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Arylamine N-Acetyltransferase

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Definition: An enzyme that catalyzes the transfer of acetyl groups from ACETYL-COA to arylamines. It can also catalyze acetyl transfer between arylamines without COENZYME A and has a wide specificity for aromatic amines, including SEROTONIN. However, arylamine N-acetyltransferase should not be confused with the enzyme ARYLALKYLAMINE N-ACETYLTRANSFERASE which is also referred to as SEROTONIN ACETYLTRANSFERASE.  do not confuse with ARYLALKYLAMINE N-ACETYLTRANSFERASE    Other names Arylamine Acetyltransferases; Arylamine Acetylases; N-Acetyltransferase, Arylamine; N-Acetyltransferase, Acetyl-CoA Arylamine; Arylamine N-Acetyltransferase, Acetyl-CoA; Arylamine N Acetyltransferase; Acetyltransferases, Arylamine; Acetylases, Arylamine; Acetylase, Arylamine; Acetyl CoA Arylamine N Acetyltransferase; Arylamine Acetylase; Acetyl-CoA Arylamine N-Acetyltransferase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NAT2 protein, rat  EC 2.3.1.5   *Arylamine N-Acetyltransferase. Drug Metab Dispos 2008 Dec;36(12):2452-9
N acetyltransferase deficiency  0   *Metabolism, Inborn Errors Arylamine N-Acetyltransferase/deficiency.
Nat2 enzyme, mouse  EC 2.3.1.5   *Arylamine N-Acetyltransferase. Cytogenet Cell Genet 2000;90(1-2):134-8
NAT2 protein, human  EC 2.3.1.5   *Arylamine N-Acetyltransferase.
ARD1 protein, Trypanosoma brucei  EC 2.3.1.-   *Arylamine N-Acetyltransferase *Protozoan Proteins. Mol Biochem Parasitol 2000 Dec;111(2):309-17
AT-II acetyltransferase  EC 2.3.1.-   *Arylamine N-Acetyltransferase *Isoenzymes. Pharmacogenetics 1994 Apr;4(2):91-100
AT-I acetyltransferase  EC 2.3.1.-   *Arylamine N-Acetyltransferase *Isoenzymes. Pharmacogenetics 1994 Apr;4(2):91-100
N-acetyltransferase 1  EC 2.3.1.5   *Arylamine N-Acetyltransferase *Isoenzymes. Pharmacogenetics 1994 Apr;4(2):82-90
MAK3 protein, S cerevisiae  EC 2.3.1.88   *Arylamine N-Acetyltransferase *Saccharomyces cerevisiae Proteins. J Biol Chem 1992 Oct 5;267(28):20270-6
norcantharidin  5442-12-6   *Bicyclo Compounds, Heterocyclic Arylamine N-Acetyltransferase/antagonists & inhibitors. J Pharm Biomed Anal 1989;7(12):1635
bromoacetanilide  103373-69-9   *Acetanilides Arylamine N-Acetyltransferase/antagonists & inhibitors. J Biol Chem 1988;263(16):7521
isoniazid acetyltransferase  EC 2.3.1.-   *Arylamine N-Acetyltransferase. Eur J Respir Dis 1985;67(1):17

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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