Definition: An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor gene family. It was originally indentified in NERVE CELLS and may play a role in mediation of NERVE GROWTH FACTOR-induced CELL DIFFERENTIATION. However, several other functions have been attributed to this protein including the positive and negative regulation of APOPTOSIS.
Other names Orphan Nuclear Receptor NGFI B; Nerve Growth Factor inducible B Protein; NGFI B Orphan Nuclear Receptor; TR3 Orphan Nuclear Receptor; Orphan Nuclear Receptor TR3; Orphan Nuclear Receptor NR4A1; Orphan Nuclear Receptor NGFI-B; Orphan Nuclear Receptor HMR; Nur77 Orphan Nuclear Receptor; Nuclear Receptor NR4A1; Nerve Growth Factor-inducible B Protein; NGFI-B Orphan Nuclear Receptor; Early Response Protein NAK1