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Retinal Dehydrogenase

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Definition: A metalloflavoprotein enzyme involved the metabolism of VITAMIN A, this enzyme catalyzes the oxidation of RETINAL to RETINOIC ACID, using both NAD+ and FAD coenzymes. It also acts on both the 11-trans- and 13-cis-forms of RETINAL.      Other names Retinal Dehydrogenase, Cytosolic; Dehydrogenase, Retinal; Dehydrogenase, Cytosolic Retinal; Cytosolic Retinal Dehydrogenase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RALDH4 protein, mouse  EC 1.2.1.36   *Retinal Dehydrogenase. Biochim Biophys Acta. 2009 Dec;1790(12):1660-4
ALDH1A2 protein, human  EC 1.2.1.36   *Retinal Dehydrogenase. BMC Med Genet. 2009;10() (dup#3):113
Raldh4 protein, zebrafish  EC 1.2.1.36   *Zebrafish Proteins *Retinal Dehydrogenase. Gene Expr Patterns 2008 Apr;8(4):248-53
Raldh3 protein, zebrafish  EC 1.2.1.36   *Zebrafish Proteins *Retinal Dehydrogenase Eye Proteins. Gene Expr Patterns 2008 Apr;8(4):248-53
RALDH3 protein, rat  EC 1.2.1.36   *Retinal Dehydrogenase. Cell Tissue Res 2007 Apr;328(1):129-35
RALDH1 protein, rat  EC 1.2.1.36   *Retinal Dehydrogenase. Gene 1997 Jun 3;191(2):167-72
RALDH2 protein, rat  EC 1.2.1.36   *Retinal Dehydrogenase. Pediatr Surg Int. 2007 May;23(5):391-6
Raldh2 protein, zebrafish  EC 1.2.1.36   *Zebrafish Proteins *Retinal Dehydrogenase. Development 2001 Aug;128(16):3081-94
Rdh12 protein, mouse  EC 1.2.1.36   *Retinal Dehydrogenase. Mol Cell Biol 2007 Feb;27(4):1370-9
retinaldehyde dehydrogenase 3, mouse  EC 1.2.1.36   *Retinal Dehydrogenase. Mech Dev 2000 Jul;95(1-2):283-9
aldehyde dehydrogenase 1  EC 1.2.1.-   *Isoenzymes *Retinal Dehydrogenase. Adv Exp Med Biol 1997;414:19-27

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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