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Hydroxymethyl and Formyl Transferases

More information in Books or onNLM PubMed
Definition: Enzymes that catalyze the transfer of hydroxymethyl or formyl groups. EC 2.1.2.     
Examples Aminomethyltransferase; Glutamate Formimidoyltransferase; Glycine Hydroxymethyltransferase; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase 		Other names Transferases, Hydroxymethyl; Transferases, Formyl; Transhydroxymethylases; Transformylases; Transformylase; Hydroxymethyltransferases; Hydroxymethyl Transferases; Formyltransferases; Formyl Transferases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FONG protein, human  EC 2.1.2.-   *Hydroxymethyl and Formyl Transferases. PLoS One 2011;6(5):e19641
Arakawa syndrome 1  0   *Metabolism, Inborn Errors *Hyperhomocysteinemia Hydroxymethyl and Formyl Transferases/deficiency.
DIT1 protein, S cerevisiae  EC 2.1.2.   *Hydroxymethyl and Formyl Transferases *Saccharomyces cerevisiae Proteins. Mol Cell Biol 2005 Aug;25(15):6772-88
purT protein, E coli  EC 2.1.2.-   *Hydroxymethyl and Formyl Transferases *Escherichia coli Proteins.
inosine monophosphate synthase  0   *Multienzyme Complexes *Nucleotide Deaminases *Hydroxymethyl and Formyl Transferases. Adv Exp Med Biol 1998;431:221-6
10-formyl-5,8-10-trideazafolic acid  143436-91-3   *Glutamates *Quinazolines Hydroxymethyl and Formyl Transferases/antagonists & inhibitors. Bioorg Med Chem 1997 Sep;5(9):1817-30
deoxycytidylate hydroxymethyltransferase  EC 2.1.2.8   *Hydroxymethyl and Formyl Transferases.
formylmethanofuran-tetrahydromethanopterin formyltransferase  EC 2.1.2.-   *Hydroxymethyl and Formyl Transferases. J Biol Chem 1986;261(35):16653
dUMP-hydroxymethylase  EC 2.1.2.-   *Hydroxymethyl and Formyl Transferases. J Virol 13(4):828;1974
methionyl-tRNA formyltransferase  EC 2.1.2.9   *Hydroxymethyl and Formyl Transferases. Biochim Biophys Acta 477:356;1977
3-methyl-2-oxobutanoate hydroxymethyltransferase  EC 2.1.2.11 5,10-methylenetetrahydrofolate alpha-ketoisovalerate hydroxymethyltransferase  *Hydroxymethyl and Formyl Transferases Bacterial Proteins. J Biol Chem 251(12):3780;1976; Methods Enzymol 62:204;1979
6-hydroxymethylbenzo(alpha)pyrene synthetase  EC 2.1.2.-   *Hydroxymethyl and Formyl Transferases. Arch Biochem Biophys 186(2):401;1978; Cancer Res 35(12):3731;1975; Carcinogenesis I W1 CA7624:p171;1976
deoxyhydroxymethylcytosine hydroxymethylase  EC 2.1.2.-   *Hydroxymethyl and Formyl Transferases. Genetics 86(3):501;1977
benzopyrene hydroxymethylase  EC 2.1.2.-   *Hydroxymethyl and Formyl Transferases. Arch Biochem Biophys 163(1):46;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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