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Pregnatrienes

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Definition: Pregnane derivatives containing three double bonds in the ring structures.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
9-bromide-11-hydroxypregna-1, 4, 16-trien-3, 20-dione  0   *Pregnatrienes. Steroids. 2009 Feb;74(2):229-32
17-hydroxy-16-methyl-1,4,6-pregnatriene-3,20-dione  0   *Pregnatrienes. Andrologia 2009 Feb;41(1):29-34
U 87999  0   *Pregnatrienes. Int J Clin Pharmacol Ther 1997 Jan;35(1):28-32
RU 1968  0   *Pregnatrienes. J Steroid Biochem Mol Biol 1996 Sep;59(1):49-54
9,21-dichloro-20-((2'-furanylcarbonyl)oxy)-11-hydroxy-16,17-dimethyl-18-norpregna-1,4,13,20-tetraen-3-one  0   *Pregnatrienes. Steriods 1995 Sep;60(9):612-4
U 89678  0   *Pregnatrienes. J Pharmacol Exp Ther 1994 Apr;269(1):145-50
16-methylene-17-hydroxypregna-1,4,9(11)-triene-3,20-dione  19683-23-9   *Pregnatrienes. Steroids 1993 Sep;58(9):396-9
U 74389F  111668-89-4   *Pregnatrienes.
Pharma Action Antioxidants ; Immunosuppressive Agents ; Radiation-Protective Agents ; Neuroprotective Agents 		Cancer Lett 1992 May 30;64(1):61-6
stizophyllin  109237-00-5   *Pregnatrienes. Chem Biol Interact 1991;80(1):43
6-methyl-3,20-dioxo-1,4,9(11)-pregnatrien-17-acetate  130145-14-1   *Pregnatrienes. Acta Crystallogr C 1990;46:1498
21-(4(3,6-di-N-diethylamine-2-pyridinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)-triene-3,20-dione  111640-85-8   *Pregnatrienes. J Chromatogr 1988;424(2):285
U 74500A  110101-65-0 Pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(3,6-bis(diethylamino)-2-pyridinyl)-1-piperazinyl)-16-methyl-, hydrochloride, (16alpha)  *Pregnatrienes.
Pharma Action Anti-Ulcer Agents ; Antioxidants ; Immunosuppressive Agents 		J Biol Chem 1987;262(22):10438
tirilazad  110101-67-2 Pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methyl-, (16alpha)-, monomethanesulfonate  *Pregnatrienes.
Pharma Action Antioxidants ; Neuroprotective Agents 		J Biol Chem 1987;262(22):10438
17-hydroxy-4,6,8(14)-pregnatriene-3,20-dione  14147-97-8   *Pregnatrienes. Biochim Biophys Acta 1987;923(1):83
methyl 3-hydroxy-9-oxo-9,10-seco-23,24-dinor-1,3,5(10)-cholatrienoate  103596-05-0   *Pregnatrienes *Secosteroids. Steroids 1985;46(2-3):789
deacylcortivazol 21-mesylate  50630-90-5 2'H-Pregna-2,4,6-trieno(3,2-c)pyrazol-20-one, 11,17-dihydroxy-6,16-dimethyl-21-((methylsulfonyl)oxy)-2'-phenyl-, (11beta,16alpha)  *Pregnatrienes. Endocrinology 1984;114(6):2252
20-oxopregnacalciferol  86120-56-1 Ethanone, 1-(octahydro-4-((5-hydroxy-2-methylenecyclohexylidene)ethylidene)-7a-methyl-1H-inden-1-yl)-, (1S-(1alpha,3abeta,4E(1Z,5R*),7aalpha))  *Pregnatrienes *Secosteroids. J Steroid Biochem 1982;17(6):615
deacylcortivazol  4906-84-7   *Pregnatrienes. J Steroid Biochem 1981;14(3):273
DU 41274  67580-43-2 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 17-ethoxy-6-fluoro-1,2-dihydro-, (1alpha,2alpha,9beta,10alpha)  *Pregnatrienes. Clin Toxicol 18:291;1977-W3:EX89(417);1976
neridienone A  53823-05-5 12-beta-hydroxypregna-4,6,16-triene-3,20-dione  *Pregnatrienes. Chem Pharm Bull (Tokyo) 22(7):1680;1974
cortivazol  1110-40-3 11 beta,17 alpha,21- trihydroxy-6,16 alpha-dimethyl-2'-phenylpregna- 2,4,6-trieno(3,2-c)pyrazol-20-one 21-acetate  *Pregnatrienes.
Pharma Action Anti-Inflammatory Agents 		Boll Chim Farm 114(5):279;1975; Rev Clin Esp 129(5):491;1973

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