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Nuclear Receptor Subfamily 4, Group A, Member 1

More information in Books or onNLM PubMed
Definition: An orphan nuclear receptor that is closely related to members of the thyroid-steroid receptor gene family. It was originally indentified in NERVE CELLS and may play a role in mediation of NERVE GROWTH FACTOR-induced CELL DIFFERENTIATION. However, several other functions have been attributed to this protein including the positive and negative regulation of APOPTOSIS.      Other names Orphan Nuclear Receptor NGFI B; Nerve Growth Factor inducible B Protein; NGFI B Orphan Nuclear Receptor; TR3 Orphan Nuclear Receptor; Orphan Nuclear Receptor TR3; Orphan Nuclear Receptor NR4A1; Orphan Nuclear Receptor NGFI-B; Orphan Nuclear Receptor HMR; Nur77 Orphan Nuclear Receptor; Nuclear Receptor NR4A1; Nerve Growth Factor-inducible B Protein; NGFI-B Orphan Nuclear Receptor; Early Response Protein NAK1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane  0   *Indoles *Phenols Nuclear Receptor Subfamily 4, Group A, Member 1/antagonists & inhibitors. Cancer Res 2010 Sep 1;70(17):6824-36
NR4A1 protein, human  0   *Nuclear Receptor Subfamily 4, Group A, Member 1.
Nr4a1 protein, rat  0   *Nuclear Receptor Subfamily 4, Group A, Member 1 Immediate-Early Proteins.
Nr4a1 protein, mouse  0   *Nuclear Receptor Subfamily 4, Group A, Member 1.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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