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Simaroubaceae

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Definition: A plant family of the order Sapindales, subclass Rosidae, class Magnoliopsida. Leaves are alternate and compound. Most have small flowers, bitter bark, and fleshy fruits that are sometimes winged. Members contain QUASSINS.  prefer specific plant; coord with specific PLANT STRUCTURES term if pertinent; for use in therapy coord IM with PHYTOTHERAPY (IM) + disease/drug ther (IM) + PLANT PREPARATIONS or its indentations/ther use (IM or NIM) + specific plant chemical /ther use (   
Examples Ailanthus; Brucea; Eurycoma; Picrasma; Quassia; Simarouba 		Other names Simabas; Picrolemmas; Harrisonias; Castelas; Picrolemma; Simaba; Harrisonia; Castela
 
SubstanceCAS Registry & nameCategoriesSource
cedronolactone E  0   *Quassins Simaroubaceae. J Nat Prod 2001 Dec;64(12):1583-4
samaderin B  0   *Quassins Simaroubaceae. Fitoterapia 2001 Jun;72(5):568-71
samaderin C  0   *Quassins Simaroubaceae. Fitoterapia 2001 Jun;72(5):568-71
samaderin A  0   *Quassins Simaroubaceae. Fitoterapia 2001 Jun;72(5):568-71
indaquassin C  0   *Quassins Simaroubaceae. Fitoterapia 2001 Jun;72(5):568-71
ailantinol B  0   *Quassins Simaroubaceae Ailanthus. J Nat Prod 1996 Jul;59(7):683-6
ailantinol A  0   *Quassins Simaroubaceae Ailanthus. J Nat Prod 1996 Jul; 59(7):683-6
polyandrol  0   *Quassins Simaroubaceae. Phytochemistry 1995 Apr;38(6):1463-5
cedronolin  0   *Quassins Simaroubaceae. J Ethnopharmacol 1994 Jun;43(1):57-61
cedronin  111567-19-2   *Quassins Simaroubaceae. J Ethnopharmacol 1994 Jun;43(1):57-61
gutolactone  152369-48-7   *Quassins Simaroubaceae. J Nat Prod 1993 Nov;56(11):1954-61
isobrucein B  53663-03-9   *Quassins Simaroubaceae. J Nat Prod 1992 May;55(5):667-71
bruceanic acid A methyl ester  53663-08-4 3,10-Ethano-1H,8H-furo(3,4-d)(1)benzopyran-9-acetic acid, 8-acetyl-4-((3,4-dimethyl-1-oxo-2-pentenyl)oxy)octahydro-11,12-dihydroxy-3-(methoxycarbonyl)-9-methyl-5-oxo-, methyl ester, (3S-(3alpha,3aalpha,4alpha(E),6aalpha,8alpha,9beta,10alpha,10aS*,11S*,12  *Quassins Simaroubaceae Brucea. J Nat Prod 1990;53(6):1526
bruceanic acid A  53663-07-3 3,10-Ethano-1H,8H-furo(3,4-d)(1)benzopyran-9-acetic acid, 8-acetyl-4-((3,4-dimethyl-1-oxo-2-pentenyl)oxy)octahydro-11,12-dihydroxy-3-(methoxycarbonyl)-9-methyl-5-oxo-, (3S-(3alpha,3aalpha,4alpha(E),6aalpha,8alpha,9beta,10alpha,10aS*,11S*,12R))  *Quassins Simaroubaceae Brucea. J Nat Prod 1990;53(6):1526
SUN 0237  87790-39-4 Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-15-((1-oxo-2-undecenyl)oxy)-, (1beta,11beta,12alpha,15beta(E))  *Quassins Simaroubaceae Ailanthus. Anticancer Res 1988;8(4):573
chaparrin  4616-50-6   *Quassins Simaroubaceae. Arch Invest Med (Mex) 1986;17 Suppl 1:127
13,18-dehydro-6alpha-senecioyloxychaparrin  103839-22-1   *Quassins Simaroubaceae. J Nat Prod 1986;49(3):440
12-dehydro-6alpha-senecioyloxychaparrin  103850-77-7   *Quassins Simaroubaceae. J Nat Prod 1986;49(3):440
sergeolide  82290-17-3 3,13-Ethano-1H,10H-furo(3,4-c)furo(2',3':6,7)naphtho(2,3-b)pyran-3(3aH)-carboxylic acid, 4-(acetyloxy)-4,5,6a,7,7a,8,12a,13-octahydro-14,15-dihydroxy-8,12a-dimethyl-5,10-dioxo-, methyl ester, (3S-(3alpha,3aalpha,4alpha,6aalpha,7abeta,8beta,12a))  *Quassins Simaroubaceae. Planta Med 1985;(1):20
isoquassinic acid  89678-55-7   *Quassins Simaroubaceae. Anal Biochem 1984;136(1):145
6 alpha-senecioyloxychaparrin  82151-95-9 Picras-3-en-16-one, 11,20-epoxy-1,2,11,12-tetrahydroxy-6-((3-methyl-1-oxo-2-butenyl)oxy)-, (1beta,2alpha,6alpha,11beta,12alpha)  *Quassins Simaroubaceae. J Nat Prod 1983;46(2):218
bisbrusatolyl malonate  80096-78-2 Picras-3-en-21-oic acid, 3,3'-((1,3-dioxo-1,3-propanediyl)bis(oxy))bis(13,20-epoxy-11,12-dihydroxy-15-((3-methyl-1-oxo-2-butenyl)oxy)-2,16-dioxo-, dimethyl ester, (11beta,12alpha,15beta)-(11'beta,12'alpha,15'beta)-)  *Quassins Simaroubaceae Brucea. J Pharm Sci 1982;71(2):257
ailanthone  981-15-7 Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1beta,11beta,12alpha)  *Quassins Simaroubaceae. Farmaco (Sci) 1981;36(2):116
simarolide  1260-58-8   *Quassins Simaroubaceae. Biochem Biophys Res Commun 1980;93(3):675
soulameanone  74133-46-3 Picras-3-ene-2,16-dione, 1,11,12,13,15-pentahydroxy-, (1beta,11beta,12alpha,15beta)  *Quassins Simaroubaceae. Biochem Biophys Res Commun 1980;93(3):675
simalikalactone D  35321-80-3 Picras-3-ene-2,16-dione, 13,20-epoxy-1,11,12-trihydroxy-15-(2-methyl-1-oxobutoxy)-, (11beta)  *Quassins Cell Transformation, Viral/drug effects Simaroubaceae. Biochem Biophys Res Commun 1980;93(3):675
soularubinone  74156-49-3 Picras-3-ene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-15-(3-hydroxy-3-methyl-1-oxobutoxy)-, (1beta,11beta,12alpha,15beta)  *Quassins Cell Transformation, Viral/drug effects Simaroubaceae. Biochem Biophys Res Commun 1980;93(3):675
castelanone  70424-54-3 Picras-3-ene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-15-(3-methyl-1-oxobutoxy)-, (1beta,11beta,12alpha,15beta)  *Quassins Cell Transformation, Viral/drug effects Simaroubaceae. Biochem Biophys Res Commun 1980;93(3):675
chaparrinone  22611-34-3 Picras-3-ene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-, (1beta,11beta,12alpha)  *Quassins Cell Transformation, Viral/drug effects Simaroubaceae. Biochem Biophys Res Commun 1980;93(3):675
6 alpha-tigloyloxychaparrinone  69423-71-8   *Quassins Simaroubaceae Ailanthus. J Natural Prod 41(6):584;1978
6 alpha-senecioyloxychaparrinone  68499-52-5   *Quassins Simaroubaceae. J Nat Prod 41(6):578;1978
13,18-dehydroglaucarubinone  68703-94-6 Picrasa-3,13(21)-diene-2,16-dione, 1,11,12-trihydroxy-15-(2-hydroxy-2-methyl-1-oxobutoxy)-, (1beta,11beta,12alpha,15beta(S))  Glaucarubin/*analogs & derivatives Simaroubaceae. Experientia 34(9):1122;1978
simaroubolide  56093-51-7   *Quassins Simaroubaceae. Proc Life Sci: New Nat Prod Plant Drugs Pharm Biol Ther W3 In 632n1.st:60;1976n
holacanthone  77648-51-2 Picrasane-2,16-dione, 15-(acetyloxy)-11,20-epoxy-1,11,12-trihydroxy-, (1beta,4beta,11beta,12alpha,15beta)  *Quassins Simaroubaceae. Cancer Treat Rep 60(8):1024;1976
quassimarin  59938-97-5   *Quassins Simaroubaceae. J Org Chem 41(21):3481;1976
dehydroailanthinone  53683-70-8   *Quassins Simaroubaceae Ailanthus. J Org Chem 40(5):654;1975
quassin  76-78-8   *Quassins Simaroubaceae. Fortschr Chem Org Naturst 30:102;1973; Helv Chim Acta 58(6):1727;1975

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