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Radiation-Protective Agents

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Definition: Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other, e.g. military, purposes.  SUNSCREENING AGENTS is also available; use RADIATION PROTECTION for shielding from diagnostic x-rays; note entry term RADIATION-PROTECTIVE EFFECT: use only for the radiation protective effect of a chemical substance   
Examples Sunscreening Agents 		Other names Radioprotective Agents; Radiation Protective Effects; Radiation Protective Effect; Radiation Protective Drugs; Protective Agents, Radiation; Protectants, Radiation; Effects, Radiation-Protective; Effect, Radiation-Protective; Drugs, Radioprotective; Drugs, Radiation-Protective; Agents, Radioprotective; Agents, Radiation Protective; Radioprotective Drugs; Radiation-Protective Effects; Radiation-Protective Effect; Radiation-Protective Drugs; Radiation Protective Agents; Radiation Protectants; Agents, Radiation-Protective
Substances having this pharmacologic action: cepharanthine; HOE 33342; WR 1065; zinc thionein; hydroquinone; 4-aminopropiophenone; Ribomunyl; gusperimus; 5-(2-formyl-3-hydroxyphenoxy)pentanoic acid; nitrox; irsogladine; tetrachlorodecaoxide; S-ethyl glutathione; triethylenediamine; 6-methyluracil; homocysteine thiolactone; alginic acid; tempol; tributyl phosphate; krestin; 6-methyl-2-ethyl-3-hydroxypyridine; benzobarbital; Deuterium Oxide; beta-Aminoethyl Isothiourea; Buthionine Sulfoximine; Pentoxifylline; Cystamine; Amifostine; Cystaphos; Cysteamine; Adeturon; sulfolane; creatinine sulfate, serotonin drug combination; lycopene; Actovegin; flt3 ligand protein; U 74389F; ammonium trichloro(dioxoethylene-O,O'-)tellurate; goralatide; S-2-(3-methylaminopropylamino)ethylphosphorothioic acid
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MCF201-89  0   *Thiazines Radiation-Protective Agents. Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):860-8
BEB55 compound  0   *Imidazoles *Indoles Radiation-Protective Agents. Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):860-8
buriti oil  0   *Carotenoids *Plant Oils Radiation-Protective Agents. Food Chem Toxicol. 2010 Jan;48(1):70-5
MP-33  0   Proteins Radiation-Protective Agents. Radiats Biol Radioecol 1999 Mar-Jun;39(2-3):277-81
MDI radiation protective agent  0   *Plant Extracts Radiation-Protective Agents. Radiats Biol Radioecol 1994 Jan-Feb;34(1):143-7
ivastimul  0   *Chlorella *Plant Extracts Radiation-Protective Agents. Radiobiologiia 1989;29(5):652
epigallocatechin gallate  989-51-5   Catechin/*analogs & derivatives Protease Inhibitors Radiation-Protective Agents Urokinase-Type Plasminogen Activator/antagonists & inhibitors.
Pharma Action Antioxidants ; Antimutagenic Agents ; Anticarcinogenic Agents ; Neuroprotective Agents 		Mutat Res 1985;150(1-2):127
pyrimetine  59473-13-1   Organic Chemicals Radiation-Protective Agents. Acta Physiol Pharmacol Bulg 4(3):21;1978
chlorophyllin  15611-43-5   *Chlorophyllides Anti-Infective Agents, Local Radiation-Protective Agents.
Pharma Action Antimutagenic Agents 		Bioenergetics 4(5):469;1973; Bull Soc Ophthalmol Fr 1979;79(3):203; J Am Geriatr Soc 1980;28(1):46; J Fran Ophthal 1(8/():547;1978; Photochem Photobiol 22(6):265;1975
troxerutin  7085-55-4 2-(3,4-bis(2-hydroxyethoxy)phenyl)-3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl)oxy)-5-hydroxy-7-(2-hydroxy ethoxy)-4H-1-benzopyran-4-one  Hydroxyethylrutoside/*analogs & derivatives Radiation-Protective Agents Vasoconstrictor Agents.
Pharma Action Anticoagulants 		Arzneim Forsch 27(7):1499;1977; Arzneim Forsch 28(5):982;1978; Sem Hop Ther 53(7-8):363;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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