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Ankyrin Repeat

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Definition: Protein motif that contains a 33-amino acid long sequence that often occurs in tandem arrays. This repeating sequence of 33-amino acids was discovered in ANKYRIN where it is involved in interaction with the anion exchanger (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE). Ankyrin repeats cooperatively fold into domains that mediate molecular recognition via protein-protein interactions.      Other names ANK Repeat; Repeats, Ankyrin-Like; Repeats, Ankyrin; Repeats, ANK; Repeat, Ankyrin-Like; Repeat, Ankyrin; Repeat, ANK; Repeat Domains, Ankyrin; Repeat Domains, ANK; Repeat Domain, Ankyrin; Repeat Domain, ANK; Domains, Ankyrin Repeat; Domains, ANK Repeat; Domain, Ankyrin Repeat; Domain, ANK Repeat; Ankyrin-Like Repeat; Ankyrin Repeat Domain; Ankyrin Like Repeats; ANK Repeat Domain; Ankyrin-Like Repeats
 
SubstanceCAS Registry & nameCategoriesSource
anorexia protein, Drosophila  0   *Carrier Proteins *Drosophila Proteins Ankyrin Repeat. J Biol Chem. 2011 Nov 4;286(44):38417-26.
ProSAP2 protein, Xenopus  0   *Nerve Tissue Proteins *Xenopus Proteins Ankyrin Repeat. Dev Dyn 2011 Jun;240(6):1528-36
ProSAP1 protein, Xenopus  0   *Nerve Tissue Proteins *Xenopus Proteins Ankyrin Repeat. Dev Dyn 2011 Jun;240(6):1528-36
POTE ankyrin domain family, member H, human  0   *Proteins Antigens, Neoplasm Neoplasm Proteins Ankyrin Repeat. Brain Res 2011 May 19;1391:125-31
CHB-3 protein, C elegans  0   *Caenorhabditis elegans Proteins *Adaptor Proteins, Signal Transducing Ankyrin Repeat. PLoS Genet 2010;6(11):e1001211
ANK6 protein, Arabidopsis  0   *Repressor Proteins *Arabidopsis Proteins Ankyrin Repeat. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22332-7
ANKRD13C protein, human  0   *Membrane Proteins *Molecular Chaperones Ankyrin Repeat. J Biol Chem 2010 Dec 24;285(52):40838-51
panky protein, mouse  0   *Repressor Proteins Ankyrin Repeat. FEBS Lett 2010 Feb 19;584(4):753-8
ASPP protein, Drosophila  0   *Drosophila Proteins Ankyrin Repeat Tumor Suppressor Proteins. Dev Cell 2007 Dec;13(6):773-82
Varp protein, rat  0   *Guanine Nucleotide Exchange Factors Ankyrin Repeat.
Kidins220 protein, mouse  0   *Membrane Proteins Ankyrin Repeat. Dev Neurobiol 2009 Aug;69(9):547-57
DP58 protein, mouse  0   *Phosphoproteins Ankyrin Repeat. Cell Immunol 2009;258(2):172-80
liar protein, mouse  0   *Carrier Proteins Ankyrin Repeat. Blood 2009 Apr 16;113(16):3845-56
ASB9 protein, human  0   *Suppressor of Cytokine Signaling Proteins Ankyrin Repeat. Protein Pept Lett 2009;16(3):333-5
ClipR-59 protein, mouse  0   *Microtubule-Associated Proteins Ankyrin Repeat. Mol Cell Biol 2009 Mar;29(6):1459-71
Kank1 protein, mouse  0   *Carrier Proteins Ankyrin Repeat. J Cell Biol 2009 Jan 26;184(2):253-67
SamCystin protein, rat  0   *Nuclear Proteins Ankyrin Repeat. J Am Soc Nephrol 2005 Dec;16(12):3517-26
SamCystin protein, human  0   *Nuclear Proteins Ankyrin Repeat. Eur J Med Genet 2008 Jul-Aug;51(4):325-31
Varp protein, human  0   *Guanine Nucleotide Exchange Factors Ankyrin Repeat. Biochem Biophys Res Commun 2008 Jul 18;372(1):162-7
GSARP1 protein, mouse  0   *Carrier Proteins Ankyrin Repeat. Mol Biol Rep 2007 Dec;34(4):249-60
Ankrd11 protein, mouse  0   *DNA-Binding Proteins Ankyrin Repeat. Physiol Genomics 2008 Feb 19;32(3):311-21
Ankrd26 protein, mouse  0   *DNA-Binding Proteins *Transcription Factors Ankyrin Repeat. Proc Natl Acad Sci U S A 2008 Jan 8;105(1):270-5
gankyrin protein, mouse  0   *Transcription Factors Ankyrin Repeat. Int J Cancer 2008 Jan 15;122(2):325-32
mind bomb2 protein, Drosophila  0   *Carrier Proteins *Drosophila Proteins Zinc Fingers Ankyrin Repeat. J Cell Biol 2007 Oct 22;179(2):219-27
Fank1 protein, human  0   *DNA-Binding Proteins *Transcription Factors Ankyrin Repeat. Gene Expr Patterns 2007 Aug;7(7):777-83
ANR5 protein, Xenopus  0   *Xenopus Proteins Ankyrin Repeat. Curr Biol 2007 Jun 5;17(11):932-9
AKRP protein, Arabidopsis  0   *Carrier Proteins *Arabidopsis Proteins Ankyrin Repeat. Plant J 2006 Dec;48(6):895-906
santa protein, zebrafish  0   *Muscle Proteins *Zebrafish Proteins Ankyrin Repeat. Development 2006 Aug;133(16):3139-46
SHANK1 protein, mouse  0   *Membrane Proteins Ankyrin Repeat. J Neurosci 2006 Jul 19;26(29):7693-706
VPS9-ankyrin-repeat protein, mouse  0   *Guanine Nucleotide Exchange Factors Ankyrin Repeat. J Cell Sci 2006 Mar 15;119(Pt 6):1053-62
ASB15 protein, human  0   *Proteins Ankyrin Repeat. Int J Mol Med 2005 Aug;16(2):343-7
ANKHD1 protein, human  0   *RNA-Binding Proteins Ankyrin Repeat. FEBS J 2005 Aug;272(16):4091-102
Ankrd6 protein, rat  0   *Transcription Factors Ankyrin Repeat. Int J Mol Med 2005 Feb;15(2):359-63
ASB3 protein, human  0   *Suppressor of Cytokine Signaling Proteins Ankyrin Repeat. Mol Cell Biol 2005 Jun;25(11):4716-26
TANC protein, rat  0   *Lectins, C-Type Ankyrin Repeat. Eur J Neurosci 2005 Jan;21(2):339-50
XBAT32 protein, Arabidopsis  EC 6.3.2.19   *Arabidopsis Proteins *Ubiquitin-Protein Ligases Zinc Fingers Ankyrin Repeat. Plant J 2004 Dec;40(6):996-1006
nrarpb protein, zebrafish  0   *Zebrafish Proteins Signal Transduction Ankyrin Repeat.
nrarpa protein, zebrafish  0   *Zebrafish Proteins Signal Transduction Ankyrin Repeat.
Nrarp protein, mouse  0   *Proteins Signal Transduction Ankyrin Repeat.
HACE1 protein, human  EC 6.3.2.19   *Ubiquitin-Protein Ligases Ankyrin Repeat. Hum Mol Genet 2004 Sep 15;13(18):2061-74
BOP1 protein, Arabidopsis  0   *Arabidopsis Proteins Ankyrin Repeat. Plant Cell Physiol 2004 Oct;45(10):1361-70
diego protein, Drosophila  0   *Carrier Proteins *Drosophila Proteins Ankyrin Repeat. Development 2004 Sep;131(18):4467-76
ANKRD11 protein, human  0   *Repressor Proteins Ankyrin Repeat. J Biol Chem 2004 Aug 6;279(32):33799-805
Ccm1 protein, mouse  0   *Microtubule-Associated Proteins *Proto-Oncogene Proteins Ankyrin Repeat.
Ankrd1 protein, rat  0   *Muscle Proteins *Nuclear Proteins *Repressor Proteins Ankyrin Repeat.
ANKK1 protein, human  EC 2.7.1.37   *Protein-Serine-Threonine Kinases Signal Transduction Ankyrin Repeat. Hum Mutat 2004 Jun;23(6):540-5
Ankrd2 protein, mouse  0   *Muscle Proteins Ankyrin Repeat.
SHN-1 protein, C elegans  0   *Caenorhabditis elegans Proteins Ankyrin Repeat. FEBS Lett 2004 Mar 12;561(1-3):29-36
spergen-2 protein, rat  0   *Nuclear Proteins Spermatogenesis Ankyrin Repeat. Biol Reprod 2003 Aug;69(2):421-9
Uaca protein, mouse  0   *Membrane Proteins Muscle Proteins Leucine Zippers Ankyrin Repeat. J Biochem (Tokyo) 2003 Apr;133(4):429-36
KIDINS220 protein, human  0   *Membrane Proteins *Nerve Tissue Proteins Ankyrin Repeat. Eur J Immunol 2004 Jan;34(1):108-18
ANKRD17 protein, human  0   *DNA-Binding Proteins Ankyrin Repeat. J Biol Chem 2003 Dec 26;278(52):52290-7
VAB-19 protein, C elegans  0   *Cytoskeletal Proteins *Caenorhabditis elegans Proteins Ankyrin Repeat. Development 2003 Dec;130(23):5791-801
EF0377 protein, Enterococcus faecalis  0   *Bacterial Proteins Ankyrin Repeat. Acta Crystallogr D Biol Crystallogr 2003 Apr;59(Pt 4):755-7
USH1G protein, human  0   *Nerve Tissue Proteins Ankyrin Repeat. Hum Mol Genet 2003 Mar 1;12(5):463-71
Sans protein, mouse  0   *Nerve Tissue Proteins Ankyrin Repeat Usher Syndromes. Hum Mol Genet 2003 Mar 1;12(5):453-61
ANKTM1 protein, Drosophila  0   *Ion Channels *Drosophila Proteins Ankyrin Repeat. Nature 2003 Jun 19;423(6942):822-3
ANKRD23 protein, human  0   *Muscle Proteins *Nuclear Proteins Ankyrin Repeat. J Biol Chem 2003 Feb 7;278(6):3514-20
DARP protein, mouse  0   *Nuclear Proteins Ankyrin Repeat. J Biol Chem 2003 Feb 7;278(6):3514-20
ASB8 protein, human  0   *Suppressor of Cytokine Signaling Proteins Ankyrin Repeat. Biochem Biophys Res Commun 2003 Jan 24;300(4):972-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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