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Cystic Fibrosis Transmembrane Conductance Regulator

More information in Books or onNLM PubMed
Definition: A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum Genet 1994;93(4):364-8)  a chloride channel; DF: note short X ref    Other names Protein, CFTR; CFTR Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Gpact-11a compound  0   *Purines *Pyrimidines Cystic Fibrosis Transmembrane Conductance Regulator/agonists. Eur Respir J 2010 Aug;36(2):311-22
CFTR protein, human  0   *Cystic Fibrosis Transmembrane Conductance Regulator.
cystic fibrosis transmembrane conductance regulator delta F508  0   *Cystic Fibrosis Transmembrane Conductance Regulator Mutation. Am J Physiol 1995 Apr;268(4 Pt 1):L615-24
YCF1 protein, S cerevisiae  0   *ATP-Binding Cassette Transporters *Saccharomyces cerevisiae Proteins Cystic Fibrosis Transmembrane Conductance Regulator. J Biol Chem 1994 Sep 9;269(36):22853-7
FtsE protein, E coli  106178-03-4   *ATP-Binding Cassette Transporters *Cystic Fibrosis Transmembrane Conductance Regulator *Escherichia coli Proteins. Mol Gen Genet 1992 Jul;234(1):121-8
cystic fibrosis transmembrane conductance regulator (505-511)  146289-28-3   *Peptide Fragments *Cystic Fibrosis Transmembrane Conductance Regulator. J Biol Chem 1992 Apr 25;267(12):8411-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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