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Choline-Phosphate Cytidylyltransferase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes the transfer of cytidylate (CMP) to choline phosphate to form CDPcholine. It is the rate-limiting enzyme in the choline pathway for the biosynthesis of phosphatidylcholine. Its activity is increased by glucocorticoids. EC 2.7.7.15.  DF: CDP CHOLINE SYNTHETASE    Other names Phosphocholine Cytidylyl-Transferase, CTP; Cytidylyltransferase, Choline-Phosphate; Cytidylyltransferase, CTP Phosphocholine; Cytidylyl-Transferase, CTP Phosphocholine; Cytidyltransferase, Phosphocholine; Cytidyltransferase, CTP Phosphorylcholine; Cytidyl Transferase, Phosphorylcholine; Choline Phosphate Cytidylyltransferase; CTP Phosphocholine Cytidylyl Transferase; CDP Choline Synthetase; Phosphorylcholine Cytidyl Transferase; Phosphocholine Cytidyltransferase; CTP Phosphorylcholine Cytidyltransferase; CTP Phosphocholine Cytidylyl-Transferase; CDP-Choline Synthetase; Transferase, Phosphorylcholine Cytidyl; Synthetase, CDP-Choline; Phosphorylcholine Cytidyltransferase, CTP; Phosphocholine Cytidylyltransferase, CTP; CTP Phosphocholine Cytidylyltransferase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CTP phosphocholine cytidylyltransferase, alpha isoform, human  EC 2.7.7.15   *Choline-Phosphate Cytidylyltransferase. Biochim Biophys Acta. 2011 Jun;1811(6):377-85
PCYT1B protein, human  EC 2.7.7.15   *Choline-Phosphate Cytidylyltransferase Isoenzymes. Clin Chim Acta. 2009 Oct;408(1-2):34-8
PCYT1A protein, human  EC 2.7.7.15   *Choline-Phosphate Cytidylyltransferase. BMC Med 2006;4:36
Pcyt1a protein, mouse  EC 2.7.7.15   *Choline-Phosphate Cytidylyltransferase. Mol Cell Biol 2005 Apr;25(8):3357-63
Cct1protein, Drosophila  EC 2.7.7.15   *Choline-Phosphate Cytidylyltransferase *Drosophila Proteins. Development. 2003 Dec;130(24):6075-87
CTP phosphocholine cytidylyltransferase, alpha isoform, rat  EC 2.7.7.15   *Choline-Phosphate Cytidylyltransferase. Biochemistry. 2003 Oct 14;42(40):11768-76
CTP phosphocholine cytidylyltransferase, beta isoform, mouse  EC 2.7.7.15   *Choline-Phosphate Cytidylyltransferase Protein Isoforms. Biochim Biophys Acta 2003 Jul 4;1633(1):1-12
CCT2 protein, Arabidopsis  EC 2.7.7.15   *Choline-Phosphate Cytidylyltransferase *Arabidopsis Proteins. Plant Cell Physiol 2002 Nov;43(11):1342-50
CCT1 protein, Arabidopsis  EC 2.7.7.15   *Choline-Phosphate Cytidylyltransferase *Arabidopsis Proteins. Plant Cell Physiol 2002 Nov;43(11):1342-50

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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