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Adrenocorticotropic Hormone

More information in Books or onNLM PubMed
Definition: An anterior pituitary hormone that stimulates the ADRENAL CORTEX and its production of CORTICOSTEROIDS. ACTH is a 39-amino acid polypeptide of which the N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Upon further tissue-specific processing, ACTH can yield ALPHA-MSH and corticotrophin-like intermediate lobe peptide (CLIP).     
Pharmacological Action Hormones
See Also Petrosal Sinus Sampling; Receptors, Corticotropin 		Other names ACTH; Corticotropin; Adrenocorticotropin; Hormone, Adrenocorticotropic; Hormone, Adrenocorticotrophic; Corticotropin (1-39); Corticotrophin (1-39); Corticotrophin; Adrenocorticotrophic Hormone; ACTH (1-39); 1-39 ACTHDrugs* : ACTHAR; ACTH; PURIFIED CORTROPHIN GEL; H.P. ACTHAR GEL; CORTICOTROPIN; ACTHAR GEL-SYNTHETIC
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
corticotropin 4-10  0   *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Ann Univ Mariae Curie Sklodowska [Med] 2001;56():381-7
ACTH (4-12)  0   *Adrenocorticotropic Hormone *Peptide Fragments. J Exp Zool 2000 May 1;286(6):632-40
GMM2  0   *Neuropeptides Adrenocorticotropic Hormone. J Neurotrauma 1993 Winter;10(4):385-95
glutamyl-histidyl-phenylalanyl-arginyl-tryptophyl-glycyl-lysyl-prolyl-valyl-glycinamide cyclic peptide  94664-48-9   *Adrenocorticotropic Hormone *Peptide Fragments *Peptides, Cyclic. Zh Vyssh Nerv Deiat Im I P Pavlova 1993 Nov-Dec;43(6):1143-8
lysyl-histidyl-phenylalanyl-arginyl-tryptophyl-glycinamide  124051-38-3   *Adrenocorticotropic Hormone *Peptide Fragments. Zh Vyssh Nerv Deiat Im I P Pavlova 1993 Nov-Dec;43(6):1143-8
ACTH (13-24)  0   *Adrenocorticotropic Hormone *Peptide Fragments. Int J Pept Protein Res 1993 Jun;41(6):517-21
immunocorticotropin  150035-99-7 L-Valine, N-(N2-(N-(N-(N-(N-(1-(N2-(N2-L-valyl-L-lysyl)-L-lysyl)-L-prolyl)glycyl)-L-seryl)-L-seryl)-L-valyl)-L-lysyl)  *Immunoglobulin G *Peptide Fragments Adrenocorticotropic Hormone Immunoglobulin Variable Region Immunoglobulin Heavy Chains. Int J Pept Protein Res 1993 Jun;41(6):517-21
ACTH (1-17)-NH-(CH2)4-NH2, (Nalpha-(biotinyl-beta-Ala(1))-Lys(17))  0   *Adrenocorticotropic Hormone *Peptide Fragments Biotin/*analogs & derivatives. J Recept Res 1993;13(1-4):229-44
BIM 22015  141839-61-4 Glycinamide, D-alanyl-L-glutaminyl-L-tyrosyl-L-phenylalanyl-L-arginyl-L-tryptophyl-, acetate  *Adrenocorticotropic Hormone *Peptide Fragments. Brain Res 1992 Feb 7;571(2):218-29
Org 31433  132031-83-5 L-Phenylalanine, 4-(methylsulfinyl)-L-2-aminobutanoyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-D-lysyl-, 6-decyl ester  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Life Sci 1991;48(2):155
ACTH (7-16)NH2  57241-86-8 L-Lysinamide, L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl  *Peptide Fragments *Adrenocorticotropic Hormone. Life Sci 1989;45(8):703
ebiratide  105250-86-0   *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Peptides 1988;9(3):575
ACTH (6-9)  4289-02-5   *Adrenocorticotropic Hormone *alpha-MSH *Peptide Fragments. Arch Neurol 1987;44(10):995
ACTH, formylmethionyl  107949-95-1   Adrenocorticotropic Hormone/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1986;34(10):4362
ACTH (5-8)  103470-78-6   *Adrenocorticotropic Hormone *Peptide Fragments. Biull Eksp Biol Med 1986;101(5):519
actid  47931-80-6   *Adrenocorticotropic Hormone *Peptide Fragments. Gen Comp Endocrinol 1986;61(2):260
ACTH (4-7), Pro-Gly-Pro  80714-61-0   *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives Neprilysin/antagonists & inhibitors.
Pharma Action Enzyme Inhibitors ; Neuroprotective Agents ; Nootropic Agents 		Biull Eksp Biol Med 1986;101(3):267
ACTH (5-14)  24828-93-1   *Adrenocorticotropic Hormone *Peptide Fragments. Bioorg Khim 1984;10(10):1326
ACTH (1-37)  86836-91-1   *Adrenocorticotropic Hormone *Peptide Fragments. Regul Pept 1984;8(4):305
ACTH (7-39)  92307-51-2 alpha7-39-Corticotropin, 16-ethyl-3,20-dioxo-, (16alpha)  *Adrenocorticotropic Hormone *Peptide Fragments. Regul Pept 1984;8(4):305
ACTH (7-10)  51031-17-5   *Adrenocorticotropic Hormone *Peptide Fragments. Arch Biochem Biophys 1984;233(1):115
ACTH (25-39)  11138-17-3   *Adrenocorticotropic Hormone *Peptide Fragments. C R Seances Acad Sci [III] 1984;298(6):163
ACTH (1-16)  5576-42-1   *Adrenocorticotropic Hormone *Peptide Fragments. Neurosci Lett 1983;38(3):297
ACTH (1-14)  25696-21-3 alpha1-14-Corticotropin  *Adrenocorticotropic Hormone *Peptide Fragments. J Biol Chem 1983;258(12):7299
ACTH amide (1-16)  18806-03-6 alpha1-16-Corticotropin, 16-L-lysinamide  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Biochem Biophys Res Commun 1983;111(1):259
ACTH (27-39)  84605-07-2 alpha27-39-Corticotropin  *Adrenocorticotropic Hormone *Peptide Fragments. Brain Res 1982;251(1):177
ACTH, thiolglycine  83651-95-0 alpha1-39-Corticotropin, 31-L-serine-39a-(thioglycine)  Adrenocorticotropic Hormone/*analogs & derivatives. Int J Pept Protein Res 1982;20(2):97
ACTH (5-10)  4086-29-7   *Adrenocorticotropic Hormone *Peptide Fragments. Biull Eksp Biol Med 1982;93(5):3
ACTH amide (1-18), Gly(1)  0   *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives Delayed-Action Preparations. J Pharm Pharmacol 1982;34(5):342
ACTH (4-10), Phe(7)  39877-09-3 Glycine, N-(N-(N2-(N-(N-(N-L-methionyl-L-alpha-glutamyl)-L-histidyl)-D-phenylalanyl)-L-arginyl)-L-tryptophyl)  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Pharmacol Biochem Behav 1982;16(3):387
ACTH (1-32)  12393-19-0   *Adrenocorticotropic Hormone *Peptide Fragments. Acta Biochim Biophys Acad Sci Hung 1981;16(1-2):105
ACTH (4-11)  67224-41-3 L-Lysine, N2-(N-(N-(N2-(N-(N-(N-L-methionyl-L-alpha-glutamyl)-L-histidyl)-L-phenylalanyl)-L-arginyl)-L-tryptophyl)glycyl)  *Adrenocorticotropic Hormone *Peptide Fragments. Biochem Biophys Res Commun 1982;104(4):1484
ACTH (1-26), bis(Cys(25))  80208-73-7 alpha1-26-Corticotropin, 25-L-cysteine-, (25-25')-disulfide  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Biochem Biophys Res Commun 1981;102(2):697
ACTH (1-26), Cys-carboxamidomethyl(25)  80154-41-2 alpha1-26-Corticotropin, 25-(S-(2-amino-2-oxoethyl)-L-cysteine)  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Biochem Biophys Res Commun 1981;102(2):697
ACTH (1-38), Phe(2)-Nle(4)-iodo-Tyr(23)  79217-48-4 alpha1-38-Corticotropin, 2-L-phenylalanine-4-L-norleucine-23-(3-iodo-L-tyrosine)-31-L-serine  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Endocrinology 1981;109(1):10
ACTH (1-38), Phe(2)-Nle(4)  78783-29-6 alpha1-38-Corticotropin, 2-L-phenylalanine-4-L-norleucine-31-L-serine  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Endocrinology 1981;109(1):5
ACTH (4-7)  50842-42-7   *Adrenocorticotropic Hormone *Peptide Fragments. Dokl Akad Nauk SSSR 1980;255(6):1507
ACTH nonadecapeptide (1-19), Aib(1)-Lys(17,18,19)  59189-13-8 alpha1-19-Corticotropin, 1-(2-methylalanine)-17-L-lysine-18-L-lysine-19-L-lysinamide  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Acta Endocrinol 1981;96(4):464
ACTH (1-17)  7266-47-9   *Adrenocorticotropic Hormone *Peptide Fragments. Chronobiologia 1980;7(4):513
ACTH (4-9)  56236-83-0 L-Tryptophan, N-(N(2)-(N-(N-(N-L-methionyl-L-alpha-glutamyl)-L-histidyl)-L-phenylalanyl)-L-arginyl)  *Adrenocorticotropic Hormone *Peptide Fragments. Psychopharmacology 1980;71(1):67
ACTH (1-38)  0   *Adrenocorticotropic Hormone *Peptide Fragments. Biochem Biophys Res Commun 1980;96(3):1441
ACTH (17-39)  11138-16-2 alpha17-39-Corticotropin  *Adrenocorticotropic Hormone *Peptide Fragments. Gen Comp Endocrinol 1980;42(1):110
beta-cell tropin  75788-99-7 beta-Cell tropin  *Adrenocorticotropic Hormone *Peptide Fragments. FEBS Lett 1980;117(1):303
ACTH, 2-nitro-5-azidophenylsulfenyl  73905-69-8 alpha1-39-Corticotropin, 9-(2-((5-azido-2-nitrophenyl)thio)-L-tryptophan)  Adrenocorticotropic Hormone/*analogs & derivatives. Biochemistry 1980;19(14):3280
ACTH, 2-nitro-4-azidophenylsulfenyl  73905-68-7 alpha1-39-Corticotropin, 9-(2-((4-azido-2-nitrophenyl)thio)-L-tryptophan)  Adrenocorticotropic Hormone/*analogs & derivatives. Biochemistry 1980;19(14):3280
ACTH, 2,4-dinitro-5-azidophenylsulfenyl  73905-66-5 alpha1-39-Corticotropin, 9-(2-((5-azido-2,4-dinitrophenyl)thio)-L-tryptophan)  Adrenocorticotropic Hormone/*analogs & derivatives. Biochemistry 1980;19(14):3275
ACTH (1-4)  19405-50-6 L-methionine, N-(N-(N-L-seryl-L-tyrosyl)-L-seryl)  *Adrenocorticotropic Hormone *Peptide Fragments. Arch Biochem Biophys 1980;203(1):288
ACTH (7-38)  68563-24-6   *Adrenocorticotropic Hormone *Peptide Fragments.
Pharma Action Hormone Antagonists 		Arch Biochem Biophys 1980;201(2):411
ACTH amide (1-10), Phe(7)  74873-14-6 Glycinamide, L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Adv Biochem Psychopharmacol 1980;22:305
ACTH, 2-nitrophenylsulfenyl  0   Adrenocorticotropic Hormone/*analogs & derivatives. Mol Cell Endocrinol 1980;17(3):171
ACTH, biotinyl  61125-54-0 alpha1-25-Corticotropin, 25-(N(6)-(5-(hexahydro-2-oxo-1H-thieno(3,4-d)imidazol-4-yl)-1-oxopentyl)-L-lysinamide)-, (3aS-(3aalpha,4beta,6aalpha))  Adrenocorticotropic Hormone/*analogs & derivatives. Biochem Biophys Res Commun 88(3):1153;1979
ACTH nonadecapeptidamide (1-19), (Trp(2,5,7-Bu(t)3)9)  0   *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Hoppe Seylers Z Physiol Chem 360(1):9;1979; Hoppe Seylers Z Physiol Chem 360(1):1;1979
ACTH nonadecapeptidamide (1-19), (t-butyl-Trp)(9)  0   *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Hoppe Seylers Z Physiol Chem 360(1):1;1979; Hoppe Seylers Z Physiol Chem 360(1):9;1979
ACTH amide alpha (1-18), Gly(1)  24870-04-0 alpha1-18-Corticotropin, 1-glycine-18-L-argininamide  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives. Chem Pharm Bull 26(4):1061;1978
ACTH alpha (1-18)  1285-85-4 alpha1-18-Corticotropin  *Adrenocorticotropic Hormone *Peptide Fragments. Clin Endocrinol 7(1):1;1977
ACTH, nitrophenylsulphenyl  0   Adrenocorticotropic Hormone/*analogs & derivatives. Ann NY Acad Sci 307:378;1978; Biochem J 160(1):1;1976
Org 2766  50913-82-1 L-phenylalanine, gamma-(methylsulfonyl)-L-alpha-aminobutyryl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-D-lysyl  *Peptide Fragments Adrenocorticotropic Hormone/*analogs & derivatives.
Pharma Action Anticonvulsants 		Neuropeptides 5(Suppl 1):53;1976
acethropan-S  20566-04-5 corticotropin-(1-23)-tricosipeptide amide  *Adrenocorticotropic Hormone *Peptide Fragments. Arzneim Forsch 26(5):919;1976
ACTH (4-10)  4037-01-8 N-(N-(N(2)-(N-(N-(N-L-methionyl-L-alpha-glutamyl)-L-histidyl)-L-phenylalanyl)-L-arginyl)-L-tryptophyl)glycine  *Adrenocorticotropic Hormone *Peptide Fragments Melanocyte-Stimulating Hormones.
Pharma Action Nootropic Agents 		Ann Neurol 1(3):270;1977; Dokl Akad Nauk SSSR 240(5):1245;1978; Eur J Pharmacol 1979:57(4):353; Frontiers Hormone Res 4:129;1976; J Neurochem 32(4):977;1978; Prog Brain Res 42:163;1975; Prog Brain Res 42:187;1975; Prog Brain Res 42:209;1975; Prog Brain Res 42:275;1975; Psychopharmacology (Berlin) 61(2):161;1979
ACTH (1-10)  4037-00-7   *Adrenocorticotropic Hormone *Peptide Fragments. Dokl Akad Nauk SSSR 240(5):1245;1978; Prog Brain Res 42:187;1975
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