encyclopedia of medical concepts
ψ 
ψ 

Antimicrobial Cationic Peptides

More information in Books or onNLM PubMed
Definition: Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.     
Pharmacological Action Anti-Infective Agents
See Also Blood Bactericidal Activity
Examples Cathelicidins; Cecropins; Defensins; Dermcidins; Histatins; Magainins; Melitten; Polymyxins; Thionins 		Other names Proteins, Microbicidal Cationic; Peptides, Cationic Antimicrobial; Peptides, Antimicrobial Cationic; Cationic Proteins, Microbicidal; Cationic Peptides, Antimicrobial; Amphipathic Cationic Antimicrobial Peptides; Antimicrobial Peptides, Cationic; Microbicidal Cationic Proteins; Cationic Antimicrobial Peptides
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
NK-18 peptide  0   *Antimicrobial Cationic Peptides. Biochimie. 2012 Jan;94(1):184-91.
tenecin 4 protein, Tenebrio molitor  0   *Insect Proteins *Antimicrobial Cationic Peptides. Dev Comp Immunol. 2012 Mar;36(3):540-6
PGLa-H peptide, Xenopus  0   *Antimicrobial Cationic Peptides *Xenopus Proteins Methicillin-Resistant Staphylococcus aureus/drug effects. Int J Antimicrob Agents. 2011 Dec;38(6):510-5
crustinPm7 protein, Penaeus monodon  0   *Antimicrobial Cationic Peptides. Dev Comp Immunol. 2012 Jan;36(1):208-15
crustinPm1 protein, Penaeus monodon  0   *Antimicrobial Cationic Peptides. Dev Comp Immunol. 2012 Jan;36(1):208-15
double WAP domain-containing protein, Eriocheir sinensis  0   *Antimicrobial Cationic Peptides Brachyura. Dev Comp Immunol. 2012 Jan;36(1):183-90
prolixicin, Rhodnius prolixus  0   *Antimicrobial Cationic Peptides. Insect Mol Biol. 2011 Dec;20(6):775-86
BPC194  0   *Peptides, Cyclic *Antimicrobial Cationic Peptides. Biochim Biophys Acta. 2011 Sep;1808(9):2197-205
LCI peptide, Bacillus subtilis  0   *Bacterial Proteins *Antimicrobial Cationic Peptides. Biochemistry 2011 May 10;50(18):3621-7
LFchimera peptide  0   *Antimicrobial Cationic Peptides. J Appl Microbiol 2010 Oct;109(4):1311-8
I-G-K-E-F-K-R-I-V-Q-R-I-K-D-F-L-R-N-L-V-P-R-T-E-S  0   *Antimicrobial Cationic Peptides. Chemistry. 2011 Feb 25;17(9):2656-65
pelteobagrin protein, Pelteobagrus fulvidraco  0   *Antimicrobial Cationic Peptides *Fish Proteins. Comp Biochem Physiol B Biochem Mol Biol 2011 Feb;158(2):149-54
SD-8 peptide  0   *Antimicrobial Cationic Peptides. Amino Acids 2010 Nov;39(5):1493-505
BPC96 peptide  0   *Peptides, Cyclic *Antimicrobial Cationic Peptides. Peptides 2010 Nov;31(11):2017-26
alyteserin 1c, Alytes obstetricans  0   *Antimicrobial Cationic Peptides. Peptides 2010 Oct;31(10):1806-10
innate defense regulating peptide 1018  0   *Antimicrobial Cationic Peptides. Chem Biol 2010 Sep 24;17(9):970-80
lysyl-lysyl-valyl-valyl-phenylalanyl-tryptophyl-valyl-lysyl-phenylalanyl-lysine  0   *Antimicrobial Cationic Peptides. Pharm Res 2007 Aug;24(8):1544-50
novicidin  0   *Antimicrobial Cationic Peptides. BMC Microbiol 2008 Nov 26;8:205
di-K19Hc peptide  0   *Antimicrobial Cationic Peptides. Antimicrob Agents Chemother 2003 Aug;47(8):2481-6
P5-18mer peptide  0   *Antimicrobial Cationic Peptides. Biochem Biophys Res Commun 2010 Sep 3;399(4):
penaeidin 5, Fenneropenaeus chinensis  0   *Antimicrobial Cationic Peptides. Dev Comp Immunol 2010 Aug;34(8):874-83
K9L8W peptide  0   *Antimicrobial Cationic Peptides. Peptides 2010 Jul;31(7):1251-61
LyeTx I protein, Lycosa erythrognatha  0   *Antimicrobial Cationic Peptides Spider Venoms. Amino Acids 2010 Jun;39(1):135-44
papiliocin protein, Papilio xuthus  0   *Antimicrobial Cationic Peptides. Mol Cells 2010 Apr;29(4):419-23
oncocin  0   *Antimicrobial Cationic Peptides. J Med Chem 2010 Jul 22;53(14):5240-7
hinnavin II, Artogeia rapae  0   *Antimicrobial Cationic Peptides. Mol Cells 1997 Aug 31;7(4):509-13
meucin-25, Mesobuthus eupeus  0   *Scorpion Venoms *Antimicrobial Cationic Peptides. Biochimie 2010 Apr;92(4):350-9
meucin-24, Mesobuthus eupeus  0   *Scorpion Venoms *Antimicrobial Cationic Peptides. Biochimie 2010 Apr;92(4):350-9
IDR 1002  0   *Antimicrobial Cationic Peptides. J Immunol 2010 Mar 1;184(5):2539-50
ponericin G1, Pachycondyla goeldii  0   *Antimicrobial Cationic Peptides. Biomaterials 2010 Mar;31(8):2348-57
osmin protein, Osmia rufa  0   *Bee Venoms *Antimicrobial Cationic Peptides. Toxicon 2010 Jan;55(1):20-7
RGLCYRPRFVCVG-NH(2)  0   *Antimicrobial Cationic Peptides. FEBS J. 2010 Feb;277(4):1010-22
RGLCYCRGRFCVCVG-NH(2)  0   *Antimicrobial Cationic Peptides. FEBS J. 2010 Feb;277(4):1010-22
k(9)a(10)-KLAL  0   *Antimicrobial Cationic Peptides. Chembiochem. 2009 Dec 14;10(18):2884-92
l(11)k(12)-KLAL  0   *Antimicrobial Cationic Peptides. Chembiochem. 2009 Dec 14;10(18):2884-92
KLAL peptide  0   *Antimicrobial Cationic Peptides. Chembiochem. 2009 Dec 14;10(18):2884-92
hepcidin 25, human  0   *Antimicrobial Cationic Peptides. BMC Cancer. 2009;9() (dup#72):270
lasioglossin III  0   *Antimicrobial Cationic Peptides. Chembiochem 2009 Aug 17;10(12):2089-99
lasioglossin II  0   *Antimicrobial Cationic Peptides. Chembiochem 2009 Aug 17;10(12):2089-99
lasioglossin I  0   *Antimicrobial Cationic Peptides. Chembiochem 2009 Aug 17;10(12):2089-99
lysyl-lysyl-lysyl-lysyl-prolyl-leucyl-phenylalanyl-glycyl-leucyl-phenylalanyl-phenylalanyl-glycyl-leucyl-phenylalanine  0   *Antimicrobial Cationic Peptides. Peptides 2009 Sep;30(9):1608-12
hyastatin, Hyas araneus  0   *Antimicrobial Cationic Peptides. Mol Immunol. 2009 Aug;46(13):2585-9604-12
leptoglycin, Leptodactylus pentadactylus  0   *Antimicrobial Cationic Peptides. Toxicon. 2009 Jul;54(1):23-32
microplusin protein, Boophilus microplus  0   *Antimicrobial Cationic Peptides. Dev Comp Immunol 2004 Mar;28(3):191-200
hepcidin (6-25), human  0   *Peptide Fragments *Antimicrobial Cationic Peptides. Tohoku J Exp Med 2009;218(2):93-8
antimicrobial peptide AG-30  0   *Antimicrobial Cationic Peptides. J Cell Mol Med. 2009 Mar;13(3):535-46
aurein 3.3 peptide  0   *Antimicrobial Cationic Peptides. Biochim Biophys Acta. 2009 Jul;1788(7):1482-96
melimine  0   *Antimicrobial Cationic Peptides. Biofouling 2009;25(6):517-24
papillosin protein, Halocynthia papillosa  0   *Antimicrobial Cationic Peptides. J Pept Sci 2009 Jan;15(1):48-55
halocyntin protein, Halocynthia papillosa  0   *Antimicrobial Cationic Peptides. J Pept Sci 2009 Jan;15(1):48-55
RP-1 peptide  0   *Antimicrobial Cationic Peptides. Biopolymers 2009 Jan;91(1):1-13
piscidin 4, striped bass  0   *Antimicrobial Cationic Peptides. Comp Biochem Physiol B Biochem Mol Biol 2009 Apr;152(4):299-305
acetyl-arginyl-arginyl-tryptophyl-tryptophyl-argininamide  0   *Antimicrobial Cationic Peptides. Biochim Biophys Acta 2009 Mar;1788(3):650-9
meucin-18  0   *Antimicrobial Cationic Peptides. FASEB J 2009 Apr;23(4):1230-45
meucin-13  0   *Antimicrobial Cationic Peptides. FASEB J 2009 Apr;23(4):1230-45
EFK17 peptide  0   *Antimicrobial Cationic Peptides. Antimicrob Agents Chemother 2009 Feb;53(2):593-602
hydramacin-1, Hydra magnipapillata  0   *Antimicrobial Cationic Peptides. J Biol Chem 2009 Jan 16;284(3):1896-905
ixosin protein, Ixodes sinensis  0   *Salivary Proteins and Peptides *Antimicrobial Cationic Peptides. Peptides 2006 Jan;27(1):31-5
aurein 2.5 peptide, Litoria aurea  0   *Antimicrobial Cationic Peptides. Regul Pept 2005 May 15;128(1):75-83
paenibacillin N  0   *Antimicrobial Cationic Peptides. Biochem Biophys Res Commun 2009 Feb 6;379(2):179-85
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy