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Losartan

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Definition: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.     
Pharmacological Action Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Antihypertensive Agents 		Other names Salt, Losartan Monopotassium; Potassium, Losartan; Monopotassium Salt, Losartan; MK 954; DuP753; DuP 753; MK954; MK-954; Losartan Potassium; Losartan Monopotassium Salt; DuP-753; Cozaar; 2-Butyl-4-chloro-1-((2'-(1H-etrazol-5-yl) (1,1'-biDrugs* : LOSARTAN POTASSIUM; COZAAR
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-pentanoyl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)pyrrolidine-2-carboxamide  0   Losartan/*analogs & derivatives Ligands Receptor, Angiotensin, Type 1. ChemMedChem. 2007 Sep;2(9):1298-310.
HM70186  0   Losartan/*analogs & derivatives. Arch Pharm Res. 2009 Jul;32(7):1005-11
V8 compound  0   Losartan/*analogs & derivatives Receptor, Angiotensin, Type 1. J Pharm Biomed Anal 2006 Mar 18;40(5):1097-104
hydrochlorothiazide, losartan drug combination  0   *Hydrochlorothiazide *Losartan Drug Combinations. Hypertension 2005 Apr;45(4):513-21LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE; HYZAAR
2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-carboxaldehyde  140868-18-4   Losartan/*analogs & derivatives. Hypertension 1992 Mar;19(3):255-62

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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