encyclopedia of medical concepts
ψ 
ψ 
ψ 

Protein Inhibitors of Activated STAT

More information in Books or onNLM PubMed
Definition: A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.      Other names PIAS4 Protein Inhibitor of Activated STAT; PIAS3 Protein Inhibitor of Activated STAT; PIAS2 Protein Inhibitor of Activated STAT; PIAS1 Protein; PIAS Proteins; PIAS1 Protein Inhibitor of Activated STAT
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ZMIZ2 protein, human  0   *Protein Inhibitors of Activated STAT. Mol Endocrinol. 2005 Dec;19(12):2915-9
PIAS2 protein, human  0   *Protein Inhibitors of Activated STAT.
PIASy protein, Xenopus  0   *Repressor Proteins *Xenopus Proteins *Protein Inhibitors of Activated STAT. Development 2004 Nov;131(22):5613-26
Pias1 protein, mouse  0   *Protein Inhibitors of Activated STAT.
PIAS4 protein, human  0   *Protein Inhibitors of Activated STAT Nuclear Proteins Signal Transduction.
Miz1 protein, mouse  0   *Nuclear Proteins *Protein Inhibitors of Activated STAT.
PIAS3 protein, human  0   *Molecular Chaperones *Protein Inhibitors of Activated STAT.
PIASx protein, rat  EC 6.-   *Ubiquitin-Protein Ligases *Protein Inhibitors of Activated STAT. Gene Expr Patterns 2003 Jun;3(3):301-8
PIASx protein, mouse  EC 6.-   *Ubiquitin-Protein Ligases *Protein Inhibitors of Activated STAT Ligases. Biochem Biophys Res Commun 2003 Aug 15;308(1);139-47
Piasy protein, mouse  0   *Protein Inhibitors of Activated STAT Nuclear Proteins Signal Transduction. J Mol Neurosci 2000 Feb-Apr;14(1-2):107-21
Su(var)2-10 protein, Drosophila  0   *Drosophila Proteins *Protein Inhibitors of Activated STAT Zinc Fingers. Gene 1999 Mar 18;229(1-2):109-18
Pias3 protein, rat  0   *Molecular Chaperones *Protein Inhibitors of Activated STAT. J Biol Chem 1998 May 8;273(19):11745-51
Pias3 protein, mouse  0   *Protein Inhibitors of Activated STAT Signal Transduction. Science 1997 Dec 5;278(5344):1803-5
PIAS1 protein, human  0   *Small Ubiquitin-Related Modifier Proteins *Protein Inhibitors of Activated STAT Nuclear Proteins RNA Nucleotidyltransferases. Biochem Biophys Res Commun 1997 Feb 12;234(2):335-40

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy