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Brucea

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Definition: A plant genus of the family SIMAROUBACEAE. Members contain bruceosides and bruceanols (quassinoids). The astringent seeds have been used to treat dysentery in southeastern Asia.  coord with specific PLANT STRUCTURES term if pertinent; for use in therapy coord IM with PHYTOTHERAPY (IM) + disease/drug ther (IM) + PLANT PREPARATIONS or its indentations/ther use (IM or NIM) + specific plant chemical /ther use (IM) if pertinent; Manua    Other names Bruceas
 
SubstanceCAS Registry & nameCategoriesSource
dehydrobrusatol  0   *Quassins Brucea. J Nat Prod 2001 Dec;64(12):1509-13
yadanziolide C  0   *Quassins Brucea. J Nat Prod 2001 Dec;64(12):1509-13
bruceanol H  168569-27-5   *Quassins Brucea. J Nat Prod 1995 Dec;58(12):1915-9
bruceanol G  168301-20-0   *Quassins Brucea. J Nat Prod 1995 Dec;58(12):1915-9
bruceoside F  0   *Quassins Brucea. J Nat Prod 1995 Jul;58(7):1032-8
bruceoside E  0   *Quassins Brucea. J Nat Prod 1995 Jul;58(7):1032-8
bruceoside D  0   *Quassins Brucea. J Nat Prod 1995 Jul;58(7):1032-8
bruceanol F  101910-72-9 Picras-2-en-21-oic acid, 15-((3,4-dimethyl-1-oxo-2-pentenyl)oxy)-13,20-epoxy-2,11,12-trihydroxy-1,16-dioxo-, methyl ester, (11beta,12alpha,15beta(E))  *Quassins Brucea. J Nat Prod 1993 Dec;56(12):2091-7
bruceanol E  152645-85-7 Picrasan-21-oic acid, 15-((3,4-dimethyl-1-oxo-2-pentenyl)oxy)-13,20-epoxy-1,11,12-trihydroxy-2,16-dioxo-, methyl ester, (1beta,11beta,12alpha,15beta(E))  *Quassins Brucea. J Nat Prod 1993 Dec;56(12):2091-7
bruceanol D  152645-84-6 Picras-3-en-21-oic acid, 15-((3,4-dimethyl-1-oxo-2-pentenyl)oxy)-13,20-epoxy-1,11,12-trihydroxy-2,16-dioxo-, methyl ester, (1beta,11beta,12alpha,15beta(E))  *Quassins Brucea. J Nat Prod 1993 Dec;56(12):2091-7
bruceoside C  141271-79-6   *Quassins Brucea. J Nat Prod 1992 Apr;55(4):468-75
bruceanic acid A methyl ester  53663-08-4 3,10-Ethano-1H,8H-furo(3,4-d)(1)benzopyran-9-acetic acid, 8-acetyl-4-((3,4-dimethyl-1-oxo-2-pentenyl)oxy)octahydro-11,12-dihydroxy-3-(methoxycarbonyl)-9-methyl-5-oxo-, methyl ester, (3S-(3alpha,3aalpha,4alpha(E),6aalpha,8alpha,9beta,10alpha,10aS*,11S*,12  *Quassins Simaroubaceae Brucea. J Nat Prod 1990;53(6):1526
bruceanic acid D  132587-61-2 3,10-Ethano-1H,8H-furo(3,4-d)(1)benzopyran-9-acetic acid, 8-acetyloctahydro-11,12-dihydroxy-4-((4-hydroxy-3,4-dimethyl-1-oxo-2-pentenyl)oxy)-3-(methoxycarbonyl)-9-methyl-5-oxo-, (3S-(3alpha,3aalpha,4alpha(E),6aalpha,8alpha,9beta,10alpha,10aS ))  *Quassins Brucea. J Nat Prod 1990;53(6):1526
bruceanic acid C  132587-60-1 3,10-Ethano-1H,8H-furo(3,4-d)(1)benzopyran-9-acetic acid, 8-acetyl-4-((4-(acetyloxy)-3,4-dimethyl-1-oxo-2-pentenyl)oxy)octahydro-11,12-dihydroxy-3-(methoxycarbonyl)-9-methyl-5-oxo-, (3S-(3alpha,3aalpha,4alpha(E),6aalpha,8alpha,9beta,10alpha,))  *Quassins Brucea. J Nat Prod 1990;53(6):1526
bruceanic acid B  132616-54-7 3,10-Ethano-1H,8H-furo(3,4-d)(1)benzopyran-9-acetic acid, 8-acetyl-4-(benzoyloxy)octahydro-11,12-dihydroxy-3-(methoxycarbonyl)-9-methyl-5-oxo-, (3S-(3alpha,3aalpha,4alpha,6aalpha,8alpha,9beta,10alpha,10aS*,11S*,12R*))  *Quassins Brucea. J Nat Prod 1990;53(6):1526
bruceanic acid A  53663-07-3 3,10-Ethano-1H,8H-furo(3,4-d)(1)benzopyran-9-acetic acid, 8-acetyl-4-((3,4-dimethyl-1-oxo-2-pentenyl)oxy)octahydro-11,12-dihydroxy-3-(methoxycarbonyl)-9-methyl-5-oxo-, (3S-(3alpha,3aalpha,4alpha(E),6aalpha,8alpha,9beta,10alpha,10aS*,11S*,12R))  *Quassins Simaroubaceae Brucea. J Nat Prod 1990;53(6):1526
yadanzioside F  95258-11-0   *Quassins Brucea. Yakugaku Zasshi 1990;110(11):834
bruceoside B  69687-69-0   *Quassins Brucea. Yakugaku Zasshi 1990;110(11):834
bruceine I  130705-31-6 Picras-3-en-21-oic acid, 13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, ethyl ester, (11beta,12alpha)  *Quassins Drugs, Chinese Herbal Brucea. Yao Hsueh Hsueh Pao 1990;25(5):382
yadanzioside M  101559-99-3 Picras-1-en-21-oic acid, 15-(benzoyloxy)-13,20-epoxy-2-(beta-D-glucopyranosyloxy)-11,12-dihydroxy-3,16-dioxo-, methyl ester, (11beta,12alpha,15beta)  *Quassins Brucea. J Nat Prod 1989;52(2):398
bruceanol C  114586-21-9 Picras-3-en-21-oic acid, 15-((4-(acetyloxy)-3,4-dimethyl-1-oxo-2-pentenyl)oxy)-13,20-epoxy-1,11,12-trihydroxy-2,16-dioxo-, methyl ester, (1beta,11beta,12alpha,15beta(E))  *Quassins Brucea. J Nat Prod 1988;51(2):349
bruceantinoside C  112899-35-1 Picras-2-en-21-oic acid, 15-((4-(acetyloxy)-3,4-dimethyl-1-oxo-2-pentenyl)oxy)-13,20-epoxy-2-(beta-D-glucopyranosyloxy)-11,12-dihydroxy-1,16-dioxo-, methyl ester, (11beta,12alpha,15beta(E))  *Quassins Brucea. J Nat Prod 1987;50(6):1075
bruceanol A  101391-06-4 Picras-3-en-21-oic acid, 15-(benzoyloxy)-13,20-epoxy-1,11,12-trihydroxy-2,16-dioxo-, methyl ester, (1beta,11beta,12alpha,15beta)  *Quassins Brucea. J Nat Prod 1985;48(6):972
bruceanol B  101391-05-3 Picras-3-en-21-oic acid, 13,20-epoxy-1,11,12-trihydroxy-2,16-dioxo-15-((1-oxopentyl)oxy)-, methyl ester, (1beta,11beta,12alpha,15beta)  *Quassins Brucea. J Nat Prod 1985;48(6):972
bisbrusatolyl malonate  80096-78-2 Picras-3-en-21-oic acid, 3,3'-((1,3-dioxo-1,3-propanediyl)bis(oxy))bis(13,20-epoxy-11,12-dihydroxy-15-((3-methyl-1-oxo-2-butenyl)oxy)-2,16-dioxo-, dimethyl ester, (11beta,12alpha,15beta)-(11'beta,12'alpha,15'beta)-)  *Quassins Simaroubaceae Brucea. J Pharm Sci 1982;71(2):257
bruceantinoside B  79439-84-2 Picras-3-en-21-oic acid, 15-((3,4-dimethyl-1-oxo-2-pentenyl)oxy)-13,20-epoxy-3-(beta-D-glucopyranosyloxy)-11,12-dihydroxy-2,16-dioxo-, methyl ester, (11beta,12alpha,15beta(E))  *Quassins Brucea. J Nat Prod 1981;44(4):470
bruceantinoside A  79439-85-3 Picras-1-en-21-oic acid, 15-((3,4-dimethyl-1-oxo-2-pentenyl)oxy)-13,20-epoxy-2-(beta-D-glucopyranosyloxy)-11,12-dihydroxy-3,16-dioxo-, methyl ester, (11beta,12alpha,15beta(E))  *Quassins Brucea. J Nat Prod 1981;44(4):470
bruceine E  21586-90-3 Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1beta,2alpha,11beta,12alpha,15beta)  *Quassins Brucea. Yao Hsueh Hsueh Pao 1981;16(3):53
bruceine D  21499-66-1 Picras-3-ene-2,16-dione, 13,20-epoxy-1,11,12,14,15-pentahydroxy-, (1beta,11beta,12alpha,15beta)  *Quassins Brucea. Yao Hsueh Hsueh Pao 1981;16(3):53
bruceine B  25514-29-8   *Quassins Cell Transformation, Viral/drug effects Brucea. Biochem Biophys Res Commun 1980;93(3):675
bruceine A  25514-31-2   *Quassins Cell Transformation, Viral/drug effects Brucea. Biochem Biophys Res Commun 1980;93(3):675; J Pharm Pharmacol 1979;31(Suppl):10P
dehydrobruceine A  73435-47-9 Picrasa-1,4-dien-21-oic acid, 13,20-epoxy-2,11,12-trihydroxy-15-(3-methyl-1-oxobutoxy)-3,16-dioxo-, methyl ester, (11beta,12alpha,15beta)  *Quassins Brucea. J Pharm Pharmacol 31(Suppl):10P;1979
brusatol  14907-98-3 (11 beta,12 alpha,15 beta)-13,20-epoxy-3,11,12- trihydroxy-15-((3-methyl-1-oxo-2-butenyl)oxy)- 2,16-dioxopicras-3-en-21-oic acid, methyl ester  *Quassins Brucea. J Pharm Sci 68(7):201;1979; J Pharm Sci 68(7):883;1979
bruceoside A  63306-30-9   *Quassins Brucea. J Pharm Sci 68(7):201;1979; J Pharm Sci 68(7):883;1979
bruceantarin  41451-76-7   *Quassins Brucea. J Org Chem 38(1):178;1972; J Pharm Pharmacol 1979;31(Suppl):10P
bruceantin  41451-75-6   *Quassins Brucea. Biochim Biophys Acta 518:104;1978; Cancer Chemother Pharmacol 1(2):91;1978; Cancer Chemother Pharmacol 1979;3(3):171; Cancer Treat Rep 1979;63(11-12):1843; Cancer Treat Rep 1979;63(11-12):1929; Cancer Treatment Rep 60(8):1127;1976; J Org Chem 38(1):178;1972; J Pharm Pharmacol 1979;31(Suppl):10P; J Pharm Sci 68(7):201;1979; Molec Pharmacol 12(1):167;1976; Proc Life Sci New Nat Prod Plant Drugs Pharm Biol Ther W3 IN 632M 1:60;1976

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