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Integrases

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Definition: Recombinases that insert exogenous DNA into the host genome. Examples include proteins encoded by the POL GENE of RETROVIRIDAE and also by temperate BACTERIOPHAGES, the best known being BACTERIOPHAGE LAMBDA.  HIV INTEGRASE is also available   
Examples Transposases 		Other names Integrase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
GSK 501015  0   *Pyrones Integrases. J Virol 2009 Aug;83(15):7706-17
XerD protein, E coli  EC 2.7.7.-   *Integrases *Escherichia coli Proteins.
XerC protein, E coli  0   *Integrases *Escherichia coli Proteins.
ILG1 protein, E coli  EC 2.7.7.-   *Integrases *Escherichia coli Proteins Biological Markers. Mol Med 2002 Jul;8(7):405-16
SSV1 integrase  EC 2.7.7.-   *Integrases. J Biol Chem 2002 May 10;277(19):16758-67
InTI2 protein, E coli  EC 2.7.7.-   *Integrases *Escherichia coli Proteins. J Bacteriol 2002 Mar;184(6):1712-21
integron integrase IntI1  EC 2.7.7.-   *Integrases. J Bacteriol 1998 Oct;180(20):5437-42
STR246N protein, Nicotiana tabacum  0   *Plant Proteins *Integrases. Plant Mol Biol 1994 Oct;26(1):515-21
fimB protein, E coli  0   *DNA-Binding Proteins *Integrases *Escherichia coli Proteins DNA Nucleotidyltransferases Pili, Sex. Microb Pathog 1993 Jan;14(1):33-43
HP1 integrase  125724-60-9   *Integrases DNA Transposable Elements. J Bacteriol 1989;171(8):4232
Cre recombinase  EC 2.7.7.-   *Integrases. J Mol Biol 1985;181(3):351

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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