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Proto-Oncogene Proteins c-cbl

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Definition: Proto-oncogene proteins that negatively regulate RECEPTOR PROTEIN-TYROSINE KINASE signaling. It is a UBIQUITIN-PROTEIN LIGASE and the cellular homologue of ONCOGENE PROTEIN V-CBL.      Other names cbl Proto Oncogene Protein; c-cbl, Proto-Oncogene Proteins; c-cbl, Proto-Oncogene Protein; c cbl Proto Oncogene Protein; Proto-Oncogene Protein, cbl; Proto-Oncogene Protein, c-cbl; Proto Oncogene Proteins c cbl; Proto Oncogene Protein c cbl; Proteins c-cbl, Proto-Oncogene; c-cbl Proto-Oncogene Protein; Proto-Oncogene Protein c-cbl; CBL E3 Ubiquitin Protein Ligase; cbl Proto-Oncogene Protein; c-cbl Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Cbl protein, mouse  EC 6.3.2.-   *Proto-Oncogene Proteins c-cbl.
Cblb protein, rat  EC 6.3.2.19   *Adaptor Proteins, Signal Transducing *Proto-Oncogene Proteins c-cbl.
CBLB protein, human  EC 6.3.2.19   *Adaptor Proteins, Signal Transducing *Proto-Oncogene Proteins c-cbl.
CBLL1 protein, human  EC 6.3.2.19   *Ubiquitin-Protein Ligases Cadherins Proto-Oncogene Proteins c-cbl.
Cblc protein, mouse  EC 6.3.2.-   *Proto-Oncogene Proteins c-cbl Zinc Fingers. Biochem Biophys Res Commun 2001 Jan 12;280(1):
CBLC protein, human  EC 6.3.2.-   *Proto-Oncogene Proteins c-cbl. Oncogene 1999 Jun 3;18(22):3365-75
Cblb protein, mouse  EC 6.3.2.19   *Adaptor Proteins, Signal Transducing *Proto-Oncogene Proteins c-cbl. Oncogene 1995 Jun 15;10(12):2367-77
Cbl protein, Drosophila  EC 6.3.2.-   *Drosophila Proteins *Proto-Oncogene Proteins c-cbl Signal Transduction. Oncogene 1997 Jun 5;14(22):2709-19
CBL protein, human  EC 6.3.2.-   *Proto-Oncogene Proteins c-cbl. Genomics 1990;8(3):447

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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