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Heterotrimeric GTP-Binding Proteins

More information in Books or onNLM PubMed
Definition: GTP-BINDING PROTEINS that contain three non-identical subunits. They are found associated with members of the seven transmembrane domain superfamily of G-PROTEIN-COUPLED RECEPTORS. Upon activation the GTP-BINDING PROTEIN ALPHA SUBUNIT of the complex dissociates leaving a dimer of a GTP-BINDING PROTEIN BETA SUBUNIT bound to a GTP-BINDING PROTEIN GAMMA SUBUNIT.  GEN or unspecified; prefer specifics; DF: HET G PROTEINS   
Examples GTP-Binding Protein alpha Subunits; Transducin 		Other names Heterotrimeric GTP Binding Proteins; Heterotrimeric G Proteins; GTP-Binding Proteins, Heterotrimeric; G-Proteins, Heterotrimeric; Heterotrimeric G-Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
XLG3 protein, Arabidopsis  EC 3.6.1.46   *Heterotrimeric GTP-Binding Proteins *Arabidopsis Proteins. Plant J 2008 Jan;53(2):248-63
XLG2 protein, Arabidopsis  EC 3.6.1.46   *Heterotrimeric GTP-Binding Proteins *Arabidopsis Proteins. Plant J 2008 Jan;53(2):248-63
alpha-gustducin, mouse  EC 3.6.1.46   *Heterotrimeric GTP-Binding Proteins Protein Subunits. Proc Natl Acad Sci U S A 2007 Sep 18;104(38):15069-74
Gnat2 protein, mouse  0   *Heterotrimeric GTP-Binding Proteins Eye Proteins Membrane Proteins. Invest Ophthalmol Vis Sci 2006 Nov;47(11):5017-21
Ggamma13 protein, mouse  0   *Heterotrimeric GTP-Binding Proteins Protein Subunits. Nat Neurosci 1999 Dec;2(12):1055-62
Gnb1 protein, mouse  0   *Heterotrimeric GTP-Binding Proteins.
Gnat1 protein, rat  0   *Heterotrimeric GTP-Binding Proteins Eye Proteins Membrane Proteins.
Galpha402 protein, Trichomonas vaginalis  0   *Heterotrimeric GTP-Binding Proteins. Mol Biochem Parasitol 2003 Jul;129(2):179-89
TTC1 protein, human  0   *Heterotrimeric GTP-Binding Proteins *Adaptor Proteins, Vesicular Transport. Mol Cell Biol. 2003 Jun;23(11):3847-58
G-protein beta3 subunit  0   *Heterotrimeric GTP-Binding Proteins Protein Subunits. Nat Genet 1998 Jan;18(1):45-8
KISS1R protein, human  0   *Receptors, G-Protein-Coupled Heterotrimeric GTP-Binding Proteins. FEBS Lett 1999 Mar 5;446(1):103-7
Bscl2 protein, mouse  0   *Heterotrimeric GTP-Binding Proteins. Genomics 1998 Oct 15;53(2):220-30
GPR35 protein, human  0   *Receptors, G-Protein-Coupled Heterotrimeric GTP-Binding Proteins. Genomics 1998 Jan 15;47(2):310-3
MCHR1 protein, human  0   *Receptors, Somatostatin Heterotrimeric GTP-Binding Proteins. FEBS Lett 1996 Dec 2;398(2-3):253-8
git5 protein, S pombe  0   *Heterotrimeric GTP-Binding Proteins *Schizosaccharomyces pombe Proteins. Genetics 2000 Apr;154(4):1463-71; Mol Gen Genet 1996 Aug 27;252(1-2):20-32
Mrgprf protein, rat  0   *Receptors, Cell Surface Heterotrimeric GTP-Binding Proteins. Proc Natl Acad Sci USA 1990;87(8):3052
GNAT1 protein, human  0   *Heterotrimeric GTP-Binding Proteins Eye Proteins Membrane Proteins. J Biol Chem 1982;257(11):6452

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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