encyclopedia of medical concepts
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Amifostine
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Definition
: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
D25-26 qualif
Pharmacological Action
Radiation-Protective Agents
Other names
Gammaphos; Ethiofos; YM08310; YM 08310; WR2721; WR 2721; Schering Plough Brand of Amifostine; Salt, Amifostine Disodium; NSC296961; NSC 296961; Monohydrochloride, Amifostine; Monohydrate, Amifostine; Disodium Salt, Amifostine; Amifostine Schering-
Plough Brand; Amifostine Lilly Brand; Amifostine Essex Brand; Amifostine Alza Brand; Acid, Aminopropylaminoethylthiophosphoric; YM-
08310; WR-
2721
Drugs
*
:
AMIFOSTINE
;
ETHYOL
Substance
CAS Registry & name
Categories
Source
Drugs
*
S-
2 (4-
aminobutylamino)ethylphenylsulfide
0
Amifostine/*analogs & derivatives.
Toxicol Appl Pharmacol 2001 Oct 1;176(1):24-33
S-
2 (2-
aminoethylamino)ethylphenylsulfide
0
Amifostine/*analogs & derivatives.
Toxicol Appl Pharmacol 2001 Oct 1;176(1):24-33
S-
2 (3-
aminopropylamino)ethylphenylsulfide
0
Amifostine/*analogs & derivatives.
Toxicol Appl Pharmacol 2001 Oct 1;176(1):24-33
GAP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Deoxycytidine/analogs & derivatives
Amifostine.
Anticancer Drugs 1998 Jul;9(6):511-4
ACV protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Amifostine
Vinblastine.
J Clin Oncol 1996 Jun;14(6):1913-21
S-
2-
(3-
methylaminopropylamino)ethylphosphorothioic acid
20751-90-0
Amifostine/*analogs & derivatives.
Pharma Action
Radiation-Protective Agents
Radiat Res 1986;106(3):366
WR 77913
58319-25-8
Amifostine/*analogs & derivatives.
Pharma Action
Radiation-Sensitizing Agents
Int J Radiat Oncol Biol Phys 1982;8(3-4):553