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Carboxypeptidases

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Definition: Enzymes that act at a free C-terminus of a polypeptide to liberate a single amino acid residue.  general or unspecified; prefer specifics   
Examples Carboxypeptidase B; Carboxypeptidase H; Carboxypeptidase U; Carboxypeptidases A; Cathepsin A; Cathepsin Z; gamma-Glutamyl Hydrolase; Glutamate Carboxypeptidase II; Lysine Carboxypeptidase; Muramoylpentapeptide Carboxypeptidase; Serine-Type D-Ala-D-Ala Carboxypeptidase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
AGBL2 protein, human  EC 3.4.17.-   *Carboxypeptidases. Cancer Res 2011 Feb 15;71(4):1219-28
SURO-1 protein, C elegans  EC 3.4.-   *Carboxypeptidases *Caenorhabditis elegans Proteins. FEBS Lett 2011 Jan 3;585(1):121-7
glutamate carboxypeptidase III, human  EC 3.4.17.11   *Carboxypeptidases. J Neurochem 2007 May;101(3):682-96
CPC protein, S cerevisiae  EC 3.4.16.1   *Carboxypeptidases *Saccharomyces cerevisiae Proteins. FEBS Lett 2007 Apr 17;581(8):1681-7
CPY protein, S cerevisiae  EC 3.4.16.1   *Carboxypeptidases *Saccharomyces cerevisiae Proteins. FEBS Lett 2007 Apr 17;581(8):1681-7
CPVL protein, human  EC 3.4.16.-   *Carboxypeptidases. Int J Exp Pathol 2006 Feb;87(1):29-39
Sp7 protein, Drosophila  EC 3.4.16.1   *Carboxypeptidases *Drosophila Proteins. Biochem Biophys Res Commun 2005 Dec 16;338(2):1075-82
AMP1 protein, Arabidopsis  EC 3.4.17.11   *Carboxypeptidases *Arabidopsis Proteins. Plant Cell 2005 Sep;17(9):2473-85
grifolisin, Grifola frondosa  EC 3.4.16.1   *Carboxypeptidases. Phytochemistry 2005 May;66(9):983-90
carboxypeptidase Z  EC 3.4.16.1   *Carboxypeptidases.
Cpz protein, rat  EC 3.4.-   *Carboxypeptidases.
Cpz protein, mouse  EC 3.4.-   *Carboxypeptidases.
CPZ protein, human  EC 3.4.-   *Carboxypeptidases.
BRS1 protein, Arabidopsis  EC 3.4.16.1   *Carboxypeptidases *Arabidopsis Proteins.
Scpep1 protein, mouse  EC 3.4.16.-   *Carboxypeptidases.
Risc protein, rat  EC 3.4.16.-   *Carboxypeptidases.
AEBP1 protein, human  0   *Carboxypeptidases *Repressor Proteins Carboxypeptidases.
sedolisin  EC 3.4.16.1   *Carboxypeptidases. Acta Biochim Pol. 2003;50(1):81-102
SCPEP1 protein, human  EC 3.4.16.-   *Carboxypeptidases. J Biol Chem 2001 Sep 7;276(36):34175-81
carboxypeptidase-aminoacylase PP  EC 3.-   *Amidohydrolases *Carboxypeptidases *Multienzyme Complexes. Appl Environ Microbiol 2001 Feb;67(2):673-9
UCHL5 protein, human  EC 3.4.19.12   *Carboxypeptidases. FEBS Lett 2001 Jan 19;488(3):201-5
PfuCP carboxypeptidase, Pyrococcus furiosus  EC 3.4.17.-   *Carboxypeptidases *Archaeal Proteins. Protein Sci 1999 Nov;8(11):2474-86
PdcA protein, Myxococcus xanthus  EC 3.4.-   *Bacterial Proteins *Carboxypeptidases Drug Resistance, Microbial. J Bacteriol 1999 Aug;181(15):4696-9
MCBP protein, Metarhizium anisopliae  EC 3.4.17.-   *Carboxypeptidases *Fungal Proteins. J Biol Chem 1999 Apr 2;274(14):9803-11
metallocarboxypeptidase Z  EC 3.4.17.-   *Carboxypeptidases. J Biol Chem 1997 Apr 18;272(16):10543-50
VanY protein, Bacteria  EC 3.4.16.4   *Bacterial Proteins *Carboxypeptidases *Membrane Proteins Drug Resistance, Microbial. Mol Microbiol 1998 Nov;30(4):819-30
Aebp1 protein, mouse  0   *Carboxypeptidases *Repressor Proteins. J Biol Chem 1998 Jun 19;273(25):15654-60
Sxa2 protein, S pombe  EC 3.4.16.-   *Carboxypeptidases *Schizosaccharomyces pombe Proteins. Biochem Soc Trans 1995 Nov;23(4):565S
ferritin associated protein, human  EC 3.4.17.1   *Carboxypeptidases *Carrier Proteins. Biochem Biophys Res Commun 1996 Nov 21;228(3):683-9
GM7 protein, Solanum brevidens  0   *Plant Proteins Carboxypeptidases/antagonists & inhibitors. FEBS Lett 1996 Apr 1;383(3):159-64
belactin B  0   *Glucosides *Lactones Carboxypeptidases/antagonists & inhibitors. J Enzym Inhib 1995;9(4):263-75
belactin A  0   *Benzamides *Lactones Carboxypeptidases/antagonists & inhibitors. J Enzym Inhib 1995;9(4):263-75
Lxn protein, rat  0   *Glycoproteins Carboxypeptidases/antagonists & inhibitors. Proc Natl Acad Sci U S A 1995 Dec 19;92(26):12225-9
CpsA protein, Sulfolobus solfataricus  EC 3.4.17.-   *Bacterial Proteins *Carboxypeptidases. J Bacteriol 1995 Oct;177(19):5561-6
G deamidase  EC 3.4.16.-   *Carboxypeptidases. Biochem Pharmacol 1995 Aug 25;50(5):585-90
metallocarboxypeptidase D  EC 3.4.17.22   *Proteins Carboxypeptidases Membrane Glycoproteins Drosophila Proteins. J Biol Chem 1995 Jun 23;270(25)15022-8
procarboxypeptidase E  EC 3.4.17.-   *Carboxypeptidases *Enzyme Precursors. J Neurochem 1995 Jul;65(1):444-53
carboxypeptidase PC  EC 3.4.-   *Carboxypeptidases. Bioorg Khim 1995 Apr;21(4):249-55
47-kDa immunogen, Treponema pallidum  0   *Carrier Proteins *Lipoproteins Antigens, Bacterial Carboxypeptidases Treponema pallidum. Proc Natl Acad Sci U S A 1994 Nov 22;91(24):11611-5
Thermus aquaticus carboxypeptidase  EC 3.4.17.19   *Bacterial Proteins *Carboxypeptidases. Biosci Biotechnol Biochem 1994 Aug;58(8):1490-5
mitochondrial carboxypeptidase-III  EC 3.4.17.-   *Carboxypeptidases. Biochem J 1994 May 15;300( Pt 1):15-9
carboxypeptidase G3  EC 3.4.17.-   *Carboxypeptidases. Biosci Biotechnol Biochem 1992 Oct;56(10):1536-40
carboxypeptidase D  EC 3.4.16.6   *Carboxypeptidases Saccharomyces cerevisiae Proteins. J Cell Biol 1992 Dec;119(6):1459-68
CPT protein, Thermoactinomyces vulgaris  EC 3.4.17.18   *Bacterial Proteins *Carboxypeptidases. Eur J Biochem 1992 Sep 1;208(2):281-8
photosystem II, D1 polypeptide carboxy-terminal processing protease  EC 3.4.99.-   *Carboxypeptidases *Proprotein Convertases. J Biol Chem 1992 Mar 15;267(8):5424-33
VCP protein, Aedes aegypti  EC 3.4.16.-   *Carboxypeptidases *Insect Proteins. Proc Natl Acad Sci USA 1991;88(23):10821
SCPD protein, Streptomyces griseus  EC 3.4.17.-   *Bacterial Proteins *Carboxypeptidases. J Biochem (Tokyo) 1990;107(6):879
CP-MIII protein, Hordeum vulgare  EC 3.4.16.5   *Carboxypeptidases *Plant Proteins. Carlsberg Res Commun 1989;54(5):193
CP-MII protein, Hordeum vulgare  EC 3.4.16.6   *Carboxypeptidases *Plant Proteins. Anal Biochem 1989;180(1):28
preprocarboxypeptidase H  EC 3.4.17.-   *Carboxypeptidases *Enzyme Precursors. J Biol Chem 1989;264(10):5988
N-formylmethionyl-leucyl-phenylalanine carboxypeptidase  EC 3.4.-   *Carboxypeptidases. J Periodont Res 1988;23(4):245
CP-MI protein, Hordeum vulgare  EC 3.4.16.-   *Carboxypeptidases *Plant Proteins. J Biol Chem 1988;263(23):11106
angiotensin-related carboxypeptidase  EC 3.4.-   *Carboxypeptidases. Regul Pept 1988;20(4):273
carboxypeptidase L  EC 3.4.16.5   *Carboxypeptidases. Biokhimiia 1987;52(12):2002
5-benzamido-2-benzyl-4-oxopentanoic acid  109138-11-6   *Keto Acids Carboxypeptidases/antagonists & inhibitors. Proc Natl Acad Sci USA 1987;84(6):1512
urinary carboxypeptidase  EC 3.4.17.-   *Carboxypeptidases. Adv Exp Med Biol 1986;198(Pt A):381
carboxypeptidase K  EC 3.4.17.-   *Carboxypeptidases. Biochem J 1984;221(2):465
non-stereospecific dipeptidase  EC 3.4.13.17   *Carboxypeptidases. J Biol Chem 1984;259(7):4237
calmodulin converting enzyme  EC 3.4.-   *Carboxypeptidases. Methods Enzymol 1983;102:158
N-alpha-acetylenkephalin carboxypeptidase  EC 3.4.17.-   *Carboxypeptidases Alkynes. Biochem J 1983;209(2):471
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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