encyclopedia of medical concepts
ψ 

Azasteroids

More information in Books or onNLM PubMed
Definition: Steroidal compounds in which one or more carbon atoms in the steroid ring system have been substituted with nitrogen atoms.     
Examples Finasteride
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-fluoro-N-(3H-imidazo(4,5-b)pyridin-2-ylmethyl)-1,4a,6a-trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno(5,4-f)quinoline-7-carboxamide  0   *Azasteroids. J Biol Chem 2010 May 28;285(22):17054-64
3-hydroxy-17a-azahomoandrostan-7-one-4-N,N-bis(2-chloroethyl)aminophenyl acetate  0   *Azasteroids *Nitrogen Mustard Compounds. Mutat Res 2009 Apr 30;675(1-2):51-9
3-hydroxy-3-aza-A-homoandrosten-4-one-4-bis(2-chloroethyl)aminophenoxyacetate  0   *Azasteroids *Nitrogen Mustard Compounds. Cancer Lett 2006 Nov 18;243(2):202-10
3-hydroxy-13-amino-13,17-secoandrostan-17-oic-13,17-lactam p-bis(2-chloroethyl)amino phenyl acetate  0   *Azasteroids *Secosteroids. Breast Cancer Res Treat 2006 May;97(1):17-31
STX 213  0   *Azasteroids Steryl-Sulfatase/antagonists & inhibitors. Clin Cancer Res 2006 Sep 15;12(18):5543-9
2'-(4-fluorophenyl)-4-azapyrazolo(4',3'-2,3)androstan-17-ol  0   *Azasteroids. Acta Crystallogr C 2003 Dec;59(Pt 12):o724-6
2'-(4-fluorophenyl)-4-azapyrazolo(4',3'-2,3)androstan-17-yl acetate  0   *Azasteroids. Acta Crystallogr C 2003 Dec;59(Pt 12):o724-6
2,3-dimethoxy-8-azagona-1,3,5(10),13-tetraene-12,17-dione  0   *Azasteroids. Biopolymers 2004 May-Jun 5;74(1-2):105-9
N-(1-(4-methoxyphenyl)-1-methylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide  0   *Androstenes *Azasteroids. Int J Pharm 2003 Apr 14;255(1-2):69-79
3-hydroxy-13-amino-13,17-seco-5alpha-androstan-17-oic-13,17-lactam 2-N,N-bis(2-chloroethyl)aminobenzoate  157757-66-9   *Azasteroids *Nitrogen Mustard Compounds. Chemotherapy 1999 Jan-Feb;45(1):61-7
L 751788  0   *Azasteroids Dihydrotestosterone/*analogs & derivatives. J Chromatogr B Biomed Sci Appl 1998 Aug 25;713(2):371-8
8,13-diaza-2,3-dimethoxygona-1,3,5(10),9(11)-tetraen-12-one  0   *Azasteroids. Steroids 1998 Jul-Aug;63(7-8):375-82
dutasteride  0   *Azasteroids Prostatic Hyperplasia.
Pharma Action 5-alpha Reductase Inhibitors 		J Pharmacol Exp Ther 1997 Sep;282(3):1496-502DUTASTERIDE; AVODART; JALYN
N-4(benzylbenzoyl)-3-oxo-4-aza-4-methyl-5-androstane-17-carboxamide  0   *Androstanes *Azasteroids. Steroids 1996 May;61(5):323-31
6,7-diazacholest-8(14)-en-3-ol  0   *Azasteroids Cholesterol/*analogs & derivatives. Biochemistry 1996 Jun 4;35(22):7069-76
6-aza-B-homocholest-7-en-3-ol  0   *Azasteroids Cholesterol/*analogs & derivatives. Biochemistry 1996 Jun 4;35(22):7069-76
7a,17a-diaza-7,17-dioxo-B,D-dihomo-5-androsten-3-yl 4-N,N-bis(2-chloroethyl)aminophenylacetate  0   *Azasteroids *Homosteroids. Anticancer Res 1995 May-Jun;15(3):827-30
4,7beta-dimethyl-4-azacholestan-3-one  0   *Azasteroids.
Pharma Action 5-alpha Reductase Inhibitors 		J Med Chem 1994 Nov 11;37(23):3871-4
L 651723  0   *Androstenes *Azasteroids 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. Biol Reprod 1994 Jun;50(6):1244-50
FCE 28260  155651-56-2   *Androstenes *Azasteroids 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. J Steroid Biochem Mol Biol 1994 Jun;49(4-6):289-94
FCE 28175  156990-25-9   *Androstenes *Azasteroids 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. J Steroid Biochem Mol Biol 1994 Jun;49(4-6):289-94
FCE 27837  155651-61-9   *Androstenes *Azasteroids 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. J Steroid Biochem Mol Biol 1994 Jun;49(4-6):289-94
16-oxo-17-azaandrost-5-en-3-ol acetate  0   *Androstenols *Azasteroids. Steroids 1994 Jan;59(1):30-3
ANQ 9040  0   *Androstanes *Azasteroids. Anesthesiology 1994 Jan;80(1):97-103
UCA 1064-B  144773-49-9   Azasteroids. J Antibiot (Tokyo) 1993 Aug;46(8):1312-4
3-methoxy-17-aza-homoandrost-5-ene-17-one  84300-23-2   *Androstenols *Azasteroids. Steroids 1993 Apr;58(4):181-4
3-hydroxy-N-methyl-17-aza-D-homoandrostan-17-one-4-N,N-bis(2-chloroethyl)aminophenylacetate  146678-52-6   *Androstanes *Azasteroids *Nitrogen Mustard Compounds. Anticancer Res 1992 Sep-Oct;12(5):1617-20
3-hydroxy-17-aza-D-homoandrostan-4-N,N-bis(2-chloroethyl)aminophenylacetate  146678-51-5   *Androstanes *Azasteroids *Nitrogen Mustard Compounds. Anticancer Res 1992 Sep-Oct;12(5):1617-20
(5alpha)-23-methyl-4-aza-21-norchol-1-ene-3,20-dione  103497-68-3 4-Aza-21-norchol-1-ene-3,20-dione, 23-methyl-, (5alpha)  *Azasteroids 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. Clin Pharmacol Ther1992 Oct;52(4):409-12
N,N-diethyl-4-methoxy-3-oxo-4-aza-5-androstene-17-carboxamide  106649-71-2   *Androstenes *Azasteroids 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. Int J Androl 1991 Oct;14(5):359-63
N-chloro-3-methoxy-16-aza-1,3,5(10)-estratrien-17-one  114462-28-1   *Azasteroids *Estrenes. Acta Crystallogr B 1991;47(Pt 3):383
N-chloro-3-methoxy-17-aza-homo-1,3,5(10)-estratrien-17-one  114462-29-2   *Azasteroids *Estrenes. Acta Crystallogr B 1991;47(Pt 3):383
N-chloro-3-methoxy-17-azahomo-1,3,5(10)-estratrien-16-one  119111-52-3   *Azasteroids *Estrenes. Acta Crystallogr B 1991;47(Pt 3):383
NSC 620480  89043-18-5   *Azasteroids *Nitrogen Mustard Compounds. Methods Find Exp Clin Pharmacol 1990;12(7):501
D-11-aza-19-nortestosterone  41235-53-4 11-Azaestr-4-en-3-one, 17-hydroxy-, (17beta)  *Azasteroids *Nandrolone. Bioorg Khim 1988;14(3):392
2,3-bisaza-A-nor-1,5(10)-estradien-17-ol  89288-70-0   *Azasteroids *Estrenes. Steroids 1986;48(3-4):213
17-acetamido-3-aza-A-homo-4-androsten-4-one  93176-75-1   *Androstenes *Azasteroids. Cancer Invest 1987;5(4):301
L 636028  104199-89-5   *Androstanes *Azasteroids. J Endocrinol 1987 Feb;112(2):189-95
17-hydroxy-4-aza-A-nor-5-androsten-3-one (4-N,N-bis(2-chloroethylamino)phenyl)butyrate  107534-94-1   *Azasteroids Chlorambucil/*analogs & derivatives. Oncology 1986;43(6):390
3-hydroxy-13,17-seco-5-androsten-17-oic-13,17-lactam (4-(bis(2-chloroethyl)amino)phenyl)butyrate  107480-21-7   *Azasteroids Chlorambucil/*analogs & derivatives. Oncology 1986;43(6):344
3-hydroxy-13,17-secoandrostan-17-oic-13,17-lactam (4-(bis(2-chloroethyl)amino)phenyl)butyrate  68426-41-5   *Azasteroids Chlorambucil/*analogs & derivatives. Oncology 1986;43(6):344
17-hydroxy-3-aza-A-homo-4-androsten-4-one (4-(bis(2-chloroethyl)amino)phenyl)butyrate  99876-94-5   *Azasteroids Chlorambucil/*analogs & derivatives. Oncology 1986;43(6):344
17-N,N-diisopropylcarbamoyl-4-azaandrostan-3-one  89631-79-8   *Azasteroids Dihydrotestosterone/*analogs & derivatives 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. Endocrinology 1986 Jan;118(1):132-7
25-azacoprostane  37106-88-0 Cholan-24-amine, N,N-dimethyl-, (5beta)  *Azasteroids. Comp Biochem Physiol B 1985;82(1):99
21-diazo-4-methyl-4-azapregnane-3,20-dione  96692-00-1   *Azasteroids *Pregnanediones. J Biol Chem 1985;260(8):4890
4-aza-4-methylpregnane-3,20-dione  73671-90-6 4-Azapregnane-3,20-dione, 4-methyl-, (5alpha)  *Azasteroids *Pregnanediones. Endocrinology 1984;114(1):63
17-aza-homo-delta (1,3,5(10)) estratrien-3-ol-17-one-4-N,N-bis(2-chloroethyl)aminophenylacetate  87777-66-0 17a-Aza-D-homoestra-1,3,5(10)-trien-17-one, 3-(((4-(bis(2-chloroethyl)amino)phenyl)acetyl)oxy)  *Azasteroids *Nitrogen Mustard Compounds. Methods Find Exp Clin Pharmacol1983;5(6):365
4-methyl-4-aza-3-oxopregnane-20-carboxylate  92472-61-2 4-Azapregnane-20-carboxylic acid, 4-methyl-3-oxo-, sodium salt, (5alpha,20S)  *Azasteroids *Pregnanes.
Pharma Action 5-alpha Reductase Inhibitors 		J Steroid Biochem 1983;18(3):365
3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstan-17-oic-13,17-lactam  39932-99-5 17a-Aza-D-homoandrostan-17-one, 3-hydroxy-, (3beta,5alpha)  *Androstanes *Azasteroids. Methods Find Exp Clin Pharmacol 1982 Aug-Sep;4(6):403-6
3-(((4-(bis(2-chloroethyl)amino)phenyl)acetyl)oxy)-17a-aza-D-homoandrost-5-en-17-one  53039-94-4   *Azasteroids *Nitrogen Mustard Compounds. Oncology 1982;39(1):59
RU 5135  78774-26-2 17-Azaandrost-16-en-11-one, 16-amino-3-hydroxy-, (3alpha,5beta)  *Androstanes *Azasteroids.
Pharma Action GABA Antagonists 		Neuropharmacology 1981;20(4):357
17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one  73671-86-0 4-Azaandrostane-17-carboxamide, N,N-diethyl-4-methyl-3-oxo-, (5alpha,17beta)  *Azasteroids Dihydrotestosterone/*analogs & derivatives.
Pharma Action Androgen Antagonists ; 5-alpha Reductase Inhibitors 		J Biol Chem 1981 Aug;256(15):7998-8005
4-methyl-4-azacholestane  1867-76-1 4-Azacholestane, 4-methyl-, (5alpha)  *Azasteroids *Cholestanes. J Steroid Biochem 1980;13(6):685
samandarone  467-52-7 3-aza-A-homoandrostan-16-one, 1,4-epoxy-, (1 alpha,4 alpha,5 beta)  *Androstanes *Azasteroids. Yakugaku Zasshi 1980;100(3):227
samanine  22614-24-0 3-aza-A-homoandrostan-16-ol, (5 beta,16 beta)  *Androstanols *Azasteroids. Yakugaku Zasshi 1980;199(3):227
cycloneosamandaridine  63653-59-8 3-Aza-3,6-cyclo-A-homopregnan-21-oic acid, 6,16-dihydroxy-, gamma-lactone, (3alpha,5beta,6beta,16beta)  *Azasteroids. Yakugaku Zasshi 1980;100(3):227
N-cyano-2-aza-A-norandrostan-17-ol acetate  68922-89-4 2-Aza-A-norandrostane-2-carbonitrile, 17-(acetyloxy)-, (5alpha,17beta)  *Androstanols *Azasteroids. J Med Chem 1979 Jan;22(1):119-20
NSC 290205  43000-65-3   *Azasteroids *Nitrogen Mustard Compounds. Cancer Chemother Rep 1979;3(1):67; Cancer Chemother Rep 57(3):365;1973; Cancer Treat Rep 61(1):317;1977; J Steroid Biochem 9(7):599;1978; Pharm Acta Helv 51(9):249;1976
methoxyimine  28901-18-0   *Azasteroids. Steroids 27(4):525;1976
2,10,11,11a-tetrahydro-11a-methyl-1H-naphth(1,2-g)indol-7-ol  28901-17-9   *Azasteroids *Estrenes. Steroids 27(4):525;1976; Steroids 27(4):535;1976
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy