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ψ
ψ
Isoenzymes
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Definition
: Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.
IM general only; coordinate NIM with specific enzyme (IM)
Other names
Isozymes; Allozymes; Alloenzymes
Substance
CAS Registry & name
Categories
Source
Drugs
*
PCYT1B protein, human
EC 2.7.7.15
*Choline-Phosphate Cytidylyltransferase
Isoenzymes.
Clin Chim Acta. 2009 Oct;408(1-2):34-8
3 beta-
hydroxysteroid dehydrogenase type II
EC 1.1.1.145
*Progesterone Reductase
Isoenzymes.
GPAT4 protein, mouse
EC 2.3.1.15
*Glycerol-3-Phosphate O-Acyltransferase
Isoenzymes.
J Lipid Res. 2008 Apr;49(4); 823-31
Atp2b2 protein, mouse
EC 3.6.3.8
*Plasma Membrane Calcium-Transporting ATPases
Isoenzymes.
Capn3 protein, rat
EC 3.4.22.-
*Calpain
*Isoenzymes
*Muscle Proteins.
Mat1a protein, mouse
EC 2.5.1.6
*Methionine Adenosyltransferase
Isoenzymes.
FASEB J 2004 May;18(7):914-6
Prkcq protein, mouse
EC 2.7.1.-
*Isoenzymes
*Protein Kinase C
Zinc Fingers.
Pkcq protein, rat
EC 2.7.1.-
*Isoenzymes
*Protein Kinase C
Zinc Fingers.
adenosine deaminase-
complexing protein, Oryctolagus cuniculus
EC 3.4.14.5
*Adenosine Deaminase
*Glycoproteins
Isoenzymes.
ATP1A4 protein, human
EC 3.6.1.-
*Sodium-Potassium-Exchanging ATPase
Isoenzymes.
CYP4Z1 protein, human
EC 1.14.14.-
*Cytochrome P-450 Enzyme System
Breast Neoplasms
Isoenzymes.
Cancer Res. 2004 Apr 1;64(7):2357-64
agalsidase beta
EC 3.2.1.-
*alpha-Galactosidase
*Isoenzymes.
J Biotechnol 2002 May 23;95(3):280-2
FABRAZYME
SGMS1 protein, human
EC 2.7.8.-
*Membrane Proteins
*Nerve Tissue Proteins
*Transferases (Other Substituted Phosphate Groups)
Isoenzymes.
Biomol Eng 2002 Feb;18(6):263-8; Mol Biol (Mosk). 2003 Mar-Apr;37(2):315-24
topoisomerase III beta
EC 3.1.-
*DNA Topoisomerases, Type I
*Isoenzymes.
Biochem Biophys Res Commun 2001 Sep 14;287(1):282-7
peptidyl-
prolyl cis-
trans isomerase b
EC 5.2.1.-
*Peptidylprolyl Isomerase
Isoenzymes.
J Biomol NMR 2000 Sep;18(1):75-6
glutathione transferase M3-
3
EC 2.5.1.18
*Glutathione Transferase
Isoenzymes.
Neurochem Res 2000 May;25(5):733-6
agalsidase alfa
EC 3.2.1.-
*alpha-Galactosidase
Isoenzymes
Fabry Disease.
Clin Pharmacol Ther 2000 Oct;68(4):456
Akp3 protein, rat
EC 3.1.3.-
*Alkaline Phosphatase
*Isoenzymes.
Physiol Genomics 2000 Jun 29;3(1):1-8
Alpi protein, rat
EC 3.1.3.-
*Alkaline Phosphatase
*Isoenzymes.
Physiol Genomics 2000 Jun 29;3(1):1-8
lactate dehydrogenase 4
EC 1.1.1.27
*L-Lactate Dehydrogenase
Isoenzymes.
lactate dehydrogenase 3
EC 1.1.1.27
Isoenzymes
*L-Lactate Dehydrogenase.
lactate dehydrogenase 2
EC 1.1.1.27
*L-Lactate Dehydrogenase
Isoenzymes.
lactate dehydrogenase-
K
EC 1.1.1.27
*L-Lactate Dehydrogenase
Isoenzymes.
lactate dehydrogenase C4
EC 1.1.1.27.-
*L-Lactate Dehydrogenase
Isoenzymes.
lactate dehydrogenase 5
EC 1.1.1.27.-
*L-Lactate Dehydrogenase
Isoenzymes.
lactate dehydrogenase 1
EC 1.1.1.27.-
*L-Lactate Dehydrogenase
Isoenzymes.
Apl II protein kinase C
EC 2.7.1.-
*Isoenzymes
*Protein Kinase C.
Learn Mem 1997 Jan-Feb;3(5):389-401
glutathione S-
transferase alpha
EC 2.5.1.18
*Glutathione Transferase
*Isoenzymes.
Jpn J Cancer Res 1999 May;90(5):530-5
8-
methoxymethyl-
3-
isobutyl-
1-
methylxanthine
0
*Xanthines
Isoenzymes/antagonists & inhibitors.
Life Sci 1999;64(23):2081-8
NBR-
B isoenzyme
EC 2.7.4.-
*Isoenzymes
*Nucleoside-Diphosphate Kinase.
FEBS Lett 1999 Apr16;449(1):83-7
NBR-
A isoenzyme
EC 2.7.4.-
*Isoenzymes
*Nucleoside-Diphosphate Kinase.
FEBS Lett 1999 Apr 16;449(1):83-7
cytochrome P-
450 CYP2A14 (hamster)
0
*Cytochrome P-450 Enzyme System
Isoenzymes.
Arch Biochem Biophys 1998 Nov 15;359(2):241-8
phorbol 12-
pyrenebutyrate 13-
(3,3,3-
trifloro-
2-
diazopropioate)
0
*Diazonium Compounds
*Phorbols
Isoenzymes
Protein Kinase C.
Bioorg Med Chem 1998 Jul;6(7):1117-26
AMY1.2 protein, Hordeum vulgare
EC 3.2.1.1
*alpha-Amylases
*Isoenzymes
*Plant Proteins.
Structure 1998 May 15;6(5):649-59
SOD-
4 protein, C elegans
EC 1.15.1.-
*Isoenzymes
*Superoxide Dismutase
*Caenorhabditis elegans Proteins.
DNA Res 1998 Feb 28;5(1):25-30
protein tyrosine kinase Pyk2-
H
EC 2.7.1.-
*Isoenzymes
*Protein-Tyrosine Kinases.
J Biol Chem 1998 Jun 5;273(23):14301-8
glutathione S-
transferase 9.5-
2
EC 2.5.1.-
*Glutathione Transferase
*Isoenzymes.
Arch Biochem Biophys 1998 May 15;353(2):337-48
glutathione S-
transferase 9.5-
1
EC 2.5.1.-
*Glutathione Transferase
*Isoenzymes.
Arch Biochem Biophys 1998 May 15;353(2):337-48
smooth muscle short-
chain alcohol dehydrogenase
EC 1.1.-
*Alcohol Oxidoreductases
*Isoenzymes.
J Steroid Biochem Mol Biol 1997 Sep-Oct;63(1-3):115-21
ubiquitin C-
terminal hydrolase 8
EC 3.1.2.-
*Isoenzymes
*Thiolester Hydrolases.
Biochem J 1997 Jul 15;325( Pt 2):325-30
aldehyde dehydrogenase 1
EC 1.2.1.-
*Isoenzymes
*Retinal Dehydrogenase.
Adv Exp Med Biol 1997;414:19-27
glycogen phosphorylase 2 protein, Dictyostelium discoideum
EC 2.4.1.-
*Phosphorylases
DNA-Binding Proteins
Isoenzymes.
Biochim Biophys Acta 1997 Mar 20;1351(1-2):111-25; Dev Genet. 1993;14(4):313-22; J Biol Chem. 1992 Feb 5;267(4):2294-302
heme oxygenase-
2
EC 1.14.99.3
*Heme Oxygenase (Decyclizing)
Isoenzymes.
Biochim Biophys Acta 1997 Mar 20;1351(1-2):89-104
phosphoglycerate kinase, testis specific
EC 2.7.2.3
*Isoenzymes
*Phosphoglycerate Kinase.
Dev Genet 1996;19(4):321-32
amadoriase
EC 1.5.3.-
*Amino Acid Oxidoreductases
Isoenzymes.
J Biol Chem 1996 Dec 20;271(51):32803-9
tartrate-
resistant acid phosphatase
EC 3.1.3.-
*Acid Phosphatase
*Isoenzymes
Tumor Markers, Biological
Biological Markers.
Blood 1995 May 15;85(10):2839-44
AT-
II acetyltransferase
EC 2.3.1.-
*Arylamine N-Acetyltransferase
*Isoenzymes.
Pharmacogenetics 1994 Apr;4(2):91-100
AT-
I acetyltransferase
EC 2.3.1.-
*Arylamine N-Acetyltransferase
*Isoenzymes.
Pharmacogenetics 1994 Apr;4(2):91-100
N-
acetyltransferase 1
EC 2.3.1.5
*Arylamine N-Acetyltransferase
*Isoenzymes.
Pharmacogenetics 1994 Apr;4(2):82-90
basiliscusfibrase
EC 3.4.24.-
*Metalloendopeptidases
Crotalid Venoms
Isoenzymes.
Thromb Res 1994 May 15;74(4):355-67
CA9 protein, human
EC 4.2.1.1
*Antigens, Neoplasm
*Carbonic Anhydrases
Antigens, Neoplasm
Isoenzymes
Tumor Markers, Biological.
Am J Pathol 1994 Sep;145(3):598-609
protein kinase C beta
EC 2.7.1.-
*Protein Kinase C
Isoenzymes.
J Biol Chem 1994 Jul 29;269(30):19578-84
DNA topoisomerase II alpha
EC 5.99.1.3
*Antigens, Neoplasm
*DNA Topoisomerases, Type II
*DNA-Binding Proteins
Isoenzymes.
Neurosci Res 1994 Feb;19(1):51-7
protein kinase C gamma
EC 2.7.1.-
*Protein Kinase C
Isoenzymes.
Neuroreport 1994 Jan 12;5(4):381-4
protein kinase C lambda
EC 2.7.1.37
*Isoenzymes
*Protein Kinase C
Zebrafish Proteins.
J Biol Chem 1994 Apr 29;269(17):12677-83
proteinase D
EC 3.4.21.-
*Isoenzymes
*Kallikreins.
Endocrinology 1993 Sep;133(3):1051-60
proteinase P
EC 3.4.21.-
*Isoenzymes
*Kallikreins.
Endocrinology 1993 Sep;133(3):1051-60
protein kinase C eta
EC 2.7.1.-
*Protein Kinase C
Isoenzymes.
Tohoku J Exp Ther 1992 Oct;168(2):211-22
PCSK6 protein, human
EC 3.4.21.-
*Serine Endopeptidases
*Proprotein Convertases
Isoenzymes.
J Biochem (Tokyo) 1993 Feb;113(2):132-5
beta-
ketoacyl-
acyl carrier protein synthase I
EC 2.3.1.-
*Isoenzymes
*3-Oxoacyl-(Acyl-Carrier-Protein) Synthase.
J Biol Chem 1992 Nov 25;267(33):23999-4006
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