encyclopedia of medical concepts
ψ 
ψ 
ψ 

Adaptor Proteins, Signal Transducing

More information in Books or onNLM PubMed
Definition: A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes     
Examples A Kinase Anchor Proteins; CARD Signaling Adaptor Proteins; Caveolin 1; Caveolin 2; Cortactin; Crk-Associated Substrate Protein; Death Domain Receptor Signaling Adaptor Proteins; GRB2 Adaptor Protein; GRB7 Adaptor Protein; GRB10 Adaptor Protein; Insulin Receptor Substrate Proteins; Interferon Regulatory Factors; Interferon-Stimulated Gene Factor 3; Mediator Complex; Myeloid Differentiation Factor 88; Nod Signaling Adaptor Proteins; Nuclear Receptor Coactivators; Paxillin; PII Nitrogen Regulatory Proteins; Protein Inhibitors of Activated STAT; 14-3-3 Proteins; Proto-Oncogene Proteins c-crk; Proto-Oncogene Proteins c-vav; Retinoblastoma Binding Proteins; Shc Signaling Adaptor Proteins; Smad Proteins; STAT Transcription Factors; Suppressor of Cytokine Signaling Proteins; Syntenins; Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Other names Signal Transducing Adaptor Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
WIF1 protein, zebrafish  0   *Repressor Proteins *Zebrafish Proteins *Adaptor Proteins, Signal Transducing. Biochim Biophys Acta. 2012 Feb;1823(2):236-44
NUP98-PSIP1 fusion protein, human  0   *Oncogene Proteins, Fusion *Nuclear Pore Complex Proteins *Adaptor Proteins, Signal Transducing Transcription Factors. Leuk Res. 2011 Jun;35(6):e75-6.
late endosome-lysosome membrane adaptor p18, mouse  0   *Adaptor Proteins, Signal Transducing. Biochem Biophys Res Commun. 2012 Jan 27;417(4):1151-7.
EHD protein-binding protein 1, Drosophila  0   *Drosophila Proteins *Adaptor Proteins, Signal Transducing. J Cell Biol. 2012 Jan 9;196(1):65-83.
PRAS40 protein, Drosophila  0   *Drosophila Proteins *Adaptor Proteins, Signal Transducing. Dev Cell. 2012 Jan 17;22(1):172-82
Dlgh1 protein, human  0   *Adaptor Proteins, Signal Transducing. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1625-30
Abl interactor 1 protein, human  0   *Adaptor Proteins, Signal Transducing. Biochem J. 2012 Feb 1;441(3):889-99
FAM123A protein, human  0   *Tumor Suppressor Proteins *Adaptor Proteins, Signal Transducing. J Biol Chem. 2012 Jan 13;287(3):1734-41
SCIMP protein, human  0   *Membrane Proteins *Adaptor Proteins, Signal Transducing. Mol Cell Biol. 2011 Nov;31(22):4550-62.
complexin 3 protein, human  0   *Adaptor Proteins, Signal Transducing. Nat Struct Mol Biol 2011 Aug;18(8):941-6
liprin-alpha1 protein, rat  0   *Adaptor Proteins, Signal Transducing. Synapse. 2011 Aug;65(8):742-50
arouser protein, Drosophila  0   *Arabidopsis Proteins *Adaptor Proteins, Signal Transducing. Neuron 2011 Jun 9;70(5):979-90
AFAP1L1 protein, human  0   *Microfilament Proteins *Adaptor Proteins, Signal Transducing. Eur J Cell Biol 2011 May;90(5):376-89
KCASH2 protein, human  0   *Adaptor Proteins, Signal Transducing. Neoplasia 2011 Apr;13(4):374-85
KCASH3 protein, human  0   *Adaptor Proteins, Signal Transducing. Neoplasia 2011 Apr;13(4):374-85
ECSIT protein, mouse  0   *Adaptor Proteins, Signal Transducing. Nature. 2011 Apr 28;472(7344):476-80
Prickle1a protein, zebrafish  0   *Zebrafish Proteins *Adaptor Proteins, Signal Transducing *LIM Domain Proteins.
caskin protein, Drosophila  0   *Nerve Tissue Proteins *Drosophila Proteins *Adaptor Proteins, Signal Transducing. J Neurosci. 2011 Mar 23;31(12):4421-33
Odin protein, human  0   *Adaptor Proteins, Signal Transducing. Oncogene 2002 Nov 14;21(52):8029-36
Par6B protein, human  0   *Adaptor Proteins, Signal Transducing. Mol Biol Cell 2010 Sep;21(17):2996-3006
CHB-3 protein, C elegans  0   *Caenorhabditis elegans Proteins *Adaptor Proteins, Signal Transducing Ankyrin Repeat. PLoS Genet 2010;6(11):e1001211
Spg21 protein, mouse  0   *Adaptor Proteins, Signal Transducing. Neurogenetics 2010 Oct;11(4):369-78
Abi1 protein, rat  0   *Adaptor Proteins, Signal Transducing. Mol Psychiatry 2010 Oct;15(10):976-86
mapk8ip3 protein, rat  0   *Nerve Tissue Proteins *Adaptor Proteins, Signal Transducing. Alcohol. 2010 Sep;44(6):477-85
COMMD7 protein, human  0   *Adaptor Proteins, Signal Transducing. Hepatogastroenterology. 2010 Jul-Aug;57(101):919-25
MzrA protein, E coli  0   *Escherichia coli Proteins *Adaptor Proteins, Signal Transducing. J Bacteriol 2010 Dec;192(23):6271-8
p37 protein, human  0   *Adaptor Proteins, Signal Transducing. Biochem Biophys Res Commun 2010 Nov 5;402(1):37-41
Appl1 protein, Xenopus  0   *Xenopus Proteins *Adaptor Proteins, Signal Transducing. Dev Dyn 2010 Aug;239(8):2198-207
TIRAP protein, zebrafish  0   *Zebrafish Proteins *Adaptor Proteins, Signal Transducing. J Immunol 2010 Sep 15;185(6):3391-400
AMBRA1 protein, human  0   *Adaptor Proteins, Signal Transducing. J Cell Biol 2010 Oct 4;191(1):155-68
DOK6 protein, mouse  0   *Adaptor Proteins, Signal Transducing Phosphoproteins. BMC Biol 2010;8:96
fibroblast receptor substrate 2, rat  0   *Adaptor Proteins, Signal Transducing. J Neurosci Res 2010 Jul;88(9):1882-9
Dok-7 protein, zebrafish  0   *Zebrafish Proteins *Adaptor Proteins, Signal Transducing. Hum Mol Genet 2010 May 1;19(9):1726-40
SH2D4B protein, human  0   *Adaptor Proteins, Signal Transducing. Immunol Rev 2009 Nov;232(1):240-54
COMMD1 protein, rat  0   *Adaptor Proteins, Signal Transducing. Am J Physiol Renal Physiol 2010 Jun;298(6):F1445-56
Dab1 protein, zebrafish  0   *Zebrafish Proteins *Adaptor Proteins, Signal Transducing. Comp Biochem Physiol B Biochem Mol Biol. 2010 Mar;155(3):217-29
ACBD5 protein, human  0   *Membrane Proteins *Adaptor Proteins, Signal Transducing. Thyroid. 2010 Jan;20(1):43-9
Bcl9 protein, Xenopus  0   *Xenopus Proteins *Adaptor Proteins, Signal Transducing. Dev Dyn 2010 Jan;239(1):271-83
ARP protein, Xenopus  0   *Xenopus Proteins *Adaptor Proteins, Signal Transducing. Dev Dyn 2010 Jan;239(1):261-70
Tks4 protein, human  0   *Adaptor Proteins, Signal Transducing. Am J Hum Genet 2010 Feb 12;86(2):254-61
Pik3ap1 protein, rat  0   *Adaptor Proteins, Signal Transducing.
KLHL18 protein, Drosophila  0   *Drosophila Proteins *Adaptor Proteins, Signal Transducing. Genes Cells 2009 Aug;14(8):965-73
2810453I06Rik protein, mouse  0   *Nuclear Proteins *Adaptor Proteins, Signal Transducing. Int J Urol. 2009 Jul;16(7):639-46
ARL6IP protein, rat  0   *Membrane Proteins *Adaptor Proteins, Signal Transducing. Bioorg Med Chem. 2009 Sep 1;17(17):6188-95
Lnk protein, Drosophila  0   *Drosophila Proteins *Adaptor Proteins, Signal Transducing. PLoS Genet 2009 Aug;5(8):e1000596
Elmo2 protein, mouse  0   *Cytoskeletal Proteins *Adaptor Proteins, Signal Transducing. Cell 2001 Oct 5;107(1):27-41
rabconnectin-3 protein, Drosophila  0   *Drosophila Proteins *Adaptor Proteins, Signal Transducing. Dev Cell. 2009 Sep;17(3); 387-402
Epg-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Adaptor Proteins, Signal Transducing. Autophagy 2009 Jul;5(5):608-15
UBXN-5 protein, C elegans  0   *Caenorhabditis elegans Proteins *Adaptor Proteins, Signal Transducing. Biochem Biophys Res Commun 2009 Sep 4;386(4):575-81
Morg1 protein, human  0   *Adaptor Proteins, Signal Transducing. Neurosci Lett 2009 May 8;455(1):46-50
Asb2 protein, mouse  0   *Adaptor Proteins, Signal Transducing. Cell Death Differ 2009 Jun;16(6):921-32
SPIN90 protein, mouse  0   *Nerve Tissue Proteins *Adaptor Proteins, Signal Transducing. J Neurochem 2009 May;109(4):1106-17
ABI3 protein, human  0   *Adaptor Proteins, Signal Transducing. Biochim Biophys Acta 2000 Sep 7;1493(1-2):237-41
ZFYVE28 protein, human  0   *Membrane Proteins *Adaptor Proteins, Signal Transducing Zinc Fingers. Dev Cell 2009 May;16(5):687-98
TTP protein, mouse  0   *Adaptor Proteins, Signal Transducing. J Biochem. 2009 Mar;145(3):403-9
Rcn2 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Adaptor Proteins, Signal Transducing. Mol Cell Biol 2009 May;29(10):2777-93
BABAM1 protein, human  0   *Adaptor Proteins, Signal Transducing DNA Repair. Genes Dev 2009 Mar 15;23(6):719-28
lipid raft adaptor p18 protein, rat  0   *Adaptor Proteins, Signal Transducing. EMBO J 2009 Mar 4;28(5):477-89
lipid raft adaptor p18 protein, mouse  0   *Adaptor Proteins, Signal Transducing. EMBO J 2009 Mar 4;28(5):477-89
Arl6ip protein, zebrafish  0   *Zebrafish Proteins *Adaptor Proteins, Signal Transducing. Dev Dyn 2009 Jan;238(1):232-40
more...

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify.
We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy