encyclopedia of medical concepts
ψ 

Steryl-Sulfatase

More information in Books or onNLM PubMed
Definition: An arylsulfatase with high specificity towards sulfated steroids. Defects in this enzyme are the cause of ICHTHYOSIS, X-LINKED.      Other names Sulphatase, Steroid; Sulfohydrolase, Steroid; Sulfohydrolase, Estrone Sulfate; Sulfate Sulfohydrolase, Estrone; Sulfate Sulfatase, Estrone; Sulfate Sulfatase, Dehydroepiandrosterone; Sulfate Sulfatase, Cholesterol; Sulfatase, Sterol; Sulfatase, Steroid; Sulfatase, Estrone Sulfate; Sulfatase, Dehydroepiandrosterone Sulfate; Sulfatase, DHEA; Sulfatase, Cholesterol Sulfate; Sulfatase, Cholesterol; Steryl Sulfatase; 3 Beta Hydroxysteroid Sulfate Sulfatase; Sterylsulfatase; Sterol Sulfatase; Steroid Sulphatase; Steroid Sulfohydrolase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
estradiol-3-O-sulfamate  0   Estradiol/*analogs & derivatives Steryl-Sulfatase/antagonists & inhibitors. Hum Reprod 2011 Jun;26(6):1362-70
STX289  0   *Sulfonic Acids Steryl-Sulfatase/antagonists & inhibitors. Anticancer Res 2008 May-Jun;28(3A):1517-23
KW 2581  0   *Sulfonamides Estradiol/*analogs & derivatives Steryl-Sulfatase/antagonists & inhibitors. Breast Cancer Res Treat 2007 Aug;104(2):211-9
sulfamic acid 5-(((4-cyanophenyl)(1,2,4)triazol-4-ylamino)methyl)-2-fluorophenyl ester  0   *Sulfonamides *Triazoles Steryl-Sulfatase/antagonists & inhibitors. J Med Chem 2007 Jul 26;50(15):3540-60
sulfamic acid 2-bromo-4-(((4-cyanophenyl)(1,2,4)triazol-4-ylamino)methyl)phenyl ester  0   *Sulfonamides *Triazoles Steryl-Sulfatase/antagonists & inhibitors. J Med Chem 2007 Jul 26;50(15):3540-60
STX64 compound  0   *Sulfonic Acids Steryl-Sulfatase/antagonists & inhibitors. Oncologist 2007 Apr;12(4):370-4
STX 213  0   *Azasteroids Steryl-Sulfatase/antagonists & inhibitors. Clin Cancer Res 2006 Sep 15;12(18):5543-9
2-adamantan-1-yl-4-oxo-4H-thiochromene-6-carboxylic acid  0   *Chromones Adamantane/*analogs & derivatives Steryl-Sulfatase/antagonists & inhibitors. J Med Chem 2004 Aug 12;47(17):4268-76
adamantan-1-yl-4-oxo-4H-chromene-6-carboxylic acid  0   *Chromones Adamantane/*analogs & derivatives Steryl-Sulfatase/antagonists & inhibitors. J Med Chem 2004 Aug 12;47(17):4268-76
2',4'-dicyanobiphenyl-4-O-sulfamate  0   *Biphenyl Compounds *Sulfonic Acids Steryl-Sulfatase/antagonists & inhibitors. J Steroid Biochem Mol Biol. 2004 Feb;88(2):167-73

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy