Definition: Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)
antibodies inhibiting reaction between antigen and other antibodies or sensitized T-lymphocytes: not for any antibody reaction to an antigen (
Pharmacological ActionImmunologic Factors
Other names Enhancing Antibodies; Blocking Antibodies; Antibodies, Enhancing
