Definition: A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
lisofylline [ 1-(5'-hydroxyhexyl)-3,7-dimethylxanthine,1-(5R-hydroxyhexyl)-3,7-dimethylxanthine,3,7-dimethyl-1-(5-hydroxyhexyl)xanthine,A-802710,BL 194,CT-1501R ] metabolite of pentoxifylline; structure given in first source