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GTP Phosphohydrolases

More information in Books or onNLM PubMed
Definition: Enzymes that hydrolyze GTP to GDP. EC 3.6.1.-.  GTP PHOSPHOHYDROLASE ACTIVATORS is available   
Examples Dynamins; GTP-Binding Proteins
Other names Triphosphate Phosphohydrolases, Guanosine; Phosphohydrolases, Guanosine Triphosphate; Phosphohydrolases, GTP; Phosphohydrolase, GTP; GTP Phosphohydrolase; Guanosinetriphosphatases; Guanosine Triphosphate Phosphohydrolases; GTPases; GTPase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Parcs protein, human  EC 3.6.1.-.   *GTP Phosphohydrolases. Biochim Biophys Acta. 2011 Oct;1813(10):1708-16
NOA1 protein, mouse  EC 3.6.1.-.   *GTP Phosphohydrolases. Mol Biol Cell. 2011 Jan 1;22(1):1-11
Rbg2 protein, S cerevisiae  EC 3.6.1.-   *GTP Phosphohydrolases *Saccharomyces cerevisiae Proteins. Nucleic Acids Res 2011 Mar;39(6):2221-33
Rem2 protein, zebrafish  EC 3.6.1.-   *GTP Phosphohydrolases *Zebrafish Proteins. Cell Cycle 2010 Sep;9(17):3414-22
GIMAP2 protein, human  EC 3.6.1.-   *Membrane Proteins *GTP Phosphohydrolases. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jun 1;66(Pt 6):725-9
Arl8 protein, C elegans  EC 3.6.1.-   *GTP Phosphohydrolases *Caenorhabditis elegans Proteins. Mol Biol Cell 2010 Jul 15;21(14):2434-42
SLIP-GC protein, human  EC 3.6.1.-   *Nuclear Proteins *GTP Phosphohydrolases. J Biol Chem 2009 Oct 30;284(44):30652-61
EAT-3 protein, C elegans  EC 3.6.1.-   *GTP Phosphohydrolases *Caenorhabditis elegans Proteins Mitochondrial Proteins. J Cell Biol 2009 Aug 24;186(4):525-40
FZO-1 protein, C elegans  EC 3.6.1.-   *GTP Phosphohydrolases *Caenorhabditis elegans Proteins Mitochondrial Proteins. J Cell Biol 2009 Aug 24;186(4):525-40
atlastin protein, Drosophila  EC 3.6.1.-   *GTP Phosphohydrolases *Drosophila Proteins. Nature. 2009 Aug 20;460(7258):978-83
Rab13 protein, rat  EC 3.6.1.-   *GTP Phosphohydrolases Tight Junctions. Biol Reprod 2009 Mar;80(3):590-601
NOA1 protein, human  EC 3.6.1.-.   *GTP Phosphohydrolases. J Biol Chem 2009 Feb 20;284(8):5414-24
YfgD protein, E coli  EC 3.6.1.-   *GTP Phosphohydrolases *Escherichia coli Proteins. Microbiol Res 2009;164(1):1-8
Gimap5 protein, mouse  EC 3.6.1.-   *GTP Phosphohydrolases. Blood 2008 Dec 15;112(13):4905-14
CRAG protein, mouse  EC 3.6.1.-   *GTP Phosphohydrolases. EMBO Rep 2008 Apr;9(4):393-9
EMB2473 protein, Arabidopsis  EC 3.6.1.-   *GTP Phosphohydrolases *Arabidopsis Proteins. Plant Cell 2008 Mar;20(3):589-601
Guf1 protein, S cerevisiae  EC 3.6.1.-.   *GTP Phosphohydrolases *Saccharomyces cerevisiae Proteins Cell Membrane. J Biol Chem 2008 Jun 20;283(25):17139-46
ATL3 protein, human  EC 3.6.5.-   *GTP Phosphohydrolases. Hum Mol Genet 2008 Jun 1;17(11):1591-604
atlastin-2 protein, human  EC 3.6.1.-   *GTP Phosphohydrolases. Hum Mol Genet 2008 Jun 1;17(11):1591-604
PIKE protein, mouse  EC 3.6.1.-   *Nerve Tissue Proteins *GTP Phosphohydrolases. Nat Cell Biol 2008 Jun;10(6):698-706
RERG protein, human  EC 3.6.1.-.   *GTP Phosphohydrolases Genes, Tumor Suppressor. Methods Enzymol 2006;407():(513-27
dead end protein, Drosophila  EC 3.6.1.-   *GTP Phosphohydrolases *Drosophila Proteins. Dev Biol 2007 Nov 15;311(2):487-99
Nog1 protein, mouse  EC 3.6.1.-   *GTP Phosphohydrolases. Mol Cell Biol 2007 Nov;27(21):7735-44
Iigp2 protein, mouse  EC 3.6.1.-   *GTP Phosphohydrolases. J Immunol 2007 Aug 1;179(3):1814-24
Efl1 protein, S cerevisiae  EC 3.6.1.-   *GTP Phosphohydrolases *Saccharomyces cerevisiae Proteins. Nat Genet 2007 Apr;39(4):486-95
RAN3 protein, Arabidopsis  0   *Cell Cycle Proteins *Arabidopsis Proteins GTP Phosphohydrolases. Ann Bot (Lond) 2006 Dec;98(6):1179-87
SIN2 protein, Arabidopsis  EC 3.6.1.-   *GTP Phosphohydrolases *Arabidopsis Proteins Mitochondrial Proteins. Genetics 2006 Oct;174(2):707-18
Irgb10 protein, mouse  EC 3.6.1.-.   *GTP Phosphohydrolases. Proc Natl Acad Sci U S A 2006 Sep 19;103(38):14092-7
EDR3 protein, Arabidopsis  EC 3.6.5.5   *GTP Phosphohydrolases *Arabidopsis Proteins Microtubule-Associated Proteins. Plant J 2006 Jul;47(1):75-84
CDC10 protein, S cerevisiae  EC 3.6.1.-   *Membrane Proteins *GTP Phosphohydrolases *Saccharomyces cerevisiae Proteins.
ARL8A protein, human  EC 3.6.1.-   *GTP Phosphohydrolases. J Cell Sci 2006 Apr 15;119(Pt 8):1494-503
Spg1 protein, S pombe  EC 3.6.1.-   *GTP Phosphohydrolases *Schizosaccharomyces pombe Proteins. Genes Dev 1997 Jun 15;11(12):1519-34
Lsg1 protein, human  EC 3.6.1.-   *GTP Phosphohydrolases. BMC Biol 2005;3:21
Grn1 protein, S pombe  EC 3.6.1.-   *GTP Phosphohydrolases *Schizosaccharomyces pombe Proteins. Mol Biol Cell 2006 Jan;17(1):460-74
GIMAP8 protein, mouse  EC 3.6.1.-   *GTP Phosphohydrolases. J Cell Biochem 2005 Oct 1;96(2):339-48
TrmE protein, E coli  EC 3.6.1.-   *GTP Phosphohydrolases *Escherichia coli Proteins. Mol Microbiol 2004 Nov;54(4):948-61
Opa1 protein, rat  EC 3.6.1.-   *GTP Phosphohydrolases.
Opa1 protein (GTPase), mouse  EC 3.6.1.-   *GTP Phosphohydrolases.
MnmE protein, E coli  EC 3.6.1.-   *GTP Phosphohydrolases *Escherichia coli Proteins. J Biomol NMR 2004 Mar;28(3):307-8
Iigp1 protein, mouse  EC 3.6.1.-   *GTP Phosphohydrolases.
Rhog protein, rat  0   *GTP Phosphohydrolases.
Rhog protein, mouse  0   *GTP Phosphohydrolases Nerve Tissue Proteins.
Mfn2 protein, mouse  EC 3.6.1.-   *GTP Phosphohydrolases. Science 2004 Aug 6;305(5685):858-62
Mfn1 protein, mouse  EC 3.6.1.-   *GTP Phosphohydrolases. Science 2004 Aug 6;305(5685):858-62
Rhoj protein, mouse  EC 3.6.1.-   *GTP Phosphohydrolases.
RAB18 protein, human  0   *rab GTP-Binding Proteins GTP Phosphohydrolases.
YjiA protein, E coli  EC 3.6.1.-   *GTP Phosphohydrolases *Escherichia coli Proteins. Proteins 2004 Feb 1;54(2):371-4
Mtg1 protein, S cerevisiae  EC 3.6.1.-   *GTP Phosphohydrolases *Saccharomyces cerevisiae Proteins Mitochondrial Proteins. Mol Biol Cell 2003 Jun;14(6):2292-302
Gvin1 protein, mouse  EC 3.6.1.-   *Nuclear Proteins *GTP Phosphohydrolases. J Immunol. 2003 Aug 1;171(3):1255-65
GVINP1 protein, human  EC 3.6.1.-   *Nuclear Proteins *GTP Phosphohydrolases. J Immunol. 2003 Aug 1;171(3):1255-65
MFN2 protein, human  EC 3.6.1.-   *GTP Phosphohydrolases *Mitochondrial Proteins Membrane Proteins. DNA Res 1996 Oct 31;3(5):321-9, 341-54
Mfn1 protein, human  EC 3.6.5.-   *GTP Phosphohydrolases *Mitochondrial Membrane Transport Proteins. J Cell Sci 2002 Apr 15;115(Pt 8):1663-74
DIRAS1 protein, human  EC 3.6.1.-   *GTP Phosphohydrolases *Tumor Suppressor Proteins. J Biol Chem 2002 Oct 25;277(43):41070-8
YjeQ protein, E coli  EC 3.6.1.-   *GTP Phosphohydrolases *Escherichia coli Proteins. Biochemistry 2002 Sep 17;41(37):11109-17
Rab7 protein, Entamoeba histolytica  EC 3.6.1.-   *Protozoan Proteins *GTP Phosphohydrolases Biological Markers. Mol Biochem Parasitol 2002 May;121(2):254-64
dynamin, Anopheles gambiae  EC 3.6.1.-   *GTP Phosphohydrolases. Parasitol Res 2002 Jan;88(1):1-8
ADL2b protein, Arabidopsis  EC 3.6.1.-   *GTP Phosphohydrolases *Arabidopsis Proteins Mitochondrial Proteins. Proc Natl Acad Sci U S A 2002 Apr 16;99(8):5727-31
Mms16 protein, Magnetospirillum magneticum  EC 3.6.1.-   *Bacterial Proteins *GTP Phosphohydrolases. J Biol Chem 2001 Dec 21;276(51):48183-8
Nug1 protein, S cerevisiae  EC 3.6.1.-   *Saccharomyces cerevisiae Proteins *GTP Phosphohydrolases Nuclear Proteins. Mol Cell 2001 Sep;8(3):517-29
VpsA protein, Aspergillus nidulans  EC 3.6.1.-   *Fungal Proteins *GTP Phosphohydrolases. Gene 2001 May 2;268(1-2):23-30
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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