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Complement Activating Enzymes

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Definition: Enzymes that activate one or more COMPLEMENT PROTEINS in the complement system leading to the formation of the COMPLEMENT MEMBRANE ATTACK COMPLEX, an important response in host defense. They are enzymes in the various COMPLEMENT ACTIVATION pathways.     
Pharmacological Action Immunologic Factors
Examples Complement C1r; Complement C1s; Complement Factor D 		Other names Enzymes, Complement Activating; Activating Enzymes, Complement
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RHP protein, human  0   *Blood Proteins Antibodies Arthritis, Rheumatoid Complement Activating Enzymes Biological Markers. Biochem Biophys Res Commun 1985;128(3):1288
complement 1q receptor  0   *Membrane Glycoproteins *Receptors, Complement Complement Activating Enzymes Phagocytosis Complement C1q Molecular Chaperones. J Biol Chem 1981;256(21):10924

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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