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Fumonisins

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Definition: A group of MYCOTOXINS found in CORN contaminated with FUSARIUM fungus. They are chains of about 20 carbons with acidic ester, acetylamino and sometimes other substituents. They inhibit ceramide synthetase conversion of SPHINGOLIPIDS to CERAMIDES.     
Pharmacological Action Poisons
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
fumonisin B6  0   *Fumonisins. J Agric Food Chem. 2010 Jan 27;58(2):949-53
fumonisin C3  0   *Fumonisins Mycotoxins. J Nat Prod 1996 Nov;59(11):1003-9
fumonisin FP3  0   *Pyridines *Fumonisins Mycotoxins. J Nat Prod 1996 Oct;59(10):970-2
fumonisin FP2  0   *Pyridines *Fumonisins Mycotoxins. J Nat Prod 1996 Oct;59(10):970-2
fumonisin FP1  0   *Pyridines *Fumonisins Mycotoxins. J Nat Prod 1996 Oct;59(10):970-2
fumonisin A2  117415-47-1   *Fumonisins Mycotoxins. Vet Hum Toxicol 1994 Dec;36(6):548-55
fumonisin A1  117415-48-2   *Fumonisins Mycotoxins. Vet Hum Toxicol 1994 Dec;36(6):548-55
fumonisin B4  136379-60-7   *Fumonisins Mycotoxins. Mycopathologia 1992 Feb;117(1-2):3-9
fumonisin B3  136379-59-4 1,2,3-Propanetricarboxylic acid, 1,1'-(1-(12-amino-4,11-dihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) ester  *Fumonisins Mycotoxins.
Pharma Action Carcinogens, Environmental
Appl Environ Microbiol 1992 Jan;58(1):169-73
fumonisin B2  116355-84-1 1,2,3-Propanetricarboxylic acid, 1,1'-(1-(12-amino-9,11-dihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) ester  *Fumonisins Mycotoxins.
Pharma Action Carcinogens, Environmental
Appl Environ Microbiol 1988;54(7):1806
fumonisin B1  116355-83-0 1,2,3-Propanetricarboxylic acid, 1,1'-(1-(12-amino-4,9,11-trihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) ester  *Fumonisins Mycotoxins.
Pharma Action Carcinogens, Environmental ; Enzyme Inhibitors ; Teratogens
Appl Environ Microbiol 1988;54(7):1806

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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