Definition: A negatively-charged extracellular matrix protein that plays a role in the regulation of BONE metabolism and a variety of other biological functions. Cell signaling by osteopontin may occur through a cell adhesion sequence that recognizes INTEGRIN ALPHA-V BETA-3.
Other names Sialoprotein I, Bone; Sialoprotein 1, Bone; Uropontin; Sialoprotein 1; Secreted Phosphoprotein 1; Bone Sialoprotein I; Bone Sialoprotein 1