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Cystamine

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Definition: A radiation-protective agent that interferes with sulfhydryl enzymes. It may also protect against carbon tetrachloride liver damage.  do not confuse with CYSTEAMINE nor Cystamin (a urinary antiseptic)   
Pharmacological Action Enzyme Inhibitors; Radiation-Protective Agents; Sulfhydryl Reagents
Other names Diaminodiethyldisulfide; Decarboxycystine; Cystineamine; Sulfate, Cystamine; Hydrochloride, Cystamine; Hydrobromide, Cystamine; Disulfide, Cysteinamine; Dihydrochloride, Cystamine; Dihydrobromide, Cystamine; Diacetate, Cystamine; Calcium Salt, Cystamine; 2,2' Dithiobisethanamine; Cysteinamine Disulfide; Cystamine Sulfate (1:1); Cystamine Sulfate; Cystamine Hydrochloride; Cystamine Hydrobromide; Cystamine Dihydrochloride; Cystinamin; Cystamine Dihydrobromide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
fluorescein-cystamine-methyl red  0   *Fluoresceins Cystamine/*analogs & derivatives. Biochem Biophys Res Commun 2005 May 27;331(1):351-6
N,N'-dilinoleylcystamine  0   Cystamine/*analogs & derivatives. Br J Dermatol 2004 Jan;150(1):39-46
cystamine thiolsulfonate  0   *Sulfones Cystamine/*analogs & derivatives. Amino Acids 1998;15(4):363-72
N-propionyl-4-S-cysteaminylphenol  0   *Phenols Cystamine/*analogs & derivatives. Biochem Pharmacol 1998 Jun 15;55(12):2023-9
cystamine bislactamide  0   *Lactates Cystamine/*analogs & derivatives Allergens Cosmetics. Lancet 1998 Jun 20;351(9119):1861-2
N,N'-bis(glycyl)cystamine  0   Cystamine/*analogs & derivatives. Bioconjug Chem 1998 May-Jun;9(3):309-15
N,N'-bis(N-dodecyl-N,N-dimethylglycine)cystamine dihydrochloride  0   Cystamine/*analogs & derivatives Glycine/*analogs & derivatives. J Appl Bacteriol 1996 Aug;81(2):212-6
bis(2-(2-hexenoylamino)ethyl) disulfide  112614-14-9   *Alkenes Cystamine/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1989;37(7):1946
pyrextramine  92588-09-5   Cystamine/*analogs & derivatives. Eur J Pharmacol 1984;103(1-2):181
N,N-bis(alpha-iodoacetyl)-2,2'-dithiobis(ethylamine)  80214-56-8 Acetamide, N,N'-(dithiodi-2,1-ethanediyl)bis(2-iodo)  Cystamine/*analogs & derivatives. Anal Biochem 1981;117(1):76
benextramine  69790-18-7   Cystamine/*analogs & derivatives.
Pharma Action Adrenergic alpha-Antagonists
Can J Physiol Pharmacol 1980;58(8):984
homocystamine  463-22-9 1-propanamine, 3,3'-dithiobis  Cystamine/*analogs & derivatives. Ital J Biochem 1980;29(4):251
N,N'-bisacrylylcystamine  60984-57-8 2-Propenamide, N,N'-(dithiodi-2,1-ethanediyl)bis  Cystamine/*analogs & derivatives. Anal Biochem 1980;105(1):192
N-acetyl-N'-(4-glyoxylylbenzoyl)cystamine  73097-03-7 Benzamide, N-(2-((2-(acetylamino)ethyl)dithio)ethyl)-4-(oxoacetyl)  Cystamine/*analogs & derivatives. Eur J Biochem 1980;103(2):365
N,N-tetramethylcystamine  1072-11-3   Cystamine/*analogs & derivatives. Radiobiologiia 17(4):586;1977
DNCO  64273-10-5 Ethanesulfonothioic acid, 2-((4-azido-2-nitrophenyl)amino)-, S-(2-((4-azido-2-nitrophenyl)amino)ethyl) ester  Cystamine/*analogs & derivatives. J Biol Chem 252(15):5514;1977
selenohomocystamine  51541-77-6 3,3'-diselenobis-1-propanamine  *Organoselenium Compounds Cystamine/*analogs & derivatives. Boll Soc Ital Biol Sper 52(12):917;1976
selenocystamine  2697-61-2 2,2'-diselenobisethanamine  *Organoselenium Compounds Cystamine/*analogs & derivatives. Ital J Biochem 25(5):382;1976
isothienylic acid  0   *Cystamine. Vopr Med Khim 19(1):22;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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