Definition: A phosphatidylinositol 3-kinase subclass that includes enzymes with a specificity for 1-phosphatidylinositol, 1-phosphatidylinositol 4-phosphate, and 1-phosphatidylinositol 4,5-bisphosphate. Members of this enzyme subclass are activated by cell surface receptors and occur as heterodimers of enzymatic and regulatory subunits.
Other names Phosphatidylinositol 3 Kinase, Class I; Class I Phosphatidylinositol 3 Kinases; Class I Phosphatidylinositol 3 Kinase; Class I Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinase, Class I
