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Secosteroids

More information in Books or onNLM PubMed
Definition: Steroids in which fission of one or more ring structures and concomitant addition of a hydrogen atom at each terminal group has occurred.     
Examples Vitamin D
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
physalin G  0   *Secosteroids. J Nat Prod. 2011 Oct 28;74(10):2269-72
malaitasterol A  0   *Secosteroids *Sterols. Org Biomol Chem 2011 Jul 7;9(13):4856-62
physalin E  0   *Secosteroids. Phytomedicine 2010 Aug;17(10):740-3
3,5-seco-4-norcholestan-5-one oxime-3-ol  0   *Oximes *Secosteroids. J Pharmacol Exp Ther 2010 Jun;333(3):696-706
3alpha-methoxy-2,3-dihydro-4,7-didehydrophysalin B  0   *Secosteroids. J Asian Nat Prod Res. 2008 Sep-Oct;10(9-10):881-5
3-hydroxy-13-amino-13,17-secoandrostan-17-oic-13,17-lactam p-bis(2-chloroethyl)amino phenyl acetate  0   *Azasteroids *Secosteroids. Breast Cancer Res Treat 2006 May;97(1):17-31
23-oxo-3,4-seco-lanosta-4(28),7(8),9(11),24(31)-tetraene-3,26-dicarboxylic acid  0   *Secosteroids. Phytochemistry 2006 Jan;67(2):202-11
withaphysalin F  0   *Secosteroids Ergosterol/*analogs & derivatives. Planta Med 2004 Jun;70(6):551-5
3beta,6beta,11-trihydroxy-9,11-seco-5alpha-cholest-7-en-9-one  0   *Secosteroids. Steroids. 2003 Oct;68(9):719-23
3beta,5alpha,6beta,11-tetrahydroxy-9,11-secocholest-7-en-9-one  0   *Secosteroids. Steroids. 2003 Oct;68(9):719-23
withaphysalin M  0   *Secosteroids Ergosterol/*analogs & derivatives. J Nat Prod 2004 Apr;67(4);710-3
withaphysalin O  0   *Secosteroids Ergosterol/*analogs & derivatives. J Nat Prod 2004 Apr;67(4);710-3
withaphysalin N  0   *Secosteroids Ergosterol/*analogs & derivatives. J Nat Prod 2004 Apr;67(4);710-3
physalin H  70241-09-7   *Secosteroids. Phytother Res 2003 May;17(5):520-3
3,11-dihydroxy-5,6-epoxy-24-methyl-9,11-secocholestan-9-one  0   *Secosteroids. J Nat Prod 2002 Sep;65(9):1357-9
pachyclavulariaenone B  0   *Secosteroids. J Nat Prod 2002 Sep;65(9):1357-9
calicoferol B  0   *Secosteroids. J Org Chem 2002 Jul 12;67(14):4821-7
tylophoriside A  0   *Saponins *Secosteroids. J Asian Nat Prod Res 2002 Sep;4(3):197-200
17-hydroxy-3-methoxy-17-phenyl-16,17-secoestra-1,3,5(10)-triene-16-nitrile  0   *Nitriles *Secosteroids. Acta Crystallogr C 2002 Feb;58(Pt 2):o63-5
3-methoxy-17-oxo-17-phenyl-16,17-secoestra-1,3,5(10)-triene-16-nitrile  0   *Nitriles *Secosteroids. Acta Crystallogr C 2002 Feb;58(Pt 2):o63-5
24-nor-9,11-seco-11-oxo-3,6-dihydroxycholesta-7,22-dien-9-one  0   *Secosteroids. Nat Prod Lett 2001;15(4):221-8
24-nor-9,11-seco-11-acetoxy-3,6-dihydroxycholesta-7,22-dien-9-one  0   *Secosteroids. Nat Prod Lett 2001;15(4):221-8
physalin D  0   *Secosteroids. J Asian Nat Prod Res 2001;3(3):199-205
physalin T  0   *Secosteroids. J Asian Nat Prod Res 2001;3(3):199-205
3-hydroxy-17-(2-((2-(N,N-dimethylamino)ethoxy)imino)ethyl)-14,15-secoandrostan-14-one  0   *Secosteroids Sodium-Potassium-Exchanging ATPase/antagonists & inhibitors. J Med Chem 2001 Nov 8;44(23):3821-30
tylopiol B  0   *Secosteroids Ergosterol/*analogs & derivatives. J Nat Prod 2000 Apr;63(4):534-6
tylopiol A  0   *Secosteroids Ergosterol/*analogs & derivatives. J Nat Prod 2000 Apr;63(4):534-6
3,7,11-trihydroxy-5,6-epoxy-9,11-secogorgostan-9-one  0   *Secosteroids. J Nat Pro 1998 Apr;61(4):538-41
luffasterol C  0   *Secosteroids *Sterols. J Nat Prod 1997 Jan;60(1):41-3
luffasterol B  0   *Secosteroids *Sterols. J Nat Prod 1997 Jan;60(1):41-3
luffasterol A  0   *Secosteroids *Sterols. J Nat Prod 1997 Jan;60(1):41-3
calicoferol E  0   *Secosteroids. J Nat Prod 1995 Aug;58(8):1291-6
calicoferol D  0   *Secosteroids. J Nat Prod 1995 Aug;58(8):1291-6
calicoferol C  0   *Secosteroids. J Nat Prod 1995 Aug;58(8):1291-6
17-hydroxy-14,15-secoandrost-4-en-15-yn-3-one  0   *Secosteroids. Steroids 1995 Mar;60(3):250-5
tylophoroside  135247-45-9 2(5H)-Furanone, 5-methoxy-5-methyl-4-01,8,9-tris(acetyloxy)-7-0(O-beta-D-glucopyranosyl-(1->4)-O-6-deoxy-3-O-methyl-alpha-L-talopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-alpha-L-lyxo-hexopyranosyl-oxy)-1,2,3,4,4a,4b,5,8,8a,9,10,10a-dodecah  *Saponins *Secosteroids. Int J Immunopharmacol 1994 Aug;16(8):641-50
3-hydroxy-5-oxo-5,6-secocholestan-6-al  81811-27-0   *Cholestanones *Secosteroids. Steroids 1993 May;58(5):225-9
hancogenin B  147512-46-7   *Secosteroids. Yao Hsueh Hsueh Pao 1992;27(8):595-602
4a,17-dimethyl-A-homo-B,19-dinor-3,4-secoandrost-9-ene-3,17-diol  145458-99-7   *Androstenediols *Secosteroids. Steroids 1992 Sep;57(9):460-3
4-methyl-4,5-secocholestane  140183-68-2   *Cholestanes *Secosteroids. Steroids 1992 Nov;57(11):551-3
4,5-secocholestane  32854-50-5 4,5-Secocholestane  *Cholestanes *Secosteroids. Steroids 1992 Nov;57(11):551-3
9,11-seco-3,6,11-trihydroxy-24-methylenecholest-7-en-9-one  143625-40-5   *Cholestenones *Secosteroids. Steroids 1992 Jul;57(7):344-7
9,11-seco-3,6,11-trihydroxycholest-7-en-9-one  143625-39-2   *Cholestenones *Secosteroids. Steroids 1992 Jul;57(7):344-7
physalin F  57423-71-9 16,24-Cyclo-13,14-secoergost-2-ene-18,26-dioic acid, 5,6:14,17:14,27-triepoxy-13,20,22-trihydroxy-1,15-dioxo-, gamma-lactone delta-lactone, (5beta,6beta,14alpha,16beta,22alpha,25S)  *Secosteroids. Anticancer Res 1992 May-Jun;12(3):837-44
14,15-secocholestane  131896-90-7   *Cholestanes *Secosteroids. Steroids 1990;55(6):263
13-ethyl-3-methoxy-8,14-secogona-1,3,5(10),9(11)-tetraene-14,17-dione  62298-52-6   *Gonanes *Secosteroids. Indian J Exp Biol 1989;27(8):742
3-hydroxy-14,15-secoestra-1,3,5(10)-trien-15-yn-17-one  117144-19-1   *Estrenes *Secosteroids Estradiol Dehydrogenases/antagonists & inhibitors. J Biol Chem 1988;263(24):11640
2,3-secocholestan-2,3-dioic acid  1178-00-3   *Cholestanes *Secosteroids. Biochim Biophys Acta 1988;940(1):85
3,4,7,12-tetrahydroxy-9,10-seco-1,3,5(10)-androstatriene-9,17-dione  113565-94-9   *Androstatrienes *Secosteroids. Steroids 1986;48(5-6):439
3,12-dihydroxy-9(10)-secoandrosta-1,3,5(10)-triene-9,17-dione  79683-94-6   *Androstatrienes *Secosteroids. Biochem J 1987;243(1):15
3,7-dihydroxy-5,9,17-trioxo-4(5),9(10)-disecoandrosta-1(10)2-dien-4-oic acid  108050-25-5   *Androstadienes *Secosteroids. Biochem J 1987;243(1):15
14,15-secoestra-1,3,5(10)-trien-15-yne-3,17-diol  104849-39-0   *Estrenes *Secosteroids Estradiol Dehydrogenases/antagonists & inhibitors. Biochemistry 1986;25(23):7295
methyl 3-hydroxy-9-oxo-9,10-seco-23,24-dinor-1,3,5(10)-cholatrienoate  103596-05-0   *Pregnatrienes *Secosteroids. Steroids 1985;46(2-3):789
4,5-secodihydrotestosterone  76760-84-4   Dihydrotestosterone/*analogs & derivatives Secosteroids. Exp Clin Endocrinol 1985;86(3):297
4-methyl-2,3-secocholestane-2,3-diol  95237-33-5   *Cholestanols *Secosteroids. Steroids 1984;43(3):305
2,3-secocholestane-2,3-diol  14124-56-2   *Cholestanols *Secosteroids. Steroids 1984;43(3):305
20-oxopregnacalciferol  86120-56-1 Ethanone, 1-(octahydro-4-((5-hydroxy-2-methylenecyclohexylidene)ethylidene)-7a-methyl-1H-inden-1-yl)-, (1S-(1alpha,3abeta,4E(1Z,5R*),7aalpha))  *Pregnatrienes *Secosteroids. J Steroid Biochem 1982;17(6):615
physalin B  23133-56-4   *Secosteroids. J Nat Prod 1981;44(5):579
4,5-allenic-3 beta-hydroxy-5,10-secosteroid  0   *Secosteroids. Biochem Biophys Res Commun 1981;101(2):495
withaphysalin C  57485-60-6 13,14-Secoergosta-2,5,24-trien-26-oic acid, 13,14:18,20-diepoxy-14,18,22-trihydroxy-1-oxo-, delta-lactone, (14alpha,22R)  *Secosteroids Ergosterol/*analogs & derivatives. J Chem Soc Perkin I 11:1244;1976
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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