 15;16(16):4205-8
N-(3-(1-cyclopropyl-1-(2,4-difluorophenyl)ethyl)-1H-indol-7-yl)methanesulfonamide  0   *Indoles *Sulfonamides Receptors, Mineralocorticoid/antagonists & inhibitors. J Med Chem 2007 Dec 27;50(26):6443-5
spironolactone receptor  0   *Receptors, Mineralocorticoid. Biochem Pharmacol 1983;32(9):1479

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy