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Carubicin

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Definition: A very toxic anthracycline-type antineoplastic related to DAUNORUBICIN, obtained from Actinomadura carminata.     
Pharmacological Action Antibiotics, Antineoplastic 		Other names Karminomycin; Carminomycin; NSC180024; NSC180,024; NSC 180024; NSC 180,024; Hydrochloride, Carubicin; Rubeomycin A1; Rubeomycin A; NSC-180024; NSC-180,024; Karminomicin; Demethyldaunorubicin; Demethyldaunomycin; Carubicin Hydrochloride; Carminomycin III; Carminomycin II; Carminomycin I; Carminomicin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
14-hydroxycarminomycin  0   Carubicin/*analogs & derivatives. J Antibiot (Tokyo) 2004 Feb;57(2):143-50
1-hydroxy-13-deoxocarminomycin  145066-22-4   Carubicin/*analogs & derivatives. J Antibiot (Tokyo) 1992 Oct;45(10):1609-17
14-salicyloylcarubicin  116907-26-7   Carubicin/*analogs & derivatives. Antibiot Khimioter 1990;35(2):24
14-chlorocarubicin  126722-64-3   Carubicin/*analogs & derivatives. Antibiot Khimioter 1990;35(2):24
13-deoxy-10-hydroxycarminomycin  0   Carubicin/*analogs & derivatives. J Antibiot (Tokyo) 1989;42(9):1424
SN 706  114511-93-2 Antibiotic SN 706  Carubicin/*analogs & derivatives. J Antibiot (Tokyo) 1988;41(12):1918
13-dihydrocarminomycinone  62152-30-1   Carubicin/*analogs & derivatives. Antibiot Khimioter 1988;33(8):574
morpholinoanthracycline MX2  105026-50-4   Carubicin/*analogs & derivatives.
Pharma Action Antibiotics, Antineoplastic 		J Antibiot (Tokyo) 1987;40(7):1058
14-N-succinimidocarminomycin  108936-90-9   Carubicin/*analogs & derivatives. Antibiot Med Biotekhnol 1987;32(4):254
14-carminomycyl-N-pyridinium  108936-91-0   Carubicin/*analogs & derivatives. Antibiot Med Biotekhnol 1987;32(4):254
CCP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carubicin Cisplatin Cyclophosphamide. Semin Surg Oncol 1986;2(1):1
10-carboxy-13-deoxocarminomycin  97583-07-8   Carubicin/*analogs & derivatives. J Antibiot (Tokyo) 1986;39(3):473
13-deoxycarminomycin  76034-18-9   Carubicin/*analogs & derivatives. J Nat Prod 1985;48(3):435
1-hydroxy-11-deoxycarminomycin II  98791-58-3   Carubicin/*analogs & derivatives. J Antibiot (Tokyo) 1985;38(6):821
carminomycin-iron complex  0   *Carubicin *Organometallic Compounds Iron. Biochim Biophys Acta 1985;840(1):91
carminomycin 13-cyclohexylidenehydrazone  85145-53-5   Carubicin/*analogs & derivatives. Antibiotiki 1984;29(5):374
N-formyl-13-dihydrocarminomycin  76634-96-3 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(1-hydroxyethyl)-10-((2,3,6-trideoxy-3-(formylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (8S-cis)  Carubicin/*analogs & derivatives. J Antibiot (Tokyo) 1983;36(4):457
CD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Carubicin Mitolactol. Neoplasma 1982;29(6):741
carminazine  79862-95-6 5,12-Naphthacenedione, 8,8'-(azinodiethylidyne)bis(10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, dihydrochloride, (8S-(8alpha,8(8R*,10S*),10alpha)))  Carubicin/*analogs & derivatives. Antibiotiki 1981;26(8):617
carminomycin 11-methyl ether  70561-45-4 5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-1,8,11-trihydroxy-6-methoxy-, (8S-cis)  Carubicin/*analogs & derivatives. Cancer Res 40(2):387;1980
trisarubicinol  80470-08-2 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(1-hydroxyethyl)-10-((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy  Carubicin/*analogs & derivatives. J Antibiot (Tokyo) 1981;34(11):1492
carminazone  69428-33-7 Benzoic acid, (1-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,7,12-tetrahydroxy-6,11-dioxo-2-naphthacenyl)ethylidene)hydrazide, monohydrochloride, (2S-cis)  Carubicin/*analogs & derivatives. Antibiotiki 23(4):356;1978
dihydrocarminomycin  62182-86-9 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(1-hydroxyethyl)  Carubicin/*analogs & derivatives. Antibiotiki 23(1):78;1978
carminomycinone  52744-22-6   Carubicin/*analogs & derivatives. Antibiotiki 22(12):1085;1977
14-oxycarminomycin  64248-76-6 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(hydroxyacetyl)-, hydrochloride, (8S-cis)  Carubicin/*analogs & derivatives. Antibiotiki 22(8):693;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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