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Dihydrotestosterone

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Definition: A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.     
Pharmacological Action Androgens
Examples Mesterolone 		Other names Stanolone; Androstanolone; 5 alpha-Dihydrotestosterone; 5 alpha Dihydrotestosterone; 5 alpha DHT; 17beta Hydroxy 5alpha Androstan 3 One; 17 beta Hydroxy 5 beta Androstan 3 One; Gelovit; Dihydroepitestosterone; Cuxson Brand of Androstanolone; Besins-Iscovesco Brand of Androstanolone; Berenguer Infale Brand of Androstanolone; Andractim; Anaprotin; 5-alpha-DHT; 5-alpha Dihydrotestosterone; 5 beta-Dihydrotestosterone; 17beta-Hydroxy-5alpha-Androstan-3-One; 17 beta-Hydroxy-5 beta-Androstan-3-One; beta-Hydroxy-5 beta-Androstan-3-One, 17
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RB 346  0   *Carbamates Dihydrotestosterone/*analogs & derivatives Androgen Antagonists. Biochem Pharmacol. 2011 Dec 1;82(11):1651-62.
7-alpha-fluoro-17 alpha-methyl-5-alpha-dihydrotestosterone  0   Dihydrotestosterone/*analogs & derivatives. Eur J Nucl Med Mol Imaging. 2008 Feb;35(2):379-85
7-fluoromethyldihydrotestosterone  0   Dihydrotestosterone/*analogs & derivatives Fluorine Radioisotopes. J Nucl Med 2008 Jun;49(6):987-94
16-fluorodihydrotestosterone  0   Dihydrotestosterone/*analogs & derivatives Fluorine Radioisotopes. J Nucl Med 2004 Nov;45(11):1966-71
18F-MDHT  0   Dihydrotestosterone/*analogs & derivatives. Nucl Med Biol 2001 Jan;28(1):85-90
17-hydroxy-7-fluoro-17-methylandrostan-3-one  0   Dihydrotestosterone/*analogs & derivatives Iodine Radioisotopes Ligands. J Med Chem 1999 Jun 3;42(11):2021-34
17-hydroxy-7-iodo-17-methylandrostan-3-one  0   Dihydrotestosterone/*analogs & derivatives Iodine Radioisotopes Ligands. J Med Chem 1999 Jun 3;42(11):2021-34
L 751788  0   *Azasteroids Dihydrotestosterone/*analogs & derivatives. J Chromatogr B Biomed Sci Appl 1998 Aug 25;713(2):371-8
11-fluoro-19-nor-dihydro-testosterone  111984-13-5   Dihydrotestosterone/*analogs & derivatives Fluorine Radioisotopes Nandrolone. J Med Chem 1995 Mar 3;38(5):816-25
11-fluoro-dihydro-testosterone  111984-12-4   Dihydrotestosterone/*analogs & derivatives Fluorine Radioisotopes Testosterone Congeners. J Med Chem 1995 Mar 3;38(5):816-25
7-iodo-17-hydroxy-3-androstanone  0   Dihydrotestosterone/*analogs & derivatives Radioligand Assay. J Med Chem 1994 Apr 15;37(8):1224-30
17-(2-iodoethynyl)androsta-4,6-dien-17-ol-3-one  145430-54-2   Dihydrotestosterone/*analogs & derivatives Ligands. Steroids 1992 Nov;57(11):569-76
17-(2-iodoethenyl)androsta-4,6-dien-17-ol-3-one  145624-22-2   Dihydrotestosterone/*analogs & derivatives Ligands. Steroids 1992 Nov;57(11):569-76
2-chloroethylnitrosocarbamoylalanine 17-dihydrotestosterone ester  89083-93-2   *Nitrogen Mustard Compounds Dihydrotestosterone/*analogs & derivatives. Br J Cancer Res 1990;62(1):42
17-(2-iodovinyl)dihydrotestosterone  129163-98-0   Dihydrotestosterone/*analogs & derivatives. J Steroid Biochem 1990 Jun;36(1-2):125-32
testiphenon  104730-58-7   *Nitrogen Mustard Compounds Drug Combinations Dihydrotestosterone/*analogs & derivatives. Vopr Onkol 1988;34(11):1363
5-dihydrotestosterone 3,17-bromoacetate  121520-97-6   Dihydrotestosterone/*analogs & derivatives. Ann N Y Acad Sci 1988;538:10
17-hydroxyandrostan-3-one 17-sulfate  20448-84-4   Dihydrotestosterone/*analogs & derivatives. J Steroid Biochem 1988 Jun;29(6):677-84
androstan-3,17-diol-11-one  77983-84-7   Dihydrotestosterone/*analogs & derivatives. Gen Comp Endocrinol 1988;70(1):91
17-epoxypropyldihydrotestosterone thiopropyl-sepharose  0   Sepharose/*analogs & derivatives Dihydrotestosterone/*analogs & derivatives. J Steroid Biochem 1986;24(6):1111
dihydrotestosterone heptanoate  33776-88-4   Dihydrotestosterone/*analogs & derivatives. J Pediatr 1986;109(1):144
4,5-secodihydrotestosterone  76760-84-4   Dihydrotestosterone/*analogs & derivatives Secosteroids. Exp Clin Endocrinol 1985;86(3):297
17-N,N-diisopropylcarbamoyl-4-azaandrostan-3-one  89631-79-8   *Azasteroids Dihydrotestosterone/*analogs & derivatives 3-Oxo-5-alpha-Steroid 4-Dehydrogenase/antagonists & inhibitors. Endocrinology 1986 Jan;118(1):132-7
17-ketotrilostane  94152-62-2   Dihydrotestosterone/*analogs & derivatives. J Steroid Biochem 1984;21(5):601
stanolone benzoate  1057-07-4   Dihydrotestosterone/*analogs & derivatives. Biol Reprod 1983;29(4):970
androstan-3-one  1224-95-9   Dihydrotestosterone/*analogs & derivatives. Biol Psychol 1983;16(1-2):85
dihydrotestosterone glucuronide  42037-24-1   Dihydrotestosterone/*analogs & derivatives. J Clin Endocrinol Metab 1978;47(6):1282
18-hydroxy-18-methyl-16,17-methylene-D-homoandrostane-3-one  83606-93-3 3'H-Cyclopropa(16,17)-D-homoandrost-16-en-3-one, 16,17-dihydro-17a-hydroxy-17a-methyl-, (5alpha,16beta,17beta,17abeta)  Dihydrotestosterone/*analogs & derivatives. Int J Androl 1982 Aug;5(4):413-24
dihydrotestosterone-17-N-bis(2-chloroethyl)carbamate  53033-00-4   *Nitrogen Mustard Compounds Dihydrotestosterone/*analogs & derivatives. J Steroid Biochem 1982;17(1):23
16-iodostanolone  82810-68-2 Androstan-3-one, 17-hydroxy-16-iodo-, (5alpha,16alpha,17beta)  Dihydrotestosterone/*analogs & derivatives. J Steroid Biochem 1982;16(5):621
4,17-dimethyltrilostane  71507-79-4   Dihydrotestosterone/*analogs & derivatives. Contraception 1981;24(3):289
17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one  73671-86-0 4-Azaandrostane-17-carboxamide, N,N-diethyl-4-methyl-3-oxo-, (5alpha,17beta)  *Azasteroids Dihydrotestosterone/*analogs & derivatives.
Pharma Action Androgen Antagonists ; 5-alpha Reductase Inhibitors 		J Biol Chem 1981 Aug;256(15):7998-8005
dihydrotestosterone propionate  855-22-1   Dihydrotestosterone/*analogs & derivatives. Physiol Behav 1981;26(3):473
dihydrotestosterone 17-bromoacetate  66656-21-1 (5 alpha,17 beta)-17-((bromoacetyl)oxy)androstan-3-one  Dihydrotestosterone/*analogs & derivatives. Biochemistry 1980;19(5):978
1,2-seco-A-bis(norandrostan-17-ol)acetate  40401-16-9 1H-Benz(e)inden-3-ol, dodecahydro-3a,6,6,7-tetramethyl-, acetate, (3S-(3alpha,3aalpha,5abeta,7alpha,9aalpha,9bbeta))  *Androstanols Dihydrotestosterone. Steroids 1979;34(5):589-95
7-hemisuccinamido-5-dihydrotestosterone  0   Dihydrotestosterone/*analogs & derivatives Haptens. Steroids 34(1):15;1979
7-(O-carboxymethyl)oximino-5-dihydrotestosterone  0   Dihydrotestosterone/*analogs & derivatives Haptens. Steroids 34(1):15;1979
3-(O-carboxymethyl)oximino-5-dihydrotestosterone  0   Dihydrotestosterone/*analogs & derivatives Haptens. Steroids 34(1):15;1979
nitrostanolone  21957-21-1   *Dihydrotestosterone. Agressologie 19(1):39;1978; Agressologie 19(2):123;1978
2-bromo-5-dihydrotestosterone  29041-91-6   Dihydrotestosterone/*analogs & derivatives. Eur J Nucl Med 2(3):155;1977
demalon  2881-21-2 1 alpha,17 alpha-dimethyl-5-androstan-17-ol-3-one  Dihydrotestosterone/*analogs & derivatives. Endokrinol 69(1):115;1977
3-hydroxyandrostan-16-one  571-51-7   *Dihydrotestosterone Isomerism. J Chem Soc (Perkin Trans) 1976;12:1350-1
17-hydroxyandrostan-19-ol-3-one  2026-82-6 5 alpha-androstane-17 beta,19-diol-3-one  Dihydrotestosterone/*analogs & derivatives. J Endocrinol 68(1):173;1976
2,17-dimethyldihydrotestosterone  3381-88-2 17 beta-hydroxy-2 alpha,17-dimethyl-5 alpha-androstan-3-one  Dihydrotestosterone/*analogs & derivatives. Steroids 26(5):663;1975
trilostane  13647-35-3   Dihydrotestosterone/*analogs & derivatives Oxidative Phosphorylation Coupling Factors 3-Hydroxysteroid Dehydrogenases/antagonists & inhibitors.
Pharma Action Abortifacient Agents, Steroidal ; Antineoplastic Agents ; Enzyme Inhibitors 		Endocrinology 103(4):1411;1978; Endocrinology 97(1):136;1975; Fertil Steril 1979;32(4):464; J Endocrinol 76:293;1978; Steroids 32(2):257;1978MODRASTANE
mestanolone  521-11-9   Dihydrotestosterone/*analogs & derivatives.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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