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Casein Kinases

More information in Books or onNLM PubMed
Definition: A group of protein-serine-threonine kinases that was originally identified as being responsible for the PHOSPHORYLATION of CASEINS. They are ubiquitous enzymes that have a preference for acidic proteins. Casein kinases play a role in SIGNAL TRANSDUCTION by phosphorylating a variety of regulatory cytoplasmic and regulatory nuclear proteins.  general or unspecified; prefer specifics   
Examples Casein Kinase I; Casein Kinase II 		Other names Kinases, Casein; Kinase, Casein; Casein Kinase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TNF-IL1-activated protein kinase  EC 2.7.1.37   *Casein Kinases. Cytokine 1997 Jul;9(7):471-9
protein kinase CK42  EC 2.7.1.37   *DNA-Binding Proteins *Casein Kinases. Cell Mol Biol Res 1994;40(5-6):463-72

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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