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Superoxide Dismutase

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Definition: An oxidoreductase that catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide. EC 1.15.1.1.     
Pharmacological Action Free Radical Scavengers 		Other names Hemocuprein; Cu-Zn Superoxide Dismutase; Superoxide Dismutase, Manganese; Superoxide Dismutase, Iron; Superoxide Dismutase, Cuprozinc; Superoxide Dismutase, Fe-Zn; Superoxide Dismutase, Cu-Zn; Superoxide Dismutase, Cobalt; Superoxide Dismutase, Ag-Zn; Mn Superoxide Dismutase; Mn SOD; Fe Zn Superoxide Dismutase; Fe Superoxide Dismutase; Dismutase, Superoxide; Dismutase, Mn-Superoxide; Dismutase, Manganese Superoxide; Dismutase, Iron Superoxide; Dismutase, Fe-Zn Superoxide; Dismutase, Fe-Superoxide; Dismutase, Cuprozinc Superoxide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-((3,5-dichlorophenoxy)methyl)-1H-pyrazol-3(2H)-one  0   *Pyrazoles Superoxide Dismutase/antagonists & inhibitors. J Med Chem. 2012 Jan 12;55(1):515-27.
Extramel  EC 1.15.1.1.   *Plant Extracts *Superoxide Dismutase. Nutr J. 2009;8() (dup#19):40
Sod-3 protein, C elegans  EC 1.15.1.1   *Superoxide Dismutase *Caenorhabditis elegans Proteins. J Biol Chem 1997 Nov 7;272(45):28652-9
Vitix  0   *Catalase *Superoxide Dismutase. Int J Dermatol 2005 Nov;44(11):969-70
Sod3 protein, mouse  EC 1.15.1.1   *Superoxide Dismutase.
Sod3 protein, rat  EC 1.15.1.1   *Superoxide Dismutase.
SOD1 G37R protein, mouse  EC 1.15.1.1   *Superoxide Dismutase. J Neurochem 2003 Jan 1;84(1):77-86
SOD3 protein, human  EC 1.15.1.1   *Superoxide Dismutase. J Biol Chem 2001 Nov 23;276(47):43784-91
lecithinized superoxide dismutase  EC 1.15.1.-   *Phosphatidylcholines *Superoxide Dismutase. Biochem Biophys Res Commun 2001 Aug 3;285(5):1220-5
superoxide dismutase 2  EC 1.15.1.1   *Superoxide Dismutase. J Neurochem 2001 Jul;78(1):32-41
Hev b 10  0   *Plant Proteins *Superoxide Dismutase Allergens Latex Hevea. Allergy 2001 Jan;56(1):85-6
nlr protein, Desulfovibrio gigas  EC 1.15.1.1   *Bacterial Proteins *Superoxide Dismutase *Iron-Binding Proteins. J Biol Chem 2000 Sep 15;275(37):28439-48
SC 68328  0   *Organometallic Compounds Manganese Superoxide Dismutase. J Mass Spectrom 2000 Mar;35(3):354-60
sodC protein, E coli  0   *Superoxide Dismutase *Escherichia coli Proteins. FEBS Lett 1998 Nov 13;439(1-2):192-6
Asp f 6 allergen  0   *Superoxide Dismutase *Antigens, Plant Fungal Proteins. Int Immunol 1998 Aug;10(8):1211-6
SOD-4 protein, C elegans  EC 1.15.1.-   *Isoenzymes *Superoxide Dismutase *Caenorhabditis elegans Proteins. DNA Res 1998 Feb 28;5(1):25-30
superoxide dismutase 1  EC 1.15.1.-   *Superoxide Dismutase Amyotrophic Lateral Sclerosis. Biochem Biophys Res Commun 1997 Dec 18;241(2):251-7
SOD1 G93A protein  EC 1.15.1.-   *Superoxide Dismutase Amyotrophic Lateral Sclerosis. J Cell Biol 1997 Dec 1;139(5):1307-15
LYS7 protein, S cerevisiae  EC 1.15.1.1   *Superoxide Dismutase *Molecular Chaperones *Saccharomyces cerevisiae Proteins. Gene 1995 Aug 30;162(1):87-92
SodA protein, Bacteria  0   *Bacterial Proteins *Superoxide Dismutase. J Bacteriol 1995 Sep;177(18):5254-60
SodA3 protein, Plectonema boryanum  EC 1.15.1.1   *Bacterial Proteins *Superoxide Dismutase. J Bacteriol 1995 Feb;177(4):964-72
SodA2 protein, Plectonema boryanum  EC 1.15.1.1   *Bacterial Proteins *Superoxide Dismutase. J Bacteriol 1995 Feb;177(4):964-72
SodA1 protein, Plectonema boryanum  EC 1.15.1.1   *Bacterial Proteins *Superoxide Dismutase. J Bacteriol 1995 Feb;177(4):964-72
SodB protein, Bacteria  0   *Bacterial Proteins *Superoxide Dismutase Escherichia coli Proteins. Gene 1994 May 27;143(1):111-6
polyhemoglobin-superoxide dismutase-catalase  0   *Catalase *Hemoglobins *Superoxide Dismutase Blood Substitutes. Chem Phys Lipids 1993 Nov;66(1-2):609-21
monomethoxypolyethylene glycol-superoxide dismutase  0   *Polyethylene Glycols *Superoxide Dismutase. Agents Actions 1992;Spec No:C112-4
polyoxyethylene-superoxide dismutase  0   *Polyethylene Glycols *Superoxide Dismutase. Jpn J Cancer Res 1992 Aug;83(8):899-906
superoxide dismutase-poly(styrene co-maleic acid butyl ester)  0   *Polystyrenes *Superoxide Dismutase. Biochim Biophys Acta 1991;1073(2):374
polyethylene glycol-superoxide dismutase  0   *Polyethylene Glycols *Superoxide Dismutase.
Pharma Action Free Radical Scavengers 		Am J Physiol 1990;253(3 PT 1):C429
rubrerythrins  0   *Hemerythrin *Rubredoxins Peroxidases Superoxide Dismutase. Biochemistry 1988;25(5):1636; J Bacteriol 1996 Dec;178(24):7152-8
epurox  0   *Catalase *Superoxide Dismutase Drug Combinations. Arch Roum Pathol Exp Microbiol 1986;45(1):75
bacteriocuprein  0   *Superoxide Dismutase. J Biol Chem 1981;256(12):6080
orgotein  9016-01-7   *Metalloproteins Superoxide Dismutase.
Pharma Action Anti-Inflammatory Agents, Non-Steroidal 		Acta Radiol Oncol Radiat Phys Biol 1979;18(4):305; Ann Neurol 5(2):107;1979; Arzneim Forsch 1979;29(5):781; Curr Ther Res 18(3):466;1975; Curr Ther Res 19(2):198;1976; Curr Ther Res 20(1):62;1976; Equine Vet J 10(2):122;1978; Eur Urol 3:216;1977; Int Urol Nephrol 6(2):61;1974; J Am Vet Med Assoc 174(3):261;1979; J Am Vet Med Assoc 1979;175(3):248; J Dent Res 1979;58(9):1910; J Rheumatol 1980;7(1):24; J S Afr Vet Assoc 47(1):39;1976; Lancet II(8080):95;1978; Mod Vet Pract 54(7):17;1973; Mod Vet Pract 58(12):1009;1977; Toxicol Appl Pharmacol 26:184-202;1973; Vet Med Small Anim Clin 71(3):289;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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